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Results for "

synthetic

" in MedChemExpress (MCE) Product Catalog:

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By Research Areas:	Cancer (290) Cardiovascular Disease (66) Endocrinology (131) Infection (172) Inflammation/Immunology (163) Metabolic Disease (82) Neurological Disease (94)
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Oligonucleotides:	Nucleosides and their Analogs (2) Decoy ODNs (1) Thickeners (1) Phospholipids (3) Antisense Oligonucleotides (6) siRNAs (2) Nucleotides and their Analogs (3) Pegylated Lipids (2) CpG ODNs (6) Emulsifiers (1) Cationic Lipids (4) Polymers (2) Sweetening Agents (1)

945

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

194

Peptides

Inhibitory Antibodies

Natural
Products

104

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1662

Hexestrol 2 Publications Verification	Estrogen Receptor/ERR	Endocrinology
Hexestrol is a nonsteroidal synthetic estrogen, with a K_i of 0.06 and 0.06 nM for estrogen receptor alpha (ERα) and ERβ. Hexestrol can be used for the research of the diseases caused by estrogen deficiencym, and it also can increase the weight of cattle .

HY-B0487

Ethisterone Pregneninolone; 17α-Ethynyltestosterone	Estrogen Receptor/ERR	Endocrinology
Ethisterone (Pregneninolone), a synthetic steroidal estrogen, is an orally active steroidal contraceptive agent. Ethisterone is reported for androgenic activity, used for the research of the gynecological disorders .

HY-P10462

SAP15 synthetic anti-inflammatory peptide 15	HDAC NF-κB	Inflammation/Immunology
SAP15 (Synthetic anti-inflammatory peptide 15) is a synthetic anti-inflammatory peptide consisting of 15 amino acids designed from human beta-defensin 3. SAP15 has the ability to penetrate cells and is able to induce downregulation of intracellular inflammation. SAP15 inhibits inflammation by inhibiting the phosphorylation of HDAC5 and thereby reducing the phosphorylation of NF-κB p65. In LPS-induced macrophages, SAP15 inhibits HDAC5 and NF-κB p65 phosphorylation. In addition, SAP15 treatment increased the expression of aggrecan and type II collagen and decreased the expression of osteocalcin in LPS-induced chondrocytes. SAP15 can be used in the study of inflammation regulation and anti-inflammatory therapy of biomaterials .

HY-166863

*L-erythro-Sphingosine(synthetic)*	Biochemical Assay Reagents	Others
L-erythro-Sphingosine(synthetic) is a biochemical assay reagent.

HY-P1459

*Sphistin Synthetic* Peptide(12-38,Fitc in N-Terminal-Fluorescently Labeled Peptide)**	Bacterial	Infection
Sphistin Synthetic Peptide (12-38, Fitc in N-Terminal-Fluorescently Labeled Peptide) is a truncated fragments of Sphistin Synthetic Peptide that shows potent antimicrobial activity.

HY-164652

m-BBIG dihydrochloride	Biochemical Assay Reagents	Others
m-BBIG dihydrochloride is a member of Bis-iminoguanidine (BIG) family and can be utilized in synthetic chemistry .

HY-114582

Lexitropsin	Others	Others
Lexitropsin is a netropsin derivative which is determined the binding and specificity properties in interaction with DNA and synthetic polynucleotides .

HY-P10082

Ac-VETD-AMC	Caspase	Others
Ac-VETD-AMC is a synthetic peptide substrate for caspase 8. Ac-VETD-AMC also has potential to assess functional activity of recombinant phytaspase .

HY-161752

Antibacterial agent 224	Bacterial	Infection
Antibacterial agent 224 is a potent and selective synthetic hydrazone inhibitor against the Salmonella PhoP/PhoQ system .

HY-129801

N-Ethyl Hexylone hydrochloride	Others	Others
N-Ethyl Hexylone hydrochloride is a synthetic Cathinone and analogue of methylone and other beta-keto methylenedioxyamphetamines .

