Search Result
Results for "
para
" in MedChemExpress (MCE) Product Catalog:
5
Biochemical Assay Reagents
8
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-165831
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- HY-165836
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- HY-120870
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Myosin
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Metabolic Disease
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para-Nitroblebbistatin is a non-cytotoxic, photostable, fluorescent and specific Myosin II inhibitor, usd in the study of the specific role of myosin II in physiological, developmental, and cell biological studies .
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- HY-111474
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Myosin
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Cardiovascular Disease
Neurological Disease
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Para-aminoblebbistatin is a highly water soluble, non-fluorescent and photostable C15 amino-substituted derivative of blebbistatin; inhibits various (myosin II) isoforms both in vitro and in vivo.
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- HY-15928
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para-nitrophenyl phosphate disodium
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Fluorescent Dye
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Others
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PNPP (Para-nitrophenyl phosphate) disodium is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays.
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- HY-15632
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Fluorescent Dye
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Others
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para-iodoHoechst 33258 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution .
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- HY-W739835
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- HY-W750432
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- HY-G0005
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para-Naphthol duloxetine
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Drug Metabolite
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Neurological Disease
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Para-Naphthol Duloxetine is a metabolite of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor (SNRI).
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- HY-118380
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4-Nitrobenzyl mesylate; para-Nitrobenzyl mesylate; PNBM
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Others
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Metabolic Disease
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p-Nitrobenzyl mesylate (4-Nitrobenzyl mesylate; para-Nitrobenzyl mesylate) is a reagent used to alkylate phosphorothioates, forming phosphorothioate epitopes that can be recognized by specific antibodies.
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- HY-D1045
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DABCYL; para-methyl red
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Fluorescent Dye
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Others
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Dabcyl acid (Dabcyl) is the original dark fluorescence quencher.
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- HY-D1045A
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DABCYL sodium; para-methyl red sodium
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Fluorescent Dye
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Others
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Dabcyl acid sodium (DABCYL sodium) is a nonfluorescent chromophore and a quencher. Dabcyl acid sodium can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions .
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- HY-18775
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para-topolin riboside
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P2Y Receptor
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Cardiovascular Disease
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N6-(4-Hydroxybenzyl)adenosine is a inhibitor of platelet aggregation induced in vitro by collagen and their activity range was demonstrated (IC50: 6.77-141 μM).
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- HY-Y1630S
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para-fluoronitrobenzene-d4; p-Fluoronitrobenzene-d4; p-Nitrofluorobenzene-d4
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Isotope-Labeled Compounds
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Others
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NSC 10281-d4 is the deuterium labeled NSC 10281[1].
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- HY-W145693
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- HY-D2286
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Fluorescent Dye
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Others
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HBT-Fl-BnB is a fluorescent probe for the ratiometric detection of ONOO - in vitro and in vivo. HBT-Fl-BnB consists of an HBT core with Fl groups at the ortho and para positions responding to the zwitterionic excited-state intramolecular proton-transfer (zwitterionic ESIPT) process and a boronic acid pinacol ester with dual roles that block the zwitterionic ESIPT and recognize ONOO - .
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- HY-155336
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- HY-117289
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Others
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Others
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AKOS B018304 is an arylalkylidene derivative, with polar substitution at para-position.
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- HY-I0447A
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4-Aminosalicylic acid sodium salt dihydrate
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Bacterial
Antibiotic
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Infection
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Sodium 4-aminosalicylate (Sodium para-Aminosalicylic acid) dihydrate is para-aminosalicylic acid (PAS), a dihydrofolate reductase (DHFR) inhibitor and antituberculous agent. PAS is incorporated into the folate pathway via dihydropteroate synthase (DHPS) and dihydrofolate synthase (DHFS) to generate the hydroxydihydrofolate antimetabolite, which in turn inhibits DHFR enzyme activity .
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- HY-W134422
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Polyoxyethylene octylphenol ether
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Biochemical Assay Reagents
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Others
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Triton X-114 is a complex of three molecules formed by ortho-, meta-, and para-substitution of the benzene ring.
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- HY-106685
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CI 935
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Influenza Virus
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Infection
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Selenazofurin is an antiviral compound used against influenza A and influenza B viruses. Selenazofurin shows antiviral activity in cells against Measles, Para-3, Mumps, VV, HSV-2 with the ED50s of 3.7 μg/ml, 1.3 μg/ml, 8.0 μg/ml, 3.4 μg/ml, 4.3 μg/ml .
