2. Gene
  3. TUBE1 - tubulin epsilon 1 Gene

TUBE1 - tubulin epsilon 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as TUBE; dJ142L7.2

Gene ID: 51175 | Gene type: protein coding

About TUBE1

Cytogenetic location: 6q21 Genomic coordinates (GRCh38): 6:112,070,663-112,087,482 (from NCBI)

This gene has 11 transcripts (splice variants), 209 orthologues and 23 paralogues. Broad expression in testis (RPKM 21.9), endometrium (RPKM 10.2) and 25 other tissues.

Summary

This gene encodes a member of the tubulin superfamily. This protein localizes to the centriolar sub-distal appendages that are associated with the older of the two centrioles after centrosome duplication. This protein plays a central role in organization of the microtubules during centriole duplication. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Jan 2009]

TUBE1 Products(1)

mRNA Protein Name
NM_016262.5 NP_057346.1 tubulin epsilon chain

TUBE1 Protein Structure

Tubulin

Tubulin: Tubulin/FtsZ family, GTPase domain (5 - 220)

Tubulin_C

Tubulin_C: Tubulin C-terminal domain (294 - 413)

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  • 475 a.a.
Protein Preferred Names Protein Names

tubulin epsilon chain

epsilon-tubulin

Related Diseases

Diseases Alias
Bladder Exstrophy

Exstrophy Of The Bladder

Classic Exstrophy Of The Bladder
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-147186 5,5'-Difluoro BAPTA / Unkown
HY-D1640 5',5-Difluoro BAPTA tetrapotassium / Unkown
HY-RS15260 TUBE1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus TUBE1 VGNC VGNC:36511
Mus musculus TUBE1 MGD MGI:1919174
Canis familiaris TUBE1 VGNC VGNC:54383
Rattus norvegicus TUBE1 RGD RGD:1306048
Macaca mulatta TUBE1 VGNC VGNC:79284
Felis catus TUBE1 VGNC VGNC:66703