HY-106365

Rofleponide	Others	Endocrinology
Rofleponide is a synthetic glucocorticoid that has a high affinity for rat thymic glucocorticoid receptors and has high anti-inflammatory efficacy in experimental animal models .

HY-122245

Sortin2	Others	Cancer
Sortin2 is a synthetic compound. Sortin2 can affect protein targeting to the vacuole in Saccharomyces cerevisiae .

HY-B1662R

Hexestrol (Standard)	Estrogen Receptor/ERR	Endocrinology
Hexestrol (Standard) is the analytical standard of Hexestrol. This product is intended for research and analytical applications. Hexestrol is a nonsteroidal synthetic estrogen, with a Ki of 0.06 and 0.06 nM for estrogen receptor alpha (ERα) and ERβ. Hexestrol can be used for the research of the diseases caused by estrogen deficiencym, and it also can increase the weight of cattle .

HY-117444

ONO-9780307	LPL Receptor	Cancer
ONO-9780307 is a specific synthetic LPA1 (lysophosphatidic acid receptor 1) antagonist with an IC₅₀ value of 2.7 nM .

HY-D1373

HBC HBC 530	DNA Stain	Cancer
HBC is a green fluorescent protein (GFP) fluorophore-like synthetic dye, with a structurally rigid electron acceptor and a strong electron donor. HBC is used to detect RNA localization .

HY-W351340

4-(Benzyloxy)-2-nitrophenol	Fluorescent Dye	Others
4-(Benzyloxy)-2-nitrophenol is a synthetic building block that can be used in the synthesis of fluorescent ion indicators .

HY-17578

Pneumocandin B0 L-688786	Fungal Antibiotic	Infection
Pneumocandin B0 (L-688786), the precursor of the antifungal agent Caspofungin acetate, is an antifungal agent belonging to the echinocandin family. Pneumocandin B0, derived from the flamentous fungus Glarea lozoyensis, is a synthetic intermediate of Cancidas .

HY-P1701

Morphiceptin	Opioid Receptor	Cardiovascular Disease Neurological Disease
Morphiceptin is a potent and specific agonist for morphine (μ) receptors. Morphiceptin, as a synthetic peptide, is the amide of a fragment of the milk protein β-casein. Morphiceptin has morphinelike activities and is highly specific for morphine (μ) receptors but not for enkephalin (⸹) receptors .

HY-N8495

4'-Hydroxyflavanone	Others	Metabolic Disease
4'-Hydroxyflavanone is an inhibitor of SREBP maturation and lipid synthesis. 4'-Hydroxyflavanone is a synthetic analogue of flavanone, has potential for hepatic steatosis and dyslipidemia research .

HY-W250152

Polycytidylic acid potassium	Biochemical Assay Reagents	Inflammation/Immunology
Polycytidylic acid potassium is an immunostimulant and synthetic double-stranded RNA. Polycytidylic acid potassium can be used experimentally to model viral infections in vivo. Polycytidylic acid potassium is a common tool in immune system research .

HY-112205

RR-11a	Legumain	Cancer
RR-11a is a synthetic enzyme inhibitor of Legumain (IC₅₀=31-55 nM). RR-11a can be used for the research of cancer and acute myocardial infarction (AMI) .

HY-167545

1-Palmitoyl-2-oleoylphosphatidylethanolamine POPE	Liposome Biochemical Assay Reagents	Others
1-Palmitoyl-2-oleoylphosphatidylethanolamine (POPE) is a PE-based synthetic phospholipid that can intercalate with other amphiphilic molecules to form stable bilayers at physiological pH. 1-Palmitoyl-2-oleoylphosphatidylethanolamine can be used in drug delivery research .

