2. Gene
  3. RXFP3 - relaxin family peptide receptor 3 Gene

RXFP3 - relaxin family peptide receptor 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as SALPR; RLN3R1; RXFPR3; GPCR135

Gene ID: 51289 | Gene type: protein coding

About RXFP3

Cytogenetic location: 5p13.2 Genomic coordinates (GRCh38): 5:33,936,386-33,938,918 (from NCBI)

This gene has 1 transcript (splice variant), 1 gene allele, 101 orthologues and 7 paralogues.

Summary

Predicted to enable G protein-coupled peptide receptor activity. Involved in positive regulation of cytokinesis. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

RXFP3 Products(1)

mRNA Protein Name
NM_016568.3 NP_057652.1 relaxin-3 receptor 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of cytokinesis IMP
IMP: Inferred from mutant phenotype
22888021 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RXFP3 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (98 - 196)

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (214 - 389)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 469 a.a.
Protein Preferred Names Protein Names

relaxin-3 receptor 1

G-protein coupled receptor GPCR135

Related Diseases

Diseases Alias
Schizotypal Personality Disorder

Schizotypal Personality
Chromosome 5p13 Duplication Syndrome

5p13 Microduplication Syndrome

Trisomy 5p13

Dup(5)(P13)
Chondroid Chordoma
Radiation Cystitis

Irradiation Cystitis
Chordoid Meningioma

Meningioma, Chordoid
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-150700 RLX-33 Modulator 99.79% Unkown
HY-145278 RXFP3/4 agonist 2 99.82% Unkown
HY-111583 RXFP3/4 agonist 1 / Unkown
HY-145279 RXFP3 agonist 1 / Unkown
HY-RS12359 RXFP3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus RXFP3 MGD MGI:2441827
Felis catus RXFP3 VGNC VGNC:64833
Rattus norvegicus RXFP3 RGD RGD:1311550
Bos taurus RXFP3 VGNC VGNC:58407
Macaca mulatta RXFP3 VGNC VGNC:110436