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Pathways Recommended: Antibody-drug Conjugate/ADC Related
Results for "

chemotherapeutic drug

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Screening Libraries

1

Fluorescent Dye

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D1504

    Fluorescent Dye Others
    IR-797 chloride is a near-infrared (NIR) dye. IR 797 has absorption maxima near 700 nm. IR-797 shows some aggregation-induced-emission (AIE) properties. IR-797 shows shows cytotoxic .
    IR-797 chloride
  • HY-147271

    Drug-Linker Conjugates for ADC Topoisomerase Cancer
    Mal-PEG8-Val-Ala-PAB-Exatecan (Compound 9b) is an antibody-drug conjugate linker (ADC linker) that binds to Nectin-4 polypeptides conjugated to chemotherapeutic agents. Mal-PEG8-Val-Ala-PAB-Exatecan can be used for cancer research .
    Mal-PEG8-Val-Ala-PAB-Exatecan
  • HY-150644
    S07-2010
    1 Publications Verification

    Others Cancer
    S07-2010 is a potent pan-AKR1C (aldo-keto reductase family 1 member C) inhibitor, with IC50 values of 0.19, 0.36, 0.47, and 0.73 μM for AKR1C3, AKR1C4, AKR1C1 and AKR1C2, respectively. S07-2010 induces apoptosis in A549/DDP cells. S07-2010 strengthens the cytotoxicity of chemotherapeutic agents in drug-resistant cells. S07-2010 significantly inhibits the proliferation of drug-resistant cells .
    S07-2010
  • HY-B0245
    Busulfan
    Maximum Cited Publications
    14 Publications Verification

    DNA Alkylator/Crosslinker Apoptosis Inflammation/Immunology Cancer
    Busulfan is a potent alkylating antineoplastic agent. Busulfan causes DNA damage by cross-linking DNAs and DNA and proteins. Busulfan inhibits thioredoxin reductase. Busulfan induces apoptosis. Busulfan is an immunosuppressive and myeloablative chemotherapeutic agent .
    Busulfan
  • HY-B0245S

    DNA Alkylator/Crosslinker Apoptosis Inflammation/Immunology Cancer
    Busulfan-d8 is a deuterium labeled Busulfan. Busulfan is a potent alkylating antineoplastic agent. Busulfan causes DNA damage by cross-linking DNAs and DNA and proteins. Busulfan inhibits thioredoxin reductase. Busulfan induces apoptosis. Busulfan is an immunosuppressive and myeloablative chemotherapeutic agent[1][2][3].
    Busulfan-d8
  • HY-19542
    C6 Ceramide
    2 Publications Verification

    C6-Cer; N-Hexanoylsphingosine

    Apoptosis Cancer
    C6 Ceramide (C6-Cer) is a short-chain, cell-permeable ceramide pathway activator with anticancer activity. C6 Ceramide-mediated miR-29b expression participates in the progression of multiple myeloma through suppressing the proliferation, migration and angiogenesis of endothelial cells by targeting Akt signal pathway. C6 Ceramide exhibits multiple anti-cancer properties including cell cycle arrest, Apoptosis, inhibition of tumor growth and enhances the effects of chemotherapy in drug-resistant cancer cells. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects .
    C6 Ceramide
  • HY-123526

    NSC305458

    BCRP Cancer
    NSC 265473 is an ABCG2 substrate .
    NSC265473
  • HY-19542S1

    C6-Cer-d11; N-Hexanoylsphingosine-d11

    Apoptosis Isotope-Labeled Compounds Cancer
    C6 Ceramide-d11 is deuterated labeled C6 Ceramide (HY-19542). C6-ceramide, a ceramide pathway activator, shows activity against a variety of cancer cell lines. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects .
    C6 Ceramide-d11
  • HY-123870

    Survivin IAP NF-κB Inflammation/Immunology Cancer
    MX107 is a selective and potent survivin inhibitor that suppresses triple-negative breast cancer (TNBC) cell proliferation. MX107 induces degradation of survivin and inhibitor-of-apoptosis proteins (IAPs), which inhibits nuclear factor κB (NF-κB) activation induced by DNA damage. MX107 enhances tumoricidal efficacy of genotoxic treatments synergized with chemotherapeutic drugs .
    MX107

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