HY-109127A

Berotralstat dihydrochloride 1 Publications Verification BCX7353 dihydrochloride	Kallikrein	Others
Berotralstat dihydrochloride is a low toxicity, effective, highly specific, second-generation, synthetic and orally active plasma kallikrein inhibitor used for the research of hereditary angioedema (HAE) attacks. Berotralstat dihydrochloride works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE .

HY-N4115

Syrosingopine 4 Publications Verification Su 3118	Monocarboxylate Transporter	Cardiovascular Disease Cancer
Syrosingopine (Su 3118) is an orally active lactate transporters (MCT1/MCT4) dual inhibitor, which can reduce glycolysis and induce synthetic lethality in cancer cells when combine with metformin. Syrosingopine shows anti-hypertensive activity by depleting peripheral stores of norepinephrine .

HY-P5309

(Thr(GalNAc)4,7,15,Ser(GalNAc)9,11)-IgA1 Hinge Region Peptide	Biochemical Assay Reagents	Inflammation/Immunology
(Thr(GalNAc)4,7,15,Ser(GalNAc)9,11)-IgA1 Hinge Region Peptide is a synthetic glycopeptide and can be used for detection of gender difference and epitope specificity of IgG antibody activity against IgA1 hinge portion in IgA nephropathy patients .

HY-109127R

Berotralstat (Standard)	Ser/Thr Protease	Others
Berotralstat (Standard) is the analytical standard of Berotralstat. This product is intended for research and analytical applications. Berotralstat (BCX7353) is a low toxicity, effective, highly specific, second-generation, synthetic and orally active plasma kallikrein inhibitor used for the research of hereditary angioedema (HAE) attacks. Berotralstat works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE .

HY-145860

PHGDH-IN-2	Phosphoglycerate Dehydrogenase (PHGDH)	Cancer
PHGDH-IN-2 is a potent and NAD ⁺ competitive PHGDH inhibitor with an IC₅₀ of 5.2 µM. PHGDH-IN-2 inhibits the serine synthetic pathway in MDA-MB-468 cells. PHGDH-IN-2 inhibits the growth of PHGDH-dependent cancer cells .

HY-151661

N3-L-Val-OH (CHA) L-azidovaline (CHA)	ADC Linker	Others
N3-L-Val-OH (CHA) is a click chemistry containing an azide group, a valine derivative. N3-L-Val-OH (CHA) can also be used as a synthetic intermediate for Valaciclovir (Valacyclovir) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-B1278B

(±)-α-Tocopherol acetate (±)-Vitamin E acetate	Biochemical Assay Reagents	Infection
(±)-α-Tocopherol acetate ((±)-Vitamin E acetate), is a orally active synthetic form of vitamin E. (±)-α-Tocopherol acetate is the ester of acetic acid and α-tocopherol. (±)-α-Tocopherol acetate can be used for the research of the susceptibility of farmed fish to infectious diseases .

HY-145268

SLEC-11	Others	Cancer
SLEC-11 acts as a potential synthetic lethal lead for the research of gastric cancer. AL-GDa62 shows EC₅₀ of 12.2 μM and 8.2 μM for isogenic mammary epithelial cells MCF10A-WT (wild-type) and MCF10A-CDH1 ^-/- .

HY-145269

AL-GDa62	Others	Cancer
AL-GDa62 acts as a potential synthetic lethal lead for the research of gastric cancer. AL-GDa62 shows EC₅₀ of 3.2 μM and 2 μM for isogenic mammary epithelial cells MCF10A-WT (wild-type) and MCF10A-CDH1 ^-/- .

HY-114671

Taprostene CG-4203	Prostaglandin Receptor	Cardiovascular Disease
Taprostene (CG-4203) is a synthetic, chemically stable analogue of Prostacyclin (PGI2). Taprostene exhibits endothelium and myocardial protecting actions after acute myocardial ischemia and reperfusion in cats. Taprostene enhances cytoprotective actions, while minimizing unwanted hemodynamic effects .