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- HY-D1199
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P2X Receptor
P2Y Receptor
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Inflammation/Immunology
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Blue FPG-A trisodium is a selective antagonist of P2X1 receptor and P2Y1 receptor with IC50 values of 35.5 μM and 2.6 μM, respectively. Blue FPG-A trisodium is a structural isomer of the components of Reactive Blue 2 (RB2) .
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- HY-N2982
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Influenza Virus
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Infection
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Caesalmin E is a natural cassane furanoditerpene with anti-Para3 (Parainfluenza virus type 3) virus activities .
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- HY-B0322
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Ro 4-2130
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Bacterial
Antibiotic
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Infection
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Sulfamethoxazole (Ro 4-2130) is a sulfonamide bacteriostatic antibiotic, used for bacterial infections. Sulfonamides is a competitive antagonists of para-aminobenzoic acid (PABA) .
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- HY-P10668
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Dengue virus
Flavivirus
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Infection
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Ac-EVKKQR-pNA is a competitive chromogenic para-nitroanilide substrate corresponding to the P6-P1 segment amino-terminal to the NS2B-NS3 cleavage site but with a more reactive, hydrolytically cleavable, para-nitroanilide at the P1’ position. Ac-EVKKQR-pNA is promising for research of dengue 2 virus and flavivirus virus infection .
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- HY-W007614
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3-Fluoro-para-anisaldehyde
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Biochemical Assay Reagents
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Others
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3-Fluoro-4-methoxybenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-I0447AR
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Bacterial
Antibiotic
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Infection
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Sodium 4-aminosalicylate (dihydrate) (Standard) is the analytical standard of Sodium 4-aminosalicylate (dihydrate). This product is intended for research and analytical applications. Sodium 4-aminosalicylate (Sodium para-Aminosalicylic acid) dihydrate is para-aminosalicylic acid (PAS), a dihydrofolate reductase (DHFR) inhibitor and antituberculous agent. PAS is incorporated into the folate pathway via dihydropteroate synthase (DHPS) and dihydrofolate synthase (DHFS) to generate the hydroxydihydrofolate antimetabolite, which in turn inhibits DHFR enzyme activity .
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- HY-162297
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Others
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Others
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4-(Sulfooxy)benzoic acid is a sulfated phenolic acid found in C. elegans. 4-(Sulfooxy)benzoic acid is a metabolite of ethyl para-hydroxybenzoate and several flavonoids .
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- HY-B0512S
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Bacterial
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Infection
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Sulfamerazine-d4 is a deuterium labeled Sulfamerazine. Sulfamerazine, a sulfonamide antibacterial, inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthesizes[1].
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- HY-B0322S1
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Antibiotic
Bacterial
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Infection
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Sulfamethoxazole- 13C6 is a 13C labeled Sulfamethoxazole. Sulfamethoxazole (Ro 4-2130) is a sulfonamide bacteriostatic antibiotic, used for bacterial infections. Sulfonamides is a competitive antagonist of para-aminobenzoic acid (PABA)[1].
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- HY-B0322R
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Bacterial
Antibiotic
|
Infection
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Sulfamethoxazole (Standard) is the analytical standard of Sulfamethoxazole. This product is intended for research and analytical applications. Sulfamethoxazole (Ro 4-2130) is a sulfonamide bacteriostatic antibiotic, used for bacterial infections. Sulfonamides is a competitive antagonists of para-aminobenzoic acid (PABA) .
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- HY-147808
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CXCR
HIV
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Infection
Inflammation/Immunology
Cancer
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CXCR4 antagonist 7 (Compound PARA-B) is a CXCR4 antagonist with the IC50 of 9.3 nM. CXCR4 antagonist 7 can be used for the research of HIV infection, inflammatory diseases, cancer, and WHIM syndrome .
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- HY-108069
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Potassium Channel
nAChR
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Neurological Disease
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Iptakalim hydrochloride, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholine receptor (nAChR) antagonist .
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- HY-157370
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Biochemical Assay Reagents
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Others
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Blood Enrichment Medium can be used for enrichment culture of pathogenic bacteria in blood. Blood Enrichment Medium ingredients include peptone, beef extract powder, NaCl, glucose, sodium citrate, para-aminobenzoic acid, magnesium sulfate, phenol red .
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- HY-76547S
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4-Methylbenzoic acid-d4
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Endogenous Metabolite
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Others
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p-Toluic acid-d4 is the deuterium labeled p-Toluic acid[1]. p-Toluic acid (4-Methylbenzoic acid) is a substituted benzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc.
