Search Result
Results for "
phospholipid bilayers
" in MedChemExpress (MCE) Product Catalog:
28
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-109541
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DMPC; Dimyristoyl phosphatidylcholine
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Liposome
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Others
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1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine is used for the study of lipid monolayers and bilayers .
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-
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- HY-130462
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POPC
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Liposome
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Others
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1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers .
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-
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- HY-D1425
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9-(2,2-Dicyanovinyl)julolidine
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Fluorescent Dye
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Others
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DCVJ (9-(2,2-Dicyanovinyl)julolidine), a molecular rotor and unique fluorescent dye, binds to tubulin and actin, and increases its fluorescence intensity drastically upon polymerization. DCVJ also binds to phospholipid bilayers and increases its fluorescence intensity. DCVJ can detect the kinetic process of degranulation of mast cells .
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- HY-W040268
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Endogenous Metabolite
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Metabolic Disease
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1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine is a phospholipid that is a major component of the lipid bilayer that surrounds cells and provides stability to the membrane.
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-
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- HY-W441013
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Liposome
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Others
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DSPE-PEG-NHS, MW 1000 is an amine reactive phospholipid. The reaction between NHS esters and amines forms a stable amide bond. The polymer is amphiphilic and capable of forming micelles or lipid bilayer in aqueous solution.
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-
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- HY-W590535
-
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1,2-DNPC;
1,2-Dinonadecanoyl-sn-glycero-3-phosphocholine
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Liposome
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Cancer
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19:0 PC is a saturated phospholipid that has been used as a standard for the quantification of phosphatidylcholines in human synovial fluid. It has also been used to study dynamics of lipid bilayer phase transition.
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- HY-153725
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Liposome
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Cancer
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17:1 Lyso PC is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .
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- HY-W591449
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Liposome
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Cancer
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DOPE-PEG-Azide, MW 2000 is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .
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- HY-W440991
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Liposome
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Cancer
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DOPE-PEG-Amine (MW 2000) is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelle formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form a triazole ring.
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- HY-125385
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Endogenous Metabolite
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Metabolic Disease
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Sulforhodamine 101 DHPE is a fluorescent probe made from the conjugation of the phospholipid 1,2-dipalmitoyl-sn-glycero-3-PE to sulforhodamine 101, a red fluorescent dye that displays excitation/emission spectra of 586/605 nm, respectively. It integrates into phospholipid bilayers and has been used for imaging of solid supported lipid bilayers, detection of protein-ligand binding on bilayers, and to monitor colocalization of lipid probes in liposomes via resonance energy transfer (RET).
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- HY-W441017
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Liposome
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Others
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DSPE-SPDP is a phospholipid molecule. DSPE-SPDP can orient itself to form lipid bilayer in water. DSPE-SPDP can be used for the research of various biochemical .
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- HY-141571
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Liposome
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Others
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DOPG sodium is a phospholipid containing oleic acid (18:1) inserted at the sn-1 and sn-2 positions. It can form a lipid bilayer in an aqueous solution and is used in the generation of micelles, liposomes, and other artificial membranes.
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- HY-143202
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Liposome
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Others
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DPhPC is a derivative of phosphatidylcholine (PC) used to synthesize bilayer vesicle phospholipids. DPhPC bilayer membranes do not leak ions in the absence of pores or ion channels, so they are often used to study the activity of ion channels and the regulation of membrane potential. Nanoliposomes (NTG) prepared based on DPhPC can improve the bioavailability of nitric oxide (NO) and have effective anti-inflammatory effects .
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- HY-W441007
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Liposome
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Inflammation/Immunology
Cancer
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DSPE-MAL is a thiol reactive a phospholipid compound. DSPE-MAL has two saturated fatty acids and can self-assemble in water to form lipid bilayer. DSPE-MAL can be used to prepare liposomes as agent nanocarrier .
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- HY-40118
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Boc-L-proline methyl ester
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Liposome
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Others
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Boc-Pro-OMe (Boc-L-proline methyl ester) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
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- HY-164579
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Liposome
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Others
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NH2-GG-DSPE is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
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- HY-W440833
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Biochemical Assay Reagents
Liposome
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Others
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DSPE-PEG-Azide, MW 3400 is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelles formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form triazole bond. Reagent grade, for research use only.
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- HY-W440896
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Liposome
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Others
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DSPE-PEG-SH, MW 2000 is a pegylated phospholipid with thiol group which is reactive with maleimide to form a covalent thioether linkage. The amphiphatic polymer can form lipid bilayer in aqueous solution and be used to encapsulate agents for drug delivery system, such as mRNA vaccine.
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- HY-W440928
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Biochemical Assay Reagents
Liposome
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Others
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DSPE-PEG-DBCO, MW 5000 is a phospholipid polyPEG which can self-assemble in water to form lipid bilayer. The polymer can be used to prepare liposomes as drug carrier to deliver nutrients/therpeutic agents, such as mRNA or DNA. Reagent grade, for research use only.
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- HY-157678
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Liposome
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Others
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1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
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- HY-W440921
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Liposome
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Others
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DSPE-PEG-Rhodamine, MW 5000 is a phospholipid polyPEG with red fluorescent. The polymer can form lipid bilayer and be used to prepare nanoparticles or liposomes for targeted drug delivery. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
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- HY-W440920
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Liposome
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Others
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DSPE-PEG-Rhodamine, MW 3400 is a phospholipid polyPEG with red fluorescent. The polymer can form lipid bilayer and be used to prepare nanoparticles or liposomes for targeted drug delivery. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
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- HY-167545
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POPE
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Liposome
Biochemical Assay Reagents
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Others
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1-Palmitoyl-2-oleoylphosphatidylethanolamine (POPE) is a PE-based synthetic phospholipid that can intercalate with other amphiphilic molecules to form stable bilayers at physiological pH. 1-Palmitoyl-2-oleoylphosphatidylethanolamine can be used in drug delivery research .
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- HY-157624
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18:0-22:6 PE
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Liposome
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Others
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1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine (18:0-22:6 PE) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
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- HY-W440909
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Liposome
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Others
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DSPE-PEG-Cy3, MW 3400 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-W440910
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Liposome
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Others
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DSPE-PEG-Cy3, MW 5000 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-P10564
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Bacterial
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Infection
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Pardaxin P 4 is an antimicrobial peptide found in the secretions of Red Sea Moses sole. Pardaxin P 4 acts as a biomembrane perforator that can interact with phospholipid bilayers of different compositions and induce cytotoxicity and pore formation. Pardaxin P 4 can be used in the research of antimicrobial drugs .
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- HY-W440913
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Liposome
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Others
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DSPE-PEG-Cy5, MW 5000 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-W440912
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Liposome
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Others
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DSPE-PEG-Cy5, MW 3400 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-W440834
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Biochemical Assay Reagents
Liposome
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Others
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DSPE-PEG-Azide, MW 5000 is a click chemistry reactive phospholipid polyPEG which forms lipid bilayer or micelles in an aqueous solution. The polymer can be used to prepare liposomes or nanoparticles used for delivering nutrients or therapeutic agents, for example mRNA or DNA vaccine. Reagent grade, for research use only.
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- HY-W440919
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Liposome
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Others
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DSPE-PEG-Rhodamine, MW 2000 is a dye functionalized phospholipid. The amphiphilic polymer can form lipid bilayer in water and be used to encapsulate therapeutic agents, such as liposomal anticancer drug or mRNA vaccine. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
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- HY-165975
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(2S)-3-Keto-C6-dihydrosphingosine hydrochloride
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Liposome
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Others
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(2S)-3-Keto sphinganine (d6:0) ((2S)-3-Keto-C6-dihydrosphingosine) hydrochloride is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
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- HY-D0986
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Fluorescent Dye
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Others
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TMA-DPH is a hydrophobic fluorescent membrane probe (Ex=355 nm; Em=430 nm). TMA-DPH is able to anchor on the cell surface and localize to different regions of the phospholipid bilayer. By analyzing the fluorescence polarization values of TMA-DPH in the plasma membrane and membrane substructures, the fluidity of the cell membrane can be determined .
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- HY-W441011
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Liposome
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Neurological Disease
Inflammation/Immunology
Cancer
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DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .
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- HY-W441003
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Biochemical Assay Reagents
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Others
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DSPE-PEG-IA, MW 2000 is a thiol reactive phospholipid polyPEG. The iodoacetyll group is reactive with thiol to produce a thioether linkage. The polymer can self-assemble in water to form lipid bilayer and can be used to encapsulate drugs in targeted delivery application, such as liposomal doxorubicin as an anti cancer drug or mRNA vaccine. Reagent grade, for research use only.
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-
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- HY-W440905
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Biochemical Assay Reagents
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Others
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DSPE-PEG-Vinylsulfone, MW 2000 is a phospholipid PEG which can self-assemble to form lipid bilayer in water. The polymer can be used to encapsulate therapeutics, such as nucleic acid (mRNA/DNA) or protein, in drug delivery system. The vinyl sulfone is reactive with thiol molecule via thiol-ene reaction for bioconjugation. Reagent grade, for research use only.
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- HY-W440883
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Liposome
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Others
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DSPE-PEG-Ald, MW 2000 is a phospholipid polyPEG which can self-assemble to form lipid bilayer in aqueous solution. The polymer can be used to prepare liposome as a drug delivery vehicle for administration of drugs or nutrients, such as mRNA vaccines. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
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- HY-131640
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1,2-Didecanoyl-sn-glycero-3-phosphocholine
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Liposome
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Others
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1,2-Didecanoyl PC (1,2-Didecanoyl-sn-glycero-3-phosphocholine) is a phosphocholine that can be introduced into single-chain mean field theory as a coarse-grained model of saturated phospholipids. The 1,2-Didecanoyl PC model can be used to estimate the free energy of compressive or tensile bilayers in stacks or multilayers and gives a reasonable estimate of the free energy .
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- HY-W440903
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Biochemical Assay Reagents
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Others
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DSPE-PEG-DBCO, MW 2000 is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond. Reagent grade, for research use only.
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- HY-W440926
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Biochemical Assay Reagents
Liposome
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Others
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DSPE-PEG-DBCO, MW 2000 is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond. Reagent grade, for research use only.
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- HY-125619
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Liposome
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Others
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1,2-dioctanoyl-sn-glycero-3-phosphocholine, is a phospholipid commonly used as a component of liposome formulations and drug delivery systems. 1,2-dioctanoyl-sn-glycero-3-phosphocholine has unique chemical properties that allow it to form stable bilayers and vesicles, allowing drug encapsulation and delivery to specific targets in the body. It acts as a stabilizer and emulsifier, which can improve the solubility and bioavailability of drugs.
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- HY-P10035
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Amyloid-β
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Neurological Disease
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β Amyloid(28-35) human is a β-amyloid peptide (Abeta), a lipid-induced amyloid core fragment. β Amyloid oligomers are neurotoxic, and β Amyloid(28-35) human can interact with neuronal membranes, regulate secondary structure and neurotoxicity, and cause Alzheimer's disease. β Amyloid(28-35) human has anisotropic effects on the acidic phospholipid DPH, resulting in enhanced internal fluidity of lipid membrane bilayers .
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- HY-165029
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PLPC
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Liposome
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Others
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1-Palmitoyl-2-linoleoyl-sn-glycero-3-PC (PLPC) is a phospholipid used as a major component in lipid bilayer system models. 1-Palmitoyl-2-linoleoyl-sn-glycero-3-PC can serve as an untreated control, mixed with oxidized lipids such as 1-palmitoyl-2-(13-hydroxy-9,11-octadecanedienoyl)-lecithin (OHPLPC) and 1-palmitoyl-2-(13-hydroperoxy-9,11-octadecanedienoyl)-lecithin (HpPLPC), to study the effects of oxidation on membrane properties .
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- HY-W440752
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Liposome
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Cancer
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BP Lipid 113 is an ionizable lipid analogous to SM-102. It can be used to prepare liposome or lipid nanoparticles.
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- HY-W800749
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Liposome
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Cancer
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BP Lipid 223 is an pentanolamine lipid (Compound 7) from patent WO2017075531A with both ester bonds located adjacent to C6 relative to the amine head. The introduction of ester linkages can improve the clearance of the lipid in the liver. This compound is analgous to ALC-0315. The lipid can be used to prepare mRNA nanocarriers with good balance of delivery efficiency and pharmakokinetics as well as rapid lipid clearance profile.
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- HY-W800786
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N-MCC-PE
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Liposome
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Cancer
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16:0 PE MCC is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two palmitic acid tails and a maleimide group.
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-
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- HY-W440711
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Liposome
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Cancer
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Cholesterol-PEG-Biotin (MW 2000) is a pegylated lipids which has strong binding to avidin or streptavidin.
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-
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- HY-W800734
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MPPC; PC(14:0/16:0)
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Liposome
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Cancer
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1-Myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine (MPPC) is an asymmetrical phosphatidylcholine containing a myristic acid (14:0) at the sn-1 position and a palmitic acid (16:0) at the sn-2 position. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-W800777
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Liposome
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Cancer
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6-(3-Hydroxypropylamino)hexyl 2-hexyldecanoate is an ionizable lipid which can be used to make ALC-0315. The lipid has an ester bond adjacent to C6 relative to the amine nitrogen. The introduction of ester linkages can improve the clearance of the lipid in the liver.
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-
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- HY-W800785
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1-palMitoyl-2-(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine
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Liposome
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Cancer
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16:0-23:2 Diyne PC is a phospholipase-mediated hydrolyzed phosphocoline with palmitic acid (16:0) and Pentacosa-10,12-diynoic acid for tails.
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- HY-W440706
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Liposome
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Cancer
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Cholesterol-PEG-alcohol (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. The amine can react with an activated NHS ester to form a stable amide bond.
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- HY-W800787
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Liposome
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Cancer
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18:1 PE MCC is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two oleic acid tails and a maleimide group.
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- HY-W440719
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Liposome
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Cancer
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Cholesterol-PEG-MAL (MW 2000) is a PEG derivative and can be used to prepare liposome or nanoparticle due to its ability to self-assemble in water. The maleimide moiety is reactive with thiol molecule to form a covalent thioether bond.
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- HY-W339838
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14:0 Lyso PG
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Liposome
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Cancer
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1-Myristoyl-2-hydroxy-sn-glycero-3-PG sodium is a lysophospholipid containing myristic acid (14:0) at the sn-1 position. It has been used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
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- HY-141615
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PDME; 16:0 Dimethyl PE
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Liposome
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Cancer
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1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine has been used in the generation of liposomes and monolayers for use in the study of membrane permeability and monolayer viscosity, respectively.
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- HY-W440748
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Liposome
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Cancer
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BP Lipid 109 is an amine lipid which has long (11 carbons) lipid tail on the primary ester. Both esters are located at C7 position and the head contains ethanolamine. It can be used to prepare liposome or lipid nanoparticles.
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- HY-W140488
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10:0 PE
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Liposome
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Cancer
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1,2-Didecanoyl-sn-glycero-3-phosphoethanolamine, a phospholipid, showes very promising P-gp inhibitory results at a concentration of 0.3 mM.
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- HY-W440694
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Liposome
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Cancer
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Cholesterol-PEG-Azide (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. Cholesterol-PEG-Azide (MW 2000) can be reacted with alkyne via CuAAC or SPAAC click chemistry.
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- HY-W800737
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Liposome
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Cancer
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BP Lipid 126 is an amino ionizable lipid (Compound 143) from patent WO2017201333A1 with ester bonds located at C8 and C7 position relative to nitrogen. The ester linkages are introduced to improve tissue clearance. The ethanolamine head can effectively enhance mRNA encapsulation. BP Lipid 126 can be used in the generation of liposomes.
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- HY-W343736
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1,3-DPPE; 1,3-Dipalmitoyl-sn-glycero-2-PE
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Liposome
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Cancer
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1,3-Dipalmitoyl-glycero-2-phosphoethanolamine is a phospholipid containing the saturated long-chain (16:0) stearic acid inserted at the sn-1 and sn-3 positions and PE at the sn-2 site. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-W800784
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Liposome
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Cancer
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23:2 Diyne PE [DC(8,9)PE] is a phospholipase-mediated hydrolyzed phosphocoline with palmitic acid (16:0) and Pentacosa-10,12-diynoic acid for tails.