HY-134581A

Enpatoran hydrochloride 5 Publications Verification M5049 hydrochloride	Toll-like Receptor (TLR)	Inflammation/Immunology
Enpatoran (M5049) hydrochloride is a potent, orally active and dual TLR7/8 inhibitor with IC₅₀s of 11.1 nM and 24.1 nM in HEK293 cells, respectively. Enpatoran hydrochloride is inactive against TLR3, TLR4 and TLR9. Enpatoran hydrochloride can block molecule synthetic ligands and natural endogenous RNA ligands. Enpatoran hydrochloride exhibits excellent pharmacokinetic properties in vivo. Enpatoran hydrochloride can be used for both innate and adaptive autoimmunity blocking research .

HY-B1278BR

(±)-α-Tocopherol acetate (Standard)	Biochemical Assay Reagents	Infection
(±)-α-Tocopherol acetate (Standard) is the analytical standard of (±)-α-Tocopherol acetate. This product is intended for research and analytical applications. (±)-α-Tocopherol acetate ((±)-Vitamin E acetate), is a orally active synthetic form of vitamin E. (±)-α-Tocopherol acetate is the ester of acetic acid and α-tocopherol. (±)-α-Tocopherol acetate can be used for the research of the susceptibility of farmed fish to infectious diseases .

HY-131701

Lactosyl-C18-sphingosine C18 Lactosyl(β) Ceramide; Lactosyl Sphingosine; Lyso-Lactosylceramide (synthetic)	Endogenous Metabolite	Metabolic Disease
Lactosyl-C18-sphingosine (C18 Lactosyl(β) Ceramide; Lactosyl Sphingosine) is a bioactive sphingolipid that is a form of lactosylceramide but lacks the fatty acyl group. Lysolactosylceramide (1-50 μM) reduces the viability of human neutrophils in a concentration-dependent manner. Unlike lactosylceramide, Lactosyl-C18-sphingosine has no effect on protein synthesis and cell proliferation in cardiomyocytes. Lactosyl-C18-sphingosine is a lysoganglioside GM3.

HY-119506

KL044 1 Publications Verification	Cryptochrome	Metabolic Disease
KL044, a stabilizer of the clock protein cryptochrome (CRY) , is a potent chemical probe with a pEC₅₀ value of 7.32, leading to the extension of the circadian period and repression of Per2 activity .

HY-P1626

Acetyl tetrapeptide-15	Opioid Receptor	Neurological Disease
Acetyl tetrapeptide-15 is a synthetic peptide used in the cosmetics for sensitive skin. Acetyl tetrapeptide-15 is derived from endomorphin-2 (Tyr-Pro-Phe-Phe-NH2), a human μ-opioid agonist with selective anti-nociceptive effect. Acetyl tetrapeptide-15 reduces skin hyperreactivity producing inflammatory, chronic and neuropathic pain, by increasing the threshold of neuronal excitability in μ-opioid receptor via an endorphin-like pathway .

HY-B1182

Chromocarb Chromone-2-carboxylic acid	Others	Cardiovascular Disease
Chromocarb is a synthetic vasoprotectant.

HY-17405

Alarelin Acetate 1 Publications Verification Alarelin	GnRH Receptor	Endocrinology
Alarelin acetate is a synthetic GnRH agonist.

HY-100268

Xenalamine Xenazoic acid; CV58903	Antibiotic	Infection
Xenalamine is a synthetic antiviral agent.

HY-P3375

Mazdutide IBI-362; LY-3305677; OXM-3	GCGR GLP Receptor	Metabolic Disease
Mazdutide (IBI-362; LY-3305677) is a long-acting synthetic oxyntomodulin analog. Mazdutide is also a co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR). Mazdutide binds human and mouse GCGR (K_i: 17.7 nM and 15.9 nM, respectively) and GLP-1R (K_i: 28.6 nM and 25.1 nM, respectively) and stimulates insulin secretion from mouse islets (EC₅₀: 5.2 nM). Mazdutide is used in studies of obesity and type 2 diabetes (T2D) .