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- HY-76547S1
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4-Methylbenzoic acid-d7
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Endogenous Metabolite
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Others
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p-Toluic acid-d7 is the deuterium labeled p-Toluic acid[1]. p-Toluic acid (4-Methylbenzoic acid) is a substituted benzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc.
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- HY-76547S2
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4-Methylbenzoic acid-d3
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Endogenous Metabolite
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Others
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p-Toluic acid-d3 is the deuterium labeled p-Toluic acid[1]. p-Toluic acid (4-Methylbenzoic acid) is a substituted benzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc.
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- HY-W134422R
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Biochemical Assay Reagents
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Others
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Triton X-114 (Standard) is the analytical standard of Triton X-114. This product is intended for research and analytical applications. Triton X-114 is a complex of three molecules formed by ortho-, meta-, and para-substitution of the benzene ring.
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-
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- HY-129051
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CGP4540
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Parasite
Oxidative Phosphorylation
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Others
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Amoscanate (cgp4540) is phenyl isothiocyanate in which the hydrogen at the para-position has been replaced by a 4-nitroanilinyl group. Amoscanate is an anti-schistosomal agent. Amoscanate, as an isothiocyanate compound and uncoupler of oxidative phosphorylation, potently injures rodent ependyma .
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- HY-143452
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Tyrosinase
Bacterial
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Inflammation/Immunology
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MtTMPK-IN-4 (compound 2), a para-piperidine, is a potent mycobacterium tuberculosis thymidylate kinase (MtTMPK) inhibitor with an IC50 of 6.1 μM. MtTMPK-IN-4 is a potent tyrosinase inhibitor. MtTMPK-IN-4 is a potent antibacterial agent .
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- HY-161084
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c-Fms
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Neurological Disease
Cancer
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CSF1R-IN-18 (Compdound 16t), para-aniline derivative, is a colony-stimulating factor 1 receptor (CSF1R) inhibitor. CSF1R-IN-18 can be used for the research of cancers, CNS-diseases and bone diseases .
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- HY-156031
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Cholinesterase (ChE)
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Neurological Disease
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BChE-IN-19 (Compound 7b) is a para-substituted derivative of indone (7b) with inhibitory activity of butyryl cholinesterase (BChE) (IC50=0.04 μM). BChE-IN-19 improves cholinergic scheduling in the nervous system. BChE-IN-19 can be used against Alzheimer's disease .
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- HY-N10800
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1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-3,11-dioxanaphth[2,1-e]azulene-10,12-dione
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Others
|
Cancer
|
1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-3,11-dioxanaphth[2,1-e]azulene-10,12-dione is a kind of chemical constituents of Salvia miltiorrhiza f. alba. The dihydroisotanshinone with a para-quinone moiety shows cytotoxicity and anti-tumor activity .
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- HY-155817
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Histone Methyltransferase
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Others
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UNC7096 (compound 53) is a biotinylated affinity reagent. The phenyl ring of UNC7096 replaces the pyrimidine ring in UNC6934 (HY-145103) and introduces biotin at the para position of the phenyl ring, which has a high binding affinity to the NSD2-PWWP1 domain (Kd=46 nM). UNC7096 blocks the interaction between NSD2-PWWP1 and nucleosomal H3K36me2 by occupying the methyl-lysine binding pocket of NSD2-PWWP1. This binding is achieved by covalent binding through the formation of hydrogen bonds and a specific aromatic cage structure. UNC7096 can be used to capture proteins that interact with the NSD2-PWWP1 domain to further analyze the biological significance of these interactions .
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Cat. No. |
Product Name |
Type |
-
- HY-15928
-
para-nitrophenyl phosphate disodium
|
Chromogenic Substrates
|
PNPP (Para-nitrophenyl phosphate) disodium is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays.
|
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- HY-15632
-
|
DNA Stain
|
para-iodoHoechst 33258 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution .
|
-
- HY-D1045
-
-
- HY-D1045A
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DABCYL sodium; para-methyl red sodium
|
Fluorescent Dyes/Probes
|
Dabcyl acid sodium (DABCYL sodium) is a nonfluorescent chromophore and a quencher. Dabcyl acid sodium can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions .
|
-
- HY-D2286
-
|
Fluorescent Dyes/Probes
|
HBT-Fl-BnB is a fluorescent probe for the ratiometric detection of ONOO - in vitro and in vivo. HBT-Fl-BnB consists of an HBT core with Fl groups at the ortho and para positions responding to the zwitterionic excited-state intramolecular proton-transfer (zwitterionic ESIPT) process and a boronic acid pinacol ester with dual roles that block the zwitterionic ESIPT and recognize ONOO - .
|
Cat. No. |
Product Name |
Type |
-
- HY-W134422
-
Polyoxyethylene octylphenol ether
|
Surfactants
|
Triton X-114 is a complex of three molecules formed by ortho-, meta-, and para-substitution of the benzene ring.
|
-
- HY-W007614
-
3-Fluoro-para-anisaldehyde
|
Biochemical Assay Reagents
|
3-Fluoro-4-methoxybenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W145693
-
|
Biochemical Assay Reagents
|
Difucosyl-para-lacto-N-hexaose II (DFpLNH II) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
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- HY-157370
-
|
Microbial Culture
|
Blood Enrichment Medium can be used for enrichment culture of pathogenic bacteria in blood. Blood Enrichment Medium ingredients include peptone, beef extract powder, NaCl, glucose, sodium citrate, para-aminobenzoic acid, magnesium sulfate, phenol red .
|
-
- HY-W134422R
-
|
Surfactants
|
Triton X-114 (Standard) is the analytical standard of Triton X-114. This product is intended for research and analytical applications. Triton X-114 is a complex of three molecules formed by ortho-, meta-, and para-substitution of the benzene ring.
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P10668
-
|
Dengue virus
Flavivirus
|
Infection
|
Ac-EVKKQR-pNA is a competitive chromogenic para-nitroanilide substrate corresponding to the P6-P1 segment amino-terminal to the NS2B-NS3 cleavage site but with a more reactive, hydrolytically cleavable, para-nitroanilide at the P1’ position. Ac-EVKKQR-pNA is promising for research of dengue 2 virus and flavivirus virus infection .
|
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- HY-P5373
-
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Peptides
|
Others
|
Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2 is a biological active peptide. (Structure-activity studies of thrombin receptor-tethered ligand SFLLRNP have revealed
the importance of the Phe-2-phenyl group in receptor recognition and the replacement of the
Phe-2 by para-fluorophenylalanine [(p-F)Phe] was found to enhance its activity)
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-W145693
-
-
-
- HY-N2982
-
-
-
- HY-N10800
-
1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-3,11-dioxanaphth[2,1-e]azulene-10,12-dione
|
Structural Classification
Terpenoids
Labiatae
Source classification
Samanea saman (Jacq.) Merr.
Diterpenoids
Plants
|
Others
|
1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-3,11-dioxanaphth[2,1-e]azulene-10,12-dione is a kind of chemical constituents of Salvia miltiorrhiza f. alba. The dihydroisotanshinone with a para-quinone moiety shows cytotoxicity and anti-tumor activity .
|
-
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-Y1630S
-
|
NSC 10281-d4 is the deuterium labeled NSC 10281[1].
|
-
-
- HY-B0512S
-
|
Sulfamerazine-d4 is a deuterium labeled Sulfamerazine. Sulfamerazine, a sulfonamide antibacterial, inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthesizes[1].
|
-
-
- HY-B0322S1
-
|
Sulfamethoxazole- 13C6 is a 13C labeled Sulfamethoxazole. Sulfamethoxazole (Ro 4-2130) is a sulfonamide bacteriostatic antibiotic, used for bacterial infections. Sulfonamides is a competitive antagonist of para-aminobenzoic acid (PABA)[1].
|
-
-
- HY-76547S1
-
|
p-Toluic acid-d7 is the deuterium labeled p-Toluic acid[1]. p-Toluic acid (4-Methylbenzoic acid) is a substituted benzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc.
|
-
-
- HY-W739835
-
|
Para Red-d4 is the deuterium labeled Para Red .
|
-
-
- HY-W750432
-
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Para red-d6 is a deuterated labeled Para red-d6 .
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-
-
- HY-76547S
-
|
p-Toluic acid-d4 is the deuterium labeled p-Toluic acid[1]. p-Toluic acid (4-Methylbenzoic acid) is a substituted benzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc.
|
-
-
- HY-76547S2
-
|
p-Toluic acid-d3 is the deuterium labeled p-Toluic acid[1]. p-Toluic acid (4-Methylbenzoic acid) is a substituted benzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc.
|
-
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