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-
![23:2 Diyne PE [DC(8,9)PE]](//file.medchemexpress.eu/product_pic/hy-w800784.gif)
- HY-W440690
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Liposome
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Cancer
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Cholesterol-PEG-Amine (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles.
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- HY-138913
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Liposome
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Cancer
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2H-Cho-Arg (TFA) is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection.
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- HY-W440698
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Liposome
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Cancer
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Cholesterol-PEG-Acid (MW 2000) is a polydisperse PEG derivative which can be used to create liposome as drug carrier for delivering therapeutic agents into tissues.
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- HY-W340832
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Liposome
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Cancer
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18:1 Biotinyl Cap PE is a fluorescent lipid, which features a head group that has been altered to include biotinyl cap PE.
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- HY-W800778
-
|
|
Liposome
|
Cancer
|
|
Bis(2-butyloctyl) 10-oxononadecanedioate is an ionizable lipid-like compound containing four hydrophobic tails bound by esters. It can be used to build lipids for mRNA encapsulation and delivery.
|
-
- HY-W440743
-
|
|
Liposome
|
Cancer
|
|
BP Lipid 103 is an amine ionizable lipid analogous to SM-102. It can be used to prepare liposome or lipid nanoparticles.
|
-
- HY-W591913
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG-methoxy, MW 2000 is a PEG derivative which self-assembles in water to form micelle-like structure. The cholesterol tail can be used to encapsulate hydrophobic drugs while the PEG chain ehances the water solubility of the micelles.
|
-
- HY-160912
-
|
|
ELOVL
|
Cancer
|
|
ELOVL6-IN-5 (compound B) is an inhibitor of the elongase enzyme of long-chain fatty acid family 6 (ELOVL6). ELOVL6 is a rate-limiting enzyme for the elongation of saturated and monounsaturated long-chain fatty acids and is an effective target for inhibiting diabetes. ELOVL6-IN-5 reduces hepatic fatty acid levels in a mouse model of diet-induced obesity (DIO). However, ELOVL6 inhibition by ELOVL6-IN-5 did not improve insulin resistance .
|
-
- HY-115435
-
|
DMPS-Na; Dimyristoyl phosphatidylserine sodium
|
Liposome
|
Cancer
|
|
1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine sodium is an anionic phospholipid with myristic acid tails (14:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of liposome.
|
-
- HY-134174
-
|
|
Liposome
|
Cancer
|
|
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate is a phospholipid containing saturated palmitic acid (16:0) and monounsaturated oleic acid (18:1) inserted at the sn-1 and sn-2 positions, respectively. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
|
-
- HY-W440751
-
|
|
Liposome
|
Cancer
|
|
BP Lipid 112 is an amine lipid with two ester linkages at C6 and C7 position. The C6 ester has a long 11 carbons lipid tail. It can be used to prepare liposome or lipid nanoparticles.
|
-
- HY-W440727
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG-Vinylsulfone (MW 2000) is a thiol reactive polyPEG via thiol-ene reaction to form a thioether bond. It can self-assemble in water and is used to prepare liposome as drug vehicle for targeted delivery into tissues.
|
-
- HY-W440724
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG-Thiol (MW 3400) is an amphiphatic PEG derivative which forms micelles in water and can be used to prepare liposomes or nanoparticles for drug delivery system. The thiol moiety is reactive with maleimide to form a stable thioether bond.
|
-
- HY-W440981
-
|
1-Stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine
|
Liposome
|
Cancer
|
|
SPPC is a phospholipid with different length of fatty acid. The sn-1 position contains a stearic acid (18:0) while the sn-2 position is occupied by a palmitic acid (16:0).
|
-
- HY-W440803
-
|
|
Liposome
|
Cancer
|
|
BP Lipid 218 is an ionizable amine lipid with two identical ester tails adjacent to C6 position relative to amine.
|
-
- HY-W440800
-
|
|
Liposome
|
Cancer
|
|
BP Lipid 226 is an amino ionizable lipid analogous to ALC-0315. It can be used to prepare liposome or lipid nanoparticles.
|
-
- HY-W440820
-
|
|
Liposome
|
Cancer
|
|
Bis(bis(2-carboxyethyl)aminopropyl)methylamine is a symmetrical branched linker featuring three tertiary amines and four carboxylic acids. Each carboxylic acid is open to forming esters or amides. It can be used in developing lipid nanoparticles.
|
-
- HY-W440766
-
|
|
Liposome
|
Cancer
|
|
BP Lipid 209 is an amine lipid which has a 9-carbons lipid tail on the primary ester. Both esters are located at C8 and C10 position relative to the amine nitrogen. It can be used to prepare liposome or lipid nanoparticles.
|
-
- HY-W440957
-
|
PC(16:0/14:0); 1-palmitoyl-2-myristoyl-sn-glycero-3-phosphocholine
|
Liposome
|
Cancer
|
|
PMPC is a phosphatidylcholine with asymmetrical fatty acid. Palmitic acid occupies sn-1 position while myristic acid is placed at the sn-2 position.
|
-
- HY-W440958
-
|
PSPC; PC(16:0-18:0)
|
Liposome
|
Cancer
|
|
1-Palmitoyl-2-stearoyl-sn-glycero-3-phosphocholine is an assymetrical phospholipid containing saturated palmitic and stearic acid at the sn-1 and sn-2 position respectively. The phosphate group is attached to choline.
|
-
- HY-W440931
-
|
|
Liposome
|
Cancer
|
|
MPEG2000-DMG is a synthetic lipid comprised of polyPEG and dimyristoyl glycerol. It is used in the creation of lipid nanoparticles (LNPs) for mRNA vaccines.
|
-
- HY-W591461
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG-COOH, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal carboxylic acid can react with primary amine groups to form a stable amide bond.
|
-
- HY-W440985
-
|
1,2-dilauroyl-sn-glycero-3-phospho-L-serine
|
Liposome
|
Cancer
|
|
DLPS is an anionic phospholipid with lauric acid tails (12:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposome, or artificial membrane. Due to the medium size of fatty acid chain, DLPS is used to form thinner membranes/walls.
|
-
- HY-W440995
-
|
|
Liposome
|
Cancer
|
|
DOPE-PEG-Mal (MW 2000) is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. It is also reactive with thiol at pH 6.5 tp 7.5 to form a stable thioether bond.
|
-
- HY-W441005
-
|
|
Liposome
|
Cancer
|
|
Amino-Gly-Gly-DSPE (hydrochloride) is a specially modified phospholipid that has been used to synthesize liposomes. The terminal amine is reactive with an NHS ester compound or carboxylic acid molecule in the presence of activator, such as HATU or EDC.
|
-
- HY-W587499
-
|
|
Liposome
|
Cancer
|
|
2-Arachidonoyl-sn-glycero-3-phosphocholine is a phospholipid molecule that is a major component of the plasma membrane. It is a phospholipid molecule that is involved in the regulation of membrane fluidity, signal transduction, cell-cell communication, and mediator of inflammation.
|
-
- HY-W590536
-
|
1-Palmitoyl-2-Lauroyl-sn-glycero-3-Phosphatidylcholine; 1-Palmitoyl-2-Lauroyl-sn-glycero-3-Phosphocholine
|
Liposome
|
Cancer
|
|
1,2-PLPC is a phospholipid containing palmitoyl (16:0) and lauryl (12:0) acyl substituents at the sn-1 and sn-2 positions, respectively. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
|
-
- HY-W590538
-
|
|
Liposome
|
Cancer
|
|
HAPC-Chol is a cationic cholesterol that can be used as a component of lipoplexes complexes.
|
-
- HY-W590555
-
|
|
Liposome
|
Cancer
|
|
Thiol-PEG-DMG, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc.
|
-
- HY-W590593
-
|
|
Liposome
|
Cancer
|
|
mPEG-Cholesterol,MW 2000 is a PEG derivative which self-assembles in water to form micelle-like structure. The cholesterol tail can be used to encapsulate hydrophobic drugs while the PEG chain ehances the water solubility of the micelles.