HY-101829

Sulfaproxiline Sulfaproxylin; Sulfaproxyline	Bacterial	Infection
Sulfaproxiline is a synthetic antimicrobial agent that is sulfonamide.

HY-P3375A

Mazdutide TFA IBI-362 TFA; LY-3305677 TFA; OXM-3 TFA	GCGR GLP Receptor	Metabolic Disease
Mazdutide (IBI-362; LY-3305677) TFA is a long-acting synthetic oxyntomodulin analog. Mazdutide is also a co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR). Mazdutide TFA binds human and mouse GCGR (K_i: 17.7 nM and 15.9 nM, respectively) and GLP-1R (K_i: 28.6 nM and 25.1 nM, respectively) and stimulates insulin secretion from mouse islets (EC₅₀: 5.2 nM). Mazdutide TFA is used in studies of obesity and type 2 diabetes (T2D) .

HY-101575

Acetylazide Acetylkelfizina; Acetylsulfamethoxypyrazine; FI6073	Bacterial Antibiotic	Infection
Acetylazide is a synthetic broad-spectrum bacteriostatic antibiotic.

HY-B0896

Triacetin Glyceryl triacetate; 1,2,3-Triacetoxypropane	Fungal Endogenous Metabolite	Others
Triacetin is a synthetic compound that is a triester of glycerol and acetic acid.

HY-B0989

Carzenide 4-Sulfamoylbenzoic acid	Others	Others
Carzenide is an organic synthesis intermediate, for synthetic drug.

HY-B1203

Fludrocortisone 9α-Fludrocortisone; 9α-Fluorcortisol	Mineralocorticoid Receptor	Inflammation/Immunology
Fludrocortisone, a synthetic mineralocorticoid with anti-inflammatory activity.

HY-U00089

Hydrocortisone cypionate	Glucocorticoid Receptor	Inflammation/Immunology Endocrinology
Hydrocortisone cypionate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester.

HY-101703

Ro 31-9790 1 Publications Verification GI4747	MMP	Inflammation/Immunology
Ro 31-9790 is a synthetic metalloproteinase (MMP) inhibitor.

HY-B1072

Phenothrin	Parasite	Infection
Phenothrin is a synthetic pyrethroid that kills adult fleas and ticks.

Cat. No.	Product Name

HY-L0105V

*InterBioScreen Synthetic* Compounds Library**	485,000 compounds
InterBioScreen Synthetic Compounds Library contains about 485,000 immediately available compounds. The library is generated by very rigorously selecting the most interesting classes of compounds that are most likely to become new drugs or plant protection agents or veterinary preparations.

HY-L0114V

Pharmeks Screening Compound Library	439,804 compounds
This library contains about 439,804 natural and synthetic screening compounds. The information in the database includes logP, H-bond donors, H-bond acceptors, rotable bonds.

HY-L0120V

Asinex BioDesign Library

170,269 compounds

“BioDesign” approach incorporates key structural features of known pharmacologically relevant natural products (e.g. alkaloids and other secondary metabolites) into synthetically feasible medicinal chemistry scaffolds. In order to identify the privileged pharmacophores, ring systems and linkers, we have carried out statistical analysis of structural features of natural products, marketed drugs, and drug candidates.

Saturated, fused ring, spiro, and bridged systems with a tendency towards multiple chiral centers are highly privileged among natural products and marketed drugs yet these structures are very poorly represented in commercial libraries. This library addressed this market need by incorporating these privileged elements into the design of novel synthetic molecules with high molecular framework diversity, multiple stereogenic centers (≥2), and degree of saturation (Fsp3 > 0.5).

HY-L912V

MegaUni 10M Virtual Diversity Library

10,000,000 compounds

With MCE's 40,662 BBs, covering around 273 reaction types, more than 40 million molecules were generated. Compounds which comply with Ro5 criteria were selected. Inappropriate chemical structures, such as PAINS motifs and synthetically difficult accessible, were removed. Based on Morgan Fingerprint, molecular clustering analysis was carried out, and molecules close to each clustering center were extracted to form this drug-like and synthesizable diversity library. These selected molecules have 805,822 unique Bemis-Murcko Scaffolds (BMS) with diversified chemical space. This library is highly recommended for AI-based lead discovery, ultra-large virtual screening and novel lead discovery.

HY-L910V

MegaUni 50K Virtual Diversity Library

50,000 compounds

MegaUni 50K Virtual Diversity Library consists of 50,000 novel, synthetically accessible, lead-like compounds. With MCE's 40,662 Building Blocks, covering around 273 reaction types, more than 40 million molecules were generated. Based on Morgan Fingerprint and Tanimoto Coefficient, molecular clustering analysis was carried out, and molecules closest to each clustering center were extracted to form a drug-like and synthesizable diversity library. The selected 50,000 drug-like molecules have 46,744 unique Bemis-Murcko Scaffolds (BMS), each containing only 1-3 compounds. This diverse library is highly recommended for virtual screening and novel lead discovery.

HY-L0096V

Vitas-M Screening Compounds Library	1,400,000 compounds
Vitas-M Screening Compounds Library (stock) contains about 1,400,000 chemical substances. They are synthetic small molecule organic compounds for biological screening and lead optimization. Select any number of items as a "cherry pick".

HY-L0087V

Life Chemicals HTS Compound Collection	503,810 compounds
Life Chemicals Collection of small organic molecules for high-throughput screening currently contains 503,810 off-the-shelf products. The Collection is being permanently replenished with de novo designed products having optimal physicochemical parameters for drug discovery.

HY-L0107V

Life Chemicals Natural Product-like Compound Library

13,236 compounds

Natural products are small molecules produced naturally by any organism including primary and secondary metabolites. Nowadays, new drugs based on Natural products are successfully applied to treat tumors, viral and bacterial diseases, and nervous disorders. In response to the current drug discovery demand, we created this natural product-like compound library with 13,236 in-stock synthetic compounds similar to natural ones. The library was designed by 2D fingerprint similarity filtering, chemical descriptor-based and natural-likeness scoring selection. These compounds are useful tools for high throughput screening (HTS) and high content screening (HCS) programs.

HY-L057

Phenols Library

1,207 compounds

Phenolic compounds are usually referred to as a diverse group of naturally occurring compounds with multiple medical properties, such as antioxidants, antimicrobial properties. Those compounds are commonly found in food and plants. They have high synthetic, medicinal and industrial values. Polyphenols are compounds with multiple phenolic functionalities. Naturally occurring polyphenols are known to have biological activities for use as drugs, for example, in diseases like AIDS, heart ailments, ulcer formation, bacterial infection, mutagenesis and neural disorders.

MCE offers a unique collection of 1,207 natural phenol compounds which is a useful tool for drug discovery as an important source of lead compounds.

HY-L0115V

Asinex Macrocycles Library

10,091 compounds

ASINEX has elaborated a library of diverse macrocycles using an effective tool box of synthetic methods. The resulting scaffolds are novel, tremendously diverse, medchem-relevant, macrocyclic frameworks.

Macrocyles tend to be larger than traditional screening molecules which make them perfect discovery tools for targets with shallow or extended binding sites. At the same time, their unique character based on restricted flexibility and ability to form intra-molecular hydrogen bonds allows for design approaches effectively optimizing properties such asaqueous solubility and membrane permeability. Many of these macrocycles have been tested for aqueous and DMSO solubility with cut-offs applied at 10 mM in DMSO and 50 µM in PBS (pH 7.4) followed by PAMPA permeability assay.

HY-L071

Alkaloids Library

553 compounds

Alkaloids are a large and complex group of cyclic compounds that contain N. About 2,000 different alkaloids have been isolated. Important alkaloids include morphine, strychnine, atropine, colchicine, ephedrine, quinine, and nicotine. Alkaloids are useful as diet ingredients, supplements, and pharmaceuticals, in medicine and in other applications in human life. They showed anti-inflammatory, anticancer, analgesics, local anesthetic and pain relief, neuropharmacologic, antimicrobial, antifungal, and many other activities. Alkaloids are also important compounds in organic synthesis for searching new semisynthetic and synthetic compounds with possibly better biological activity than parent compounds.

MCE designs a unique collection of 553 alkaloids that all come from natural products. MCE Alkaloids Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).

HY-L044

Nucleotide Compound Library

544 compounds

Nucleoside and nucleotide analogues are synthetic, chemically modified compounds that have been developed to mimic their physiological counterparts in order to exploit cellular metabolism and subsequently be incorporated into DNA and RNA to inhibit cellular division and viral replication. In addition to their incorporation into nucleic acids, nucleoside and nucleotide analogues can interact with and inhibit essential enzymes such as human and viral polymerases (that is, DNA-dependent DNA polymerases, RNA-dependent DNA polymerases or RNA-dependent RNA polymerases), kinases, ribonucleotide reductase, DNA methyltransferases, purine and pyrimidine nucleoside phosphorylase and thymidylate synthase. These actions of nucleoside and nucleotide analogues have potential therapeutic benefits — for example, in the inhibition of cancer cell growth, the inhibition of viral replication as well as other indications.

MCE offers a unique collection of 544 nucleotide compounds including nucleotide, nucleoside and their structural analogues. MCE Nucleotide Compound Library is a useful tool to discover anti-cancer and antiviral drugs for high throughput screening (HTS) and high content screening (HCS).

Cat. No.	Product Name	Type

HY-D1373

HBC HBC 530	Fluorescent Dyes/Probes
HBC is a green fluorescent protein (GFP) fluorophore-like synthetic dye, with a structurally rigid electron acceptor and a strong electron donor. HBC is used to detect RNA localization .

HY-113823

Naphthol AS-G	Fluorescent Dyes/Probes
Naphthol AS-G is an active compound. Naphthol ASG can be used for a series of synthetic organic pigments (SOP’s) research .

HY-W351340

4-(Benzyloxy)-2-nitrophenol	Fluorescent Dyes/Probes
4-(Benzyloxy)-2-nitrophenol is a synthetic building block that can be used in the synthesis of fluorescent ion indicators .

HY-D0411

Xylene Fast Yellow 2G Acidyellow 17; Yellow 2G	Dyes
Xylene Fast Yellow 2G is a synthetic dye belonging to the class of azo dyes. It is commonly used in the textile industry to dye natural and synthetic fibers as well as in the paper and ink industries. Xylene Fast Yellow 2G produces a bright yellow color that is fade and wash resistant and can be applied to textiles by a variety of methods including dipping, padding and printing.

HY-D1233

Pigment red 202 Quinaridone magenta 202	Dyes
Pigment Red 202 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D1139

Pigment red 177	Dyes
Pigment Red 177 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D1215

Pigment Red 31	Dyes
Pigment Red 31 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D1201

Pigment Red 245	Dyes
Pigment Red 245 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D1155

Pigment red 176	Dyes
Pigment Red 176 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D1064

Pigment red 57	Dyes
Pigment red 57 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0697

Pigment red 95	Dyes
Pigment red 95 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0632

Pigment Red 147	Dyes
Pigment Red 147 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0596

Pigment Red 188	Dyes
Pigment Red 188 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0568

Pigment red 242	Dyes
Pigment Red 242 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0566

Pigment red 185	Dyes
Pigment Red 185 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0549

Pigment red 266	Dyes
Pigment Red 266 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0384

Pigment Red 144	Dyes
Pigment Red 144 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0383

