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protein-RNA interaction

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108473
    CU-CPT 4a
    1 Publications Verification

    TLR3-IN-1

    Toll-like Receptor (TLR) Cancer
    CU-CPT 4a (TLR3-IN-1) is a potent, highly selective TLR3 signaling inhibitor. CU-CPT 4a represses the expression of downstream signaling pathways mediated by the TLR3/dsRNA complex, including TNF-α and IL-1β .
    CU-CPT 4a
  • HY-161402

    DNA Methyltransferase Cancer
    METTL16-IN-1 (Compound 45) is a potent METTL16 inhibitor with an IC50 value of 1.7 μM and a Kd value of 1.35 μM .
    METTL16-IN-1
  • HY-155237

    Others Cancer
    LIN28-IN-1 (compound 5) is an inhibitor of the RNA-binding and regulatory protein LIN28 and binds to the LIN28 cold shock domain (CSD). LIN28-IN-1 effectively inhibits the interaction between LIN28 and let-7 miRNA (IC50: 5.4 μM), blocking the negative impact of LIN28 on epigenetic gene regulation. LIN28-IN-1 significantly inhibits the proliferation of JAR cancer cells expressing LIN28 (IC50: 6.4 μM) .
    LIN28-IN-1

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