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GZMA

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Cat. No. Compare Product Name Species Source
  • HY-P72220
    GZMA/Granzyme A Protein, Mouse (His-B2M)

    GZMA; Ctla-3; Ctla3; Mtsp-1; Granzyme A; EC 3.4.21.78; Autocrine thymic lymphoma granzyme-like serine protease; CTLA-3; Fragmentin-1; T cell-specific serine protease 1; TSP-1

    		 Mouse E. coli
    GZMA/Granzyme A, abundant in cytotoxic T-cells and natural killer cells, crucially induces caspase-independent pyroptosis upon delivery into target cells. With substrate specificity for lysine or arginine residues, GZMA cleaves APEX1 and nucleosome assembly protein SET, disrupting their activities. This multifunctional protein plays a significant role in diverse cellular processes during immune responses. GZMA/Granzyme A Protein, Mouse (His-B2M) is the recombinant mouse-derived GZMA/Granzyme A protein, expressed by E. coli, with N-6*His, N-B2M labeled tag. The total length of GZMA/Granzyme A Protein, Mouse (His-B2M) is 232 a.a., with molecular weight of ~39.6 kDa.

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