Pigment Red 146	Dyes
Pigment Red 146 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0363

Pigment Red 166	Dyes
Pigment Red 166 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0345

Pigment Red 178	Dyes
Pigment Red 178 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0337

Pigment Red 4	Dyes
Pigment Red 4 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0278

Pigment red 170	Dyes
Pigment Red 170 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D1164

Pigment red 63:1 D&C Red No. 34	Dyes
Pigment red 63:1 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0280

Pigment red 57-1	Dyes
Pigment red 57-1 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-18341F1

Biotin-hexanamide-(L-Thyroxine)	Dyes
Biotin-hexanamide-(L-Thyroxine) is biotinylated L-Thyroxine (HY-18341). L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism .

HY-D0915

Brilliant Blue FCF 2 Publications Verification Acid Blue 9; FD&C Blue No. 1; E133	Dyes
Brilliant Blue FCF is an aromatic hydrocarbon, a synthetic dye produced from petroleum and used as a colorant for food and other substances. The solution has a maximum absorption at 628 nm.

HY-W010991

N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly FAPGG	Chromogenic Substrates Amino acids and Derivatives
N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly (FAPGG) is a synthetic cromogenic substrate for angiotensin converting enzyme (ACE) determination .

HY-D0257

Tartrazine 1 Publications Verification Acid Yellow 23; FD&C Yellow No. 5	Dyes
Tartrazine is an azo acid dye, orange-yellow powder, soluble in water and turns yellow. It is mainly used as a synthetic lemon yellow azo dye for food coloring. It is the most stable colorant.

HY-D0307A

Amaranth Acid Red 27; Azorubin S; FD & C Red Dye No. 2	Dyes
Amaranth is a dark red to purple azo dye used as a food dye and cosmetics. Amaranth is an anionic dye that can be applied to natural and synthetic fibers, leather, paper, and phenol-formaldehyde resins.

HY-147170

(1,1'-Dipyrenyl)dimethyl ether	Fluorescent Dyes/Probes
(1,1'-Dipyrenyl)dimethyl ether exhibits intramolecular excimer fluorescence in competition with fluorescence from the locally excited pyrene chromophore. (1,1'-Dipyrenyl)dimethyl ether is soluble in synthetic phospholipid membranes .

HY-D0193

Ponceau 4R 1 Publications Verification Acid Red 18; New Coccine	Dyes
Ponceau 4R is a synthetic colorant that can be used for food coloring. Ponceau 4R is a strawberry red azo dye that can be used in a variety of foods, usually synthesized from aromatic hydrocarbons, and is stable to light, heat, and acids .

HY-18341F

Biotin-(L-Thyroxine)	Dyes
Biotin-(L-Thyroxine) is the biotinylated L-Thyroxine (HY-18341). L-Thyroxine is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from Biotin-(L-Thyroxine) (T4) .

HY-D1190

DC271	Fluorescent Dyes/Probes
DC271 is a RAR agonist that can be considered a retinoid, eliciting cellular responses consistent with the endogenous retinoid ATRA and the synthetic retinoid EC23. DC271 binds to retinoid protein machinery, including CRABPII, to translocate the endogenous retinoid ATRA into the nucleus .

HY-D0257R

Tartrazine (Standard)	Dyes
Tartrazine (Standard) is the analytical standard of Tartrazine. This product is intended for research and analytical applications. Tartrazine is an azo acid dye, orange-yellow powder, soluble in water and turns yellow. It is mainly used as a synthetic lemon yellow azo dye for food coloring. It is the most stable colorant.

HY-D0307AR

Amaranth (Standard)	Dyes
Amaranth (Standard) is the analytical standard of Amaranth. This product is intended for research and analytical applications. Amaranth is a dark red to purple azo dye used as a food dye and cosmetics. Amaranth is an anionic dye that can be applied to natural and synthetic fibers, leather, paper, and phenol-formaldehyde resