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Results for "

nsp16

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Peptides

2

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108986
    JFD00244

    		Sirtuin SARS-CoV Cancer
    JFD00244 is a sirtuin 2 (SIRT2) inhibitor, with anti-tumor effect. JFD00244 is also a Nsp-16 inhibitor against SARS-CoV-2 .
    JFD00244
  • HY-W024485
    SARS-CoV-2-IN-86

    		SARS-CoV Infection
    SARS-CoV-2-IN-86 (Compound 2734589) is a dual inhibitor of the methyltransferases nsp14 and nsp16 of SARS-CoV-2. SARS-CoV-2-IN-86 exhibits low toxicity with a LD50 of 700 mg/kg according to toxicity analysis predict .
    SARS-CoV-2-IN-86
  • HY-124654
    SS148

    		SARS-CoV Metabolic Disease
    SS148 is a dual inhibitor of nsp14/nsp16 MTase. SS148 significant inhibits nsp10–nsp16 with an IC50 of 1.2 μM .
    SS148
  • HY-163614
    SARS-CoV-2-IN-87

    		SARS-CoV DNA Methyltransferase Infection
    SARS-CoV-2-IN-87 (compound 138968421) is a potent inhibitor of methyltransferases (nsp14 and nsp16) of SARS-CoV-2 .
    SARS-CoV-2-IN-87
  • HY-155280
    SARS-CoV-2-IN-60

    		SARS-CoV Infection
    SARS-CoV-2-IN-60 (compound 5a) is an S-adenosylmethionine (SAM)-competitive and irreversible SARS-CoV-2 nsp16-nsp10 methyltransferase activity inhibitor with an IC50 of 9 μM and a Ki of 26 μM. SARS-CoV-2-IN-60 can specifically occupy a newly identified pocket adjacent to the SAM-binding site on nsp16. SARS-CoV-2-IN-60 has the potential for pan-coronavirus therapeutics .
    SARS-CoV-2-IN-60

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