|
-
- HY-W591332
-
|
|
Liposome
|
Cancer
|
|
DMPE-mPEG, MW 2000 is a PEGylated 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (14:0 PE) compound with a methyl group at the other end of the PEG chain. The PEG polymer exhibits amphiphatic behavior and helps to form stable micelles in an aqueous solution. It can be used to prepare nanoparticles or liposomes for targeted drug delivery applications.
|
-
- HY-W800733
-
|
1,2-Dilauroyl-sn-glycero-3-phosphorylglycerol; PG(12:0/12:0)
|
Liposome
|
Cancer
|
|
DLPG is a phospholipid containing lauric acid (12 chain fatty acid) inserted at the sn-1 and sn-2 positions. Its phosphate group is attached to glycerol. It is used in the generation of micelles, liposomes, and other artificial membranes.
|
-
- HY-W800788
-
|
|
Liposome
|
Cancer
|
|
18:1 MPB PE is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two oleic acid tails and a phenyl maleimide group.
|
-
- HY-W800789
-
|
|
Liposome
|
Cancer
|
|
16:0 MPB PE is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two palmitic acid tails and a phenyl maleimide group.
|
-
- HY-W800790
-
|
|
Liposome
|
Cancer
|
|
18:1 Caproylamine PE is a amine-functionalized lipid with a phosphoethanolamine linked to two oleic acid tails.
|
-
- HY-W800791
-
|
|
Liposome
|
Cancer
|
|
16:0 Caproylamine PE is an amide-functionalized lipid with a phosphoethanolamine linked to two palmitic acid tails.
|
-
- HY-W800792
-
|
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl)
|
Liposome
|
Cancer
|
|
18:1 Succinyl PE is a carboxylic acid-functionalized lipid with a two carbon linker to a phosphoethanolamine bound to two oleic acid tails.
|
-
- HY-W800793
-
|
1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl)
|
Liposome
|
Cancer
|
|
16:0 Succinyl PE is a carboxylic acid-functionalized lipid with a two carbon linker to a phosphoethanolamine bound to two palmitic acid tails.
|
-
- HY-W800794
-
|
DPPE-NG; 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(glutaryl)
|
Liposome
|
Cancer
|
|
16:0 Glutaryl PE is is a carboxylic acid-functionalized lipid with a three carbon linker to a phosphoethanolamine bound to two palmitic acid tails.
|
-
- HY-W800795
-
|
DOPE-NG; 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(dodecanoyl)
|
Liposome
|
Cancer
|
|
18:1 Dodecanyl PE is a carboxylic acid-functionalized lipid with a ten carbon linker to a phosphoethanolamine bound to two oleic acid tails.
|
-
- HY-W800796
-
|
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(biotinyl)
|
Liposome
|
Cancer
|
|
18:1 Biotinyl PE is a biotin-functionalized lipid attached to a phosphoethanolamine linked to two oleic acid groups.
|
-
- HY-W800797
-
|
1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(biotinyl)
|
Liposome
|
Cancer
|
|
16:0 Biotinyl PE is a biotin-functionalized lipid attached to a phosphoethanolamine linked to two palmitic acid groups.
|
-
- HY-W800798
-
|
1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(cyanur)
|
Liposome
|
Cancer
|
|
16:0 Cyanur PE is a cyanur-functionalized lipid attached to a phosphoethanolamine linked to two palmitic acid groups.
|
-
- HY-W800802
-
|
|
Liposome
|
Cancer
|
|
BP Lipid 227 is an ionizable lipid. It has primary esters at C5 position relative to the amine nitrogen. The primary lipid tail has an 8 carbon tail. BP Lipid 227 can be used in the generation of liposomes.
|
-
- HY-W800805
-
|
|
Liposome
|
Cancer
|
|
DOPE-Mal is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions with a terminal maliemide group. The maleimide group will react with a thiol group to form a covalent bond. The hydrophilic PEG spacer increases solubility in aqueous media.
|
-
- HY-W800812
-
|
|
Liposome
|
Cancer
|
|
BP Lipid 308 has a terminal tertiary amine group, a linoleic group, and a 4,4-bis(octyloxy)butanoic acid sodium salt tail. This compound can be useful for the building or modification of lipid nanoparticles.
|
-
- HY-W800825
-
|
|
Liposome
|
Cancer
|
|
Octadecanedioic Acid Mono-L-carnitine ester is a cationic lipid which may be used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Its terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond.
|
-
- HY-W800827
-
|
|
Liposome
|
Cancer
|
|
BP Lipid 229 is an amino ionizable lipid. It has primary esters at C7 position relative to the amine nitrogen. The primary lipid tail has 8 carbon tail. BP Lipid 229 can be used in the generation of liposomes.
|
-
- HY-W800841
-
|
|
Liposome
|
Cancer
|
|
BP Lipid 314 is an ionizable amino lipid featuring a dimethylamino head group, a carbamate linking to a central tertiary carbon with two other branches, a linoleate ester, and an aliphatic acetal ester.
|
-
- HY-W800843
-
|
|
Liposome
|
Cancer
|
|
tert-Butyl 3-(7-((undecan-3-yloxy)carbonyl)heptylamino)propylcarbamate is an aminolipid featuring a Boc-protected primary amine, a propylamine spacer attached to an octanoate chain and a C11 chain.
|
-
- HY-W800849
-
|
|
Liposome
|
Cancer
|
|
BP Lipid 315 is a cationic ionizable lipid ALC-0315 analogue featuring a Boc-protected primary amine, a central tertiary amine, and two ester tails located at the C8 position relative to the amine. One of these esters features a symmetrical branched C17 tail, while the other is an asymmetric C11 tail.
|
-
- HY-W590538A
-
|
|
Liposome
|
Others
|
|
HAPC-Chol is a cationic cholesterol that can be used as a component of lipoplexes complexes .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D0986
-
|
|
Fluorescent Dyes/Probes
|
|
TMA-DPH is a hydrophobic fluorescent membrane probe (Ex=355 nm; Em=430 nm). TMA-DPH is able to anchor on the cell surface and localize to different regions of the phospholipid bilayer. By analyzing the fluorescence polarization values of TMA-DPH in the plasma membrane and membrane substructures, the fluidity of the cell membrane can be determined .
|
| Cat. No. |
Product Name |
Type |
-
- HY-109541
-
|
DMPC; Dimyristoyl phosphatidylcholine
|
Drug Delivery
|
|
1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine is used for the study of lipid monolayers and bilayers .
|
-
- HY-130462
-
|
POPC
|
Drug Delivery
|
|
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers .
|
-
- HY-141571
-
|
|
Drug Delivery
|
|
DOPG sodium is a phospholipid containing oleic acid (18:1) inserted at the sn-1 and sn-2 positions. It can form a lipid bilayer in an aqueous solution and is used in the generation of micelles, liposomes, and other artificial membranes.
|
-
- HY-143202
-
|
|
Drug Delivery
|
|
DPhPC is a derivative of phosphatidylcholine (PC) used to synthesize bilayer vesicle phospholipids. DPhPC bilayer membranes do not leak ions in the absence of pores or ion channels, so they are often used to study the activity of ion channels and the regulation of membrane potential. Nanoliposomes (NTG) prepared based on DPhPC can improve the bioavailability of nitric oxide (NO) and have effective anti-inflammatory effects .
|
-
- HY-W441007
-
|
|
Drug Delivery
|
|
DSPE-MAL is a thiol reactive a phospholipid compound. DSPE-MAL has two saturated fatty acids and can self-assemble in water to form lipid bilayer. DSPE-MAL can be used to prepare liposomes as agent nanocarrier .
|
-
- HY-W440896
-
|
|
Drug Delivery
|
|
DSPE-PEG-SH, MW 2000 is a pegylated phospholipid with thiol group which is reactive with maleimide to form a covalent thioether linkage. The amphiphatic polymer can form lipid bilayer in aqueous solution and be used to encapsulate agents for drug delivery system, such as mRNA vaccine.
|
-
- HY-W441013
-
|
|
Drug Delivery
|
|
DSPE-PEG-NHS, MW 1000 is an amine reactive phospholipid. The reaction between NHS esters and amines forms a stable amide bond. The polymer is amphiphilic and capable of forming micelles or lipid bilayer in aqueous solution.
|
-
- HY-W441017
-
|
|
Drug Delivery
|
|
DSPE-SPDP is a phospholipid molecule. DSPE-SPDP can orient itself to form lipid bilayer in water. DSPE-SPDP can be used for the research of various biochemical .
|
-
- HY-W440833
-
|
|
Drug Delivery
|
|
DSPE-PEG-Azide, MW 3400 is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelles formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form triazole bond. Reagent grade, for research use only.
|
-
- HY-W440928
-
|
|
Drug Delivery
|
|
DSPE-PEG-DBCO, MW 5000 is a phospholipid polyPEG which can self-assemble in water to form lipid bilayer. The polymer can be used to prepare liposomes as drug carrier to deliver nutrients/therpeutic agents, such as mRNA or DNA. Reagent grade, for research use only.
|
-
- HY-W440921
-
|
|
Drug Delivery
|
|
DSPE-PEG-Rhodamine, MW 5000 is a phospholipid polyPEG with red fluorescent. The polymer can form lipid bilayer and be used to prepare nanoparticles or liposomes for targeted drug delivery. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
|
-
- HY-W440920
-
|
|
Drug Delivery
|
|
DSPE-PEG-Rhodamine, MW 3400 is a phospholipid polyPEG with red fluorescent. The polymer can form lipid bilayer and be used to prepare nanoparticles or liposomes for targeted drug delivery. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
|
-
- HY-167545
-
|
POPE
|
Drug Delivery
|
|
1-Palmitoyl-2-oleoylphosphatidylethanolamine (POPE) is a PE-based synthetic phospholipid that can intercalate with other amphiphilic molecules to form stable bilayers at physiological pH. 1-Palmitoyl-2-oleoylphosphatidylethanolamine can be used in drug delivery research .
|
-
- HY-W440909
-
|
|
Drug Delivery
|
|
DSPE-PEG-Cy3, MW 3400 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-W440910
-
|
|
Drug Delivery
|
|
DSPE-PEG-Cy3, MW 5000 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-W440913
-
|
|
Drug Delivery
|
|
DSPE-PEG-Cy5, MW 5000 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-W440912
-
|
|
Drug Delivery
|
|
DSPE-PEG-Cy5, MW 3400 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-W440834
-
|
|
Drug Delivery
|
|
DSPE-PEG-Azide, MW 5000 is a click chemistry reactive phospholipid polyPEG which forms lipid bilayer or micelles in an aqueous solution. The polymer can be used to prepare liposomes or nanoparticles used for delivering nutrients or therapeutic agents, for example mRNA or DNA vaccine. Reagent grade, for research use only.
|
-
- HY-W440919
-
|
|
Drug Delivery
|
|
DSPE-PEG-Rhodamine, MW 2000 is a dye functionalized phospholipid. The amphiphilic polymer can form lipid bilayer in water and be used to encapsulate therapeutic agents, such as liposomal anticancer drug or mRNA vaccine. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
|
-
- HY-W441011
-
|
|
Drug Delivery
|
|
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .
|
-
- HY-W441003
-
|
|
Drug Delivery
|
|
DSPE-PEG-IA, MW 2000 is a thiol reactive phospholipid polyPEG. The iodoacetyll group is reactive with thiol to produce a thioether linkage. The polymer can self-assemble in water to form lipid bilayer and can be used to encapsulate drugs in targeted delivery application, such as liposomal doxorubicin as an anti cancer drug or mRNA vaccine. Reagent grade, for research use only.
|
-
- HY-W440905
-
|
|
Drug Delivery
|
|
DSPE-PEG-Vinylsulfone, MW 2000 is a phospholipid PEG which can self-assemble to form lipid bilayer in water. The polymer can be used to encapsulate therapeutics, such as nucleic acid (mRNA/DNA) or protein, in drug delivery system. The vinyl sulfone is reactive with thiol molecule via thiol-ene reaction for bioconjugation. Reagent grade, for research use only.
|
-
- HY-W440903
-
|
|
Drug Delivery
|
|
DSPE-PEG-DBCO, MW 2000 is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond. Reagent grade, for research use only.
|
-
- HY-W440926
-
|
|
Drug Delivery
|
|
DSPE-PEG-DBCO, MW 2000 is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond. Reagent grade, for research use only.
|
-
- HY-125619
-
|
|
Drug Delivery
|
|
1,2-dioctanoyl-sn-glycero-3-phosphocholine, is a phospholipid commonly used as a component of liposome formulations and drug delivery systems. 1,2-dioctanoyl-sn-glycero-3-phosphocholine has unique chemical properties that allow it to form stable bilayers and vesicles, allowing drug encapsulation and delivery to specific targets in the body. It acts as a stabilizer and emulsifier, which can improve the solubility and bioavailability of drugs.
|
-
- HY-164160
-
|
DPPS
|
Drug Delivery
|
|
1,2-Dipalmitoyl-rac-glycero-3-phospho-L-serine (DPPS) is a phospholipid compound with good membrane-forming ability. 1,2-Dipalmitoyl-rac-glycero-3-phospho-L-serine can form stable and well-defined bilayers, which are suitable for the study of membrane dynamics. 1,2-Dipalmitoyl-rac-glycero-3-phospho-L-serine is often used to prepare liposomes for various applications in the biomedical field.
|
-
- HY-167813
-
|
|
Drug Delivery
|
|
1-O-Palmityl-2-O-methyl-rac-glycero-3-phosphocholine is a synthetic phospholipid analogue with activity in studying lipid interactions and membrane asymmetry. 1-O-Palmityl-2-O-methyl-rac-glycero-3-phosphocholine is used to explore the overall stability of lipid bilayers. 1-O-Palmityl-2-O-methyl-rac-glycero-3-phosphocholine is of great significance for the study of membrane structure and function.
|
-
- HY-167809
-
|
|
Drug Delivery
|
|
1-Palmitoyl-2-cholesterylcarbonoyl-sn-glycero-3-phosphocholine is a sterol-modified phospholipid with the activity of maintaining the stability of membrane bilayer structure and enhancing the liposome-mediated compound delivery process. 1-Palmitoyl-2-cholesterylcarbonoyl-sn-glycero-3-phosphocholine is widely used in biomedical applications to improve the delivery efficiency of compounds. 1-Palmitoyl-2-cholesterylcarbonoyl-sn-glycero-3-phosphocholine can also improve the release and distribution of compounds in cells.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-40118
-
|
Boc-L-proline methyl ester
|
Liposome
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Others
|
|
Boc-Pro-OMe (Boc-L-proline methyl ester) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
|
-
- HY-P10564
-
|
|
Bacterial
|
Infection
|
|
Pardaxin P 4 is an antimicrobial peptide found in the secretions of Red Sea Moses sole. Pardaxin P 4 acts as a biomembrane perforator that can interact with phospholipid bilayers of different compositions and induce cytotoxicity and pore formation. Pardaxin P 4 can be used in the research of antimicrobial drugs .
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-
- HY-P2697
-
|
Cys-Laminin A chain 2091-2108
|
Peptides
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Others
|
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PA22-2 (free acid) (Cys-Laminin A chain 2091-2108) is a peptide that supports neurite outgrowth and stimulates neuronal-like process formation. PA22-2 (free acid) can be used to culture human adenoid cystic carcinoma cells, and in the preparation of peptide-functionalized supported phospholipid bilayers .
|
-
- HY-P10035
-
|
|
Amyloid-β
|
Neurological Disease
|
|
β Amyloid(28-35) human is a β-amyloid peptide (Abeta), a lipid-induced amyloid core fragment. β Amyloid oligomers are neurotoxic, and β Amyloid(28-35) human can interact with neuronal membranes, regulate secondary structure and neurotoxicity, and cause Alzheimer's disease. β Amyloid(28-35) human has anisotropic effects on the acidic phospholipid DPH, resulting in enhanced internal fluidity of lipid membrane bilayers .
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| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
|
Classification |
-
- HY-W440833
-
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|
|
Azide
|
|
DSPE-PEG-Azide, MW 3400 is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelles formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form triazole bond. Reagent grade, for research use only.
|
-
- HY-W440834
-
|
|
|
Azide
|
|
DSPE-PEG-Azide, MW 5000 is a click chemistry reactive phospholipid polyPEG which forms lipid bilayer or micelles in an aqueous solution. The polymer can be used to prepare liposomes or nanoparticles used for delivering nutrients or therapeutic agents, for example mRNA or DNA vaccine. Reagent grade, for research use only.
|
-
- HY-W440694
-
|
|
|
Azide
|
|
Cholesterol-PEG-Azide (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. Cholesterol-PEG-Azide (MW 2000) can be reacted with alkyne via CuAAC or SPAAC click chemistry.
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| Cat. No. |
Product Name |
|
Classification |
-
- HY-109541
-
|
DMPC; Dimyristoyl phosphatidylcholine
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|
Phospholipids
|
|
1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine is used for the study of lipid monolayers and bilayers .
|
-
- HY-130462
-
|
POPC
|
|
Phospholipids
|
|
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers .
|
-
- HY-W040268
-
|
|
|
Phospholipids
|
|
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine is a phospholipid that is a major component of the lipid bilayer that surrounds cells and provides stability to the membrane.
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-
- HY-141571
-
|
|
|
Phospholipids
|
|
DOPG sodium is a phospholipid containing oleic acid (18:1) inserted at the sn-1 and sn-2 positions. It can form a lipid bilayer in an aqueous solution and is used in the generation of micelles, liposomes, and other artificial membranes.
|
-
- HY-143202
-
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|
|
Phospholipids
|
|
DPhPC is a derivative of phosphatidylcholine (PC) used to synthesize bilayer vesicle phospholipids. DPhPC bilayer membranes do not leak ions in the absence of pores or ion channels, so they are often used to study the activity of ion channels and the regulation of membrane potential. Nanoliposomes (NTG) prepared based on DPhPC can improve the bioavailability of nitric oxide (NO) and have effective anti-inflammatory effects .
|
-
- HY-W441013
-
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|
|
Pegylated Lipids
|
|
DSPE-PEG-NHS, MW 1000 is an amine reactive phospholipid. The reaction between NHS esters and amines forms a stable amide bond. The polymer is amphiphilic and capable of forming micelles or lipid bilayer in aqueous solution.
|
-
- HY-W590535
-
|
1,2-DNPC;
1,2-Dinonadecanoyl-sn-glycero-3-phosphocholine
|
|
Phospholipids
|
|
19:0 PC is a saturated phospholipid that has been used as a standard for the quantification of phosphatidylcholines in human synovial fluid. It has also been used to study dynamics of lipid bilayer phase transition.
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-
- HY-W591449
-
|
|
|
Pegylated Lipids
|
|
DOPE-PEG-Azide, MW 2000 is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .
|
-
- HY-W440991
-
|
|
|
Pegylated Lipids
|
|
DOPE-PEG-Amine (MW 2000) is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelle formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form a triazole ring.
|
-
- HY-W441017
-
|
|
|
Phospholipids
|
|
DSPE-SPDP is a phospholipid molecule. DSPE-SPDP can orient itself to form lipid bilayer in water. DSPE-SPDP can be used for the research of various biochemical .
|
-
- HY-W441007
-
|
|
|
Phospholipids
|
|
DSPE-MAL is a thiol reactive a phospholipid compound. DSPE-MAL has two saturated fatty acids and can self-assemble in water to form lipid bilayer. DSPE-MAL can be used to prepare liposomes as agent nanocarrier .
|
-
- HY-W440896
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG-SH, MW 2000 is a pegylated phospholipid with thiol group which is reactive with maleimide to form a covalent thioether linkage. The amphiphatic polymer can form lipid bilayer in aqueous solution and be used to encapsulate agents for drug delivery system, such as mRNA vaccine.
|
-
- HY-157678
-
|
|
|
Phospholipids
|
|
1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
|
-
- HY-W440921
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DSPE-PEG-Rhodamine, MW 5000 is a phospholipid polyPEG with red fluorescent. The polymer can form lipid bilayer and be used to prepare nanoparticles or liposomes for targeted drug delivery. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
|
-
- HY-W440920
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DSPE-PEG-Rhodamine, MW 3400 is a phospholipid polyPEG with red fluorescent. The polymer can form lipid bilayer and be used to prepare nanoparticles or liposomes for targeted drug delivery. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
|
-
- HY-157624
-
|
18:0-22:6 PE
|
|
Phospholipids
|
|
1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine (18:0-22:6 PE) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
|
-
- HY-W440909
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DSPE-PEG-Cy3, MW 3400 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-W440910
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DSPE-PEG-Cy3, MW 5000 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-W440913
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DSPE-PEG-Cy5, MW 5000 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-W440912
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DSPE-PEG-Cy5, MW 3400 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-W440919
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DSPE-PEG-Rhodamine, MW 2000 is a dye functionalized phospholipid. The amphiphilic polymer can form lipid bilayer in water and be used to encapsulate therapeutic agents, such as liposomal anticancer drug or mRNA vaccine. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
|
-
- HY-W441011
-
|
|
|
Phospholipids
|
|
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .
|
-
- HY-W440883
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG-Ald, MW 2000 is a phospholipid polyPEG which can self-assemble to form lipid bilayer in aqueous solution. The polymer can be used to prepare liposome as a drug delivery vehicle for administration of drugs or nutrients, such as mRNA vaccines. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
-
- HY-131640
-
|
1,2-Didecanoyl-sn-glycero-3-phosphocholine
|
|
Phospholipids
|
|
1,2-Didecanoyl PC (1,2-Didecanoyl-sn-glycero-3-phosphocholine) is a phosphocholine that can be introduced into single-chain mean field theory as a coarse-grained model of saturated phospholipids. The 1,2-Didecanoyl PC model can be used to estimate the free energy of compressive or tensile bilayers in stacks or multilayers and gives a reasonable estimate of the free energy .
|
-
- HY-125619
-
|
|
|
Phospholipids
|
|
1,2-dioctanoyl-sn-glycero-3-phosphocholine, is a phospholipid commonly used as a component of liposome formulations and drug delivery systems. 1,2-dioctanoyl-sn-glycero-3-phosphocholine has unique chemical properties that allow it to form stable bilayers and vesicles, allowing drug encapsulation and delivery to specific targets in the body. It acts as a stabilizer and emulsifier, which can improve the solubility and bioavailability of drugs.
|
-
- HY-165029
-
|
PLPC
|
|
Cationic Lipids
|
|
1-Palmitoyl-2-linoleoyl-sn-glycero-3-PC (PLPC) is a phospholipid used as a major component in lipid bilayer system models. 1-Palmitoyl-2-linoleoyl-sn-glycero-3-PC can serve as an untreated control, mixed with oxidized lipids such as 1-palmitoyl-2-(13-hydroxy-9,11-octadecanedienoyl)-lecithin (OHPLPC) and 1-palmitoyl-2-(13-hydroperoxy-9,11-octadecanedienoyl)-lecithin (HpPLPC), to study the effects of oxidation on membrane properties .
|
-
- HY-W440752
-
|
|
|
Cationic Lipids
|
|
BP Lipid 113 is an ionizable lipid analogous to SM-102. It can be used to prepare liposome or lipid nanoparticles.
|
-
- HY-W800749
-
|
|
|
Cationic Lipids
|
|
BP Lipid 223 is an pentanolamine lipid (Compound 7) from patent WO2017075531A with both ester bonds located adjacent to C6 relative to the amine head. The introduction of ester linkages can improve the clearance of the lipid in the liver. This compound is analgous to ALC-0315. The lipid can be used to prepare mRNA nanocarriers with good balance of delivery efficiency and pharmakokinetics as well as rapid lipid clearance profile.
|
-
- HY-W800786
-
|
N-MCC-PE
|
|
Phospholipids
|
|
16:0 PE MCC is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two palmitic acid tails and a maleimide group.
|
-
- HY-W440711
-
|
|
|
Pegylated Lipids
|
|
Cholesterol-PEG-Biotin (MW 2000) is a pegylated lipids which has strong binding to avidin or streptavidin.
|
-
- HY-W800734
-
|
MPPC; PC(14:0/16:0)
|
|
Phospholipids
|
|
1-Myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine (MPPC) is an asymmetrical phosphatidylcholine containing a myristic acid (14:0) at the sn-1 position and a palmitic acid (16:0) at the sn-2 position. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.
|
-
- HY-W800777
-
|
|
|
Cationic Lipids
|
|
6-(3-Hydroxypropylamino)hexyl 2-hexyldecanoate is an ionizable lipid which can be used to make ALC-0315. The lipid has an ester bond adjacent to C6 relative to the amine nitrogen. The introduction of ester linkages can improve the clearance of the lipid in the liver.
|
-
- HY-W800785
-
|
1-palMitoyl-2-(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine
|
|
Phospholipids
|
|
16:0-23:2 Diyne PC is a phospholipase-mediated hydrolyzed phosphocoline with palmitic acid (16:0) and Pentacosa-10,12-diynoic acid for tails.
|
-
- HY-W440706
-
|
|
|
Pegylated Lipids
|
|
Cholesterol-PEG-alcohol (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. The amine can react with an activated NHS ester to form a stable amide bond.
|
-
- HY-W800787
-
|
|
|
Phospholipids
|
|
18:1 PE MCC is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two oleic acid tails and a maleimide group.
|
-
- HY-W440719
-
|
|
|
Pegylated Lipids
|
|
Cholesterol-PEG-MAL (MW 2000) is a PEG derivative and can be used to prepare liposome or nanoparticle due to its ability to self-assemble in water. The maleimide moiety is reactive with thiol molecule to form a covalent thioether bond.
|
-
- HY-W339838
-
|
14:0 Lyso PG
|
|
Phospholipids
|
|
1-Myristoyl-2-hydroxy-sn-glycero-3-PG sodium is a lysophospholipid containing myristic acid (14:0) at the sn-1 position. It has been used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
|
-
- HY-141615
-
|
PDME; 16:0 Dimethyl PE
|
|
Phospholipids
|
|
1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine has been used in the generation of liposomes and monolayers for use in the study of membrane permeability and monolayer viscosity, respectively.
|
-
- HY-W440748
-
|
|
|
Cationic Lipids
|
|
BP Lipid 109 is an amine lipid which has long (11 carbons) lipid tail on the primary ester. Both esters are located at C7 position and the head contains ethanolamine. It can be used to prepare liposome or lipid nanoparticles.
|
-
- HY-W140488
-
|
10:0 PE
|
|
Phospholipids
|
|
1,2-Didecanoyl-sn-glycero-3-phosphoethanolamine, a phospholipid, showes very promising P-gp inhibitory results at a concentration of 0.3 mM.
|
-
- HY-W440694
-
|
|
|
Pegylated Lipids
|
|
Cholesterol-PEG-Azide (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. Cholesterol-PEG-Azide (MW 2000) can be reacted with alkyne via CuAAC or SPAAC click chemistry.
|
-
- HY-W800737
-
|
|
|
Cationic Lipids
|
|
BP Lipid 126 is an amino ionizable lipid (Compound 143) from patent WO2017201333A1 with ester bonds located at C8 and C7 position relative to nitrogen. The ester linkages are introduced to improve tissue clearance. The ethanolamine head can effectively enhance mRNA encapsulation. BP Lipid 126 can be used in the generation of liposomes.
|
-
- HY-W343736
-
|
1,3-DPPE; 1,3-Dipalmitoyl-sn-glycero-2-PE
|
|
Phospholipids
|
|
1,3-Dipalmitoyl-glycero-2-phosphoethanolamine is a phospholipid containing the saturated long-chain (16:0) stearic acid inserted at the sn-1 and sn-3 positions and PE at the sn-2 site. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
|
-
- HY-W800784
-
|
|
|
Phospholipids
|
|
23:2 Diyne PE [DC(8,9)PE] is a phospholipase-mediated hydrolyzed phosphocoline with palmitic acid (16:0) and Pentacosa-10,12-diynoic acid for tails.
|
-
- HY-W440690
-
|
|
|
Pegylated Lipids
|
|
Cholesterol-PEG-Amine (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles.
|
-
- HY-138913
-
|
|
|
Cholesterol
|
|
2H-Cho-Arg (TFA) is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection.
|
-
- HY-W440698
-
|
|
|
Pegylated Lipids
|
|
Cholesterol-PEG-Acid (MW 2000) is a polydisperse PEG derivative which can be used to create liposome as drug carrier for delivering therapeutic agents into tissues.
|
-
- HY-W340832
-
|
|
|
Phospholipids
|
|
18:1 Biotinyl Cap PE is a fluorescent lipid, which features a head group that has been altered to include biotinyl cap PE.
|
-
- HY-W800778
-
|
|
|
Cationic Lipids
|
|
Bis(2-butyloctyl) 10-oxononadecanedioate is an ionizable lipid-like compound containing four hydrophobic tails bound by esters. It can be used to build lipids for mRNA encapsulation and delivery.
|
-
- HY-W440743
-
|
|
|
Cationic Lipids
|
|
BP Lipid 103 is an amine ionizable lipid analogous to SM-102. It can be used to prepare liposome or lipid nanoparticles.
|
- HY-W591913
-
|
|
|
Pegylated Lipids
|
|
Cholesterol-PEG-methoxy, MW 2000 is a PEG derivative which self-assembles in water to form micelle-like structure. The cholesterol tail can be used to encapsulate hydrophobic drugs while the PEG chain ehances the water solubility of the micelles.
|
- HY-115435
-
|
DMPS-Na; Dimyristoyl phosphatidylserine sodium
|
|
Phospholipids
|
|
1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine sodium is an anionic phospholipid with myristic acid tails (14:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of liposome.
|
- HY-134174
-
|
|
|
Phospholipids
|
|
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate is a phospholipid containing saturated palmitic acid (16:0) and monounsaturated oleic acid (18:1) inserted at the sn-1 and sn-2 positions, respectively. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
|
- HY-W440751
-
|
|
|
Cationic Lipids
|
|
BP Lipid 112 is an amine lipid with two ester linkages at C6 and C7 position. The C6 ester has a long 11 carbons lipid tail. It can be used to prepare liposome or lipid nanoparticles.
|
- HY-W440727
-
|
|
|
Pegylated Lipids
|
|
Cholesterol-PEG-Vinylsulfone (MW 2000) is a thiol reactive polyPEG via thiol-ene reaction to form a thioether bond. It can self-assemble in water and is used to prepare liposome as drug vehicle for targeted delivery into tissues.
|
- HY-W440724
-
|
|
|
Pegylated Lipids
|
|
Cholesterol-PEG-Thiol (MW 3400) is an amphiphatic PEG derivative which forms micelles in water and can be used to prepare liposomes or nanoparticles for drug delivery system. The thiol moiety is reactive with maleimide to form a stable thioether bond.
|
- HY-W440981
-
|
1-Stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine
|
|
Phospholipids
|
|
SPPC is a phospholipid with different length of fatty acid. The sn-1 position contains a stearic acid (18:0) while the sn-2 position is occupied by a palmitic acid (16:0).
|
- HY-W440803
-
|
|
|
Cationic Lipids
|
|
BP Lipid 218 is an ionizable amine lipid with two identical ester tails adjacent to C6 position relative to amine.
|
- HY-W440800
-
|
|
|
Cationic Lipids
|
|
BP Lipid 226 is an amino ionizable lipid analogous to ALC-0315. It can be used to prepare liposome or lipid nanoparticles.
|
- HY-W440820
-
|
|
|
Cationic Lipids
|
|
Bis(bis(2-carboxyethyl)aminopropyl)methylamine is a symmetrical branched linker featuring three tertiary amines and four carboxylic acids. Each carboxylic acid is open to forming esters or amides. It can be used in developing lipid nanoparticles.
|
- HY-W440766
-
|
|
|
Cationic Lipids
|
|
BP Lipid 209 is an amine lipid which has a 9-carbons lipid tail on the primary ester. Both esters are located at C8 and C10 position relative to the amine nitrogen. It can be used to prepare liposome or lipid nanoparticles.
|
- HY-W440957
-
|
PC(16:0/14:0); 1-palmitoyl-2-myristoyl-sn-glycero-3-phosphocholine
|
|
Phospholipids
|
|
PMPC is a phosphatidylcholine with asymmetrical fatty acid. Palmitic acid occupies sn-1 position while myristic acid is placed at the sn-2 position.
|
- HY-W440958
-
|
PSPC; PC(16:0-18:0)
|
|
Phospholipids
|
|
1-Palmitoyl-2-stearoyl-sn-glycero-3-phosphocholine is an assymetrical phospholipid containing saturated palmitic and stearic acid at the sn-1 and sn-2 position respectively. The phosphate group is attached to choline.
|
- HY-W440931
-
|
|
|
Pegylated Lipids
|
|
MPEG2000-DMG is a synthetic lipid comprised of polyPEG and dimyristoyl glycerol. It is used in the creation of lipid nanoparticles (LNPs) for mRNA vaccines.
|
- HY-W591461
-
|
|
|
Pegylated Lipids
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DSPE-PEG-COOH, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal carboxylic acid can react with primary amine groups to form a stable amide bond.
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- HY-W440985
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1,2-dilauroyl-sn-glycero-3-phospho-L-serine
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Phospholipids
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DLPS is an anionic phospholipid with lauric acid tails (12:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposome, or artificial membrane. Due to the medium size of fatty acid chain, DLPS is used to form thinner membranes/walls.
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- HY-W440995
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Pegylated Lipids
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DOPE-PEG-Mal (MW 2000) is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. It is also reactive with thiol at pH 6.5 tp 7.5 to form a stable thioether bond.
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- HY-W441005
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Phospholipids
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Amino-Gly-Gly-DSPE (hydrochloride) is a specially modified phospholipid that has been used to synthesize liposomes. The terminal amine is reactive with an NHS ester compound or carboxylic acid molecule in the presence of activator, such as HATU or EDC.
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- HY-W587499
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Phospholipids
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2-Arachidonoyl-sn-glycero-3-phosphocholine is a phospholipid molecule that is a major component of the plasma membrane. It is a phospholipid molecule that is involved in the regulation of membrane fluidity, signal transduction, cell-cell communication, and mediator of inflammation.
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- HY-W590536
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1-Palmitoyl-2-Lauroyl-sn-glycero-3-Phosphatidylcholine; 1-Palmitoyl-2-Lauroyl-sn-glycero-3-Phosphocholine
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Phospholipids
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1,2-PLPC is a phospholipid containing palmitoyl (16:0) and lauryl (12:0) acyl substituents at the sn-1 and sn-2 positions, respectively. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-W590538
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Cholesterol
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HAPC-Chol is a cationic cholesterol that can be used as a component of lipoplexes complexes.
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- HY-W590555
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Pegylated Lipids
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Thiol-PEG-DMG, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc.
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- HY-W590593
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Pegylated Lipids
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mPEG-Cholesterol,MW 2000 is a PEG derivative which self-assembles in water to form micelle-like structure. The cholesterol tail can be used to encapsulate hydrophobic drugs while the PEG chain ehances the water solubility of the micelles.
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- HY-W591332
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Pegylated Lipids
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DMPE-mPEG, MW 2000 is a PEGylated 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (14:0 PE) compound with a methyl group at the other end of the PEG chain. The PEG polymer exhibits amphiphatic behavior and helps to form stable micelles in an aqueous solution. It can be used to prepare nanoparticles or liposomes for targeted drug delivery applications.
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- HY-W800733
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1,2-Dilauroyl-sn-glycero-3-phosphorylglycerol; PG(12:0/12:0)
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Phospholipids
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DLPG is a phospholipid containing lauric acid (12 chain fatty acid) inserted at the sn-1 and sn-2 positions. Its phosphate group is attached to glycerol. It is used in the generation of micelles, liposomes, and other artificial membranes.
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- HY-W800788
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Phospholipids
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18:1 MPB PE is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two oleic acid tails and a phenyl maleimide group.
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- HY-W800789
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Phospholipids
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16:0 MPB PE is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two palmitic acid tails and a phenyl maleimide group.
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- HY-W800790
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Phospholipids
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18:1 Caproylamine PE is a amine-functionalized lipid with a phosphoethanolamine linked to two oleic acid tails.
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- HY-W800791
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Phospholipids
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16:0 Caproylamine PE is an amide-functionalized lipid with a phosphoethanolamine linked to two palmitic acid tails.
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- HY-W800792
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1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl)
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Phospholipids
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18:1 Succinyl PE is a carboxylic acid-functionalized lipid with a two carbon linker to a phosphoethanolamine bound to two oleic acid tails.
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- HY-W800793
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1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl)
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Phospholipids
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16:0 Succinyl PE is a carboxylic acid-functionalized lipid with a two carbon linker to a phosphoethanolamine bound to two palmitic acid tails.
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- HY-W800794
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DPPE-NG; 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(glutaryl)
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Phospholipids
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16:0 Glutaryl PE is is a carboxylic acid-functionalized lipid with a three carbon linker to a phosphoethanolamine bound to two palmitic acid tails.
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- HY-W800795
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DOPE-NG; 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(dodecanoyl)
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Phospholipids
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18:1 Dodecanyl PE is a carboxylic acid-functionalized lipid with a ten carbon linker to a phosphoethanolamine bound to two oleic acid tails.
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- HY-W800796
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1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(biotinyl)
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Phospholipids
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18:1 Biotinyl PE is a biotin-functionalized lipid attached to a phosphoethanolamine linked to two oleic acid groups.
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- HY-W800797
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1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(biotinyl)
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Phospholipids
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16:0 Biotinyl PE is a biotin-functionalized lipid attached to a phosphoethanolamine linked to two palmitic acid groups.
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- HY-W800798
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1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(cyanur)
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Phospholipids
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16:0 Cyanur PE is a cyanur-functionalized lipid attached to a phosphoethanolamine linked to two palmitic acid groups.
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- HY-W800802
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Cationic Lipids
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BP Lipid 227 is an ionizable lipid. It has primary esters at C5 position relative to the amine nitrogen. The primary lipid tail has an 8 carbon tail. BP Lipid 227 can be used in the generation of liposomes.
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- HY-W800805
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Phospholipids
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DOPE-Mal is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions with a terminal maliemide group. The maleimide group will react with a thiol group to form a covalent bond. The hydrophilic PEG spacer increases solubility in aqueous media.
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- HY-W800812
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Cationic Lipids
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BP Lipid 308 has a terminal tertiary amine group, a linoleic group, and a 4,4-bis(octyloxy)butanoic acid sodium salt tail. This compound can be useful for the building or modification of lipid nanoparticles.
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- HY-W800825
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Cationic Lipids
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Octadecanedioic Acid Mono-L-carnitine ester is a cationic lipid which may be used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Its terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond.
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- HY-W800827
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Cationic Lipids
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BP Lipid 229 is an amino ionizable lipid. It has primary esters at C7 position relative to the amine nitrogen. The primary lipid tail has 8 carbon tail. BP Lipid 229 can be used in the generation of liposomes.
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- HY-W800841
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Cationic Lipids
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BP Lipid 314 is an ionizable amino lipid featuring a dimethylamino head group, a carbamate linking to a central tertiary carbon with two other branches, a linoleate ester, and an aliphatic acetal ester.
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- HY-W800843
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Cationic Lipids
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tert-Butyl 3-(7-((undecan-3-yloxy)carbonyl)heptylamino)propylcarbamate is an aminolipid featuring a Boc-protected primary amine, a propylamine spacer attached to an octanoate chain and a C11 chain.
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- HY-W800849
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Cationic Lipids
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BP Lipid 315 is a cationic ionizable lipid ALC-0315 analogue featuring a Boc-protected primary amine, a central tertiary amine, and two ester tails located at the C8 position relative to the amine. One of these esters features a symmetrical branched C17 tail, while the other is an asymmetric C11 tail.
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![23:2 Diyne PE [DC(8,9)PE]](http://file.medchemexpress.eu/product_pic/hy-w800784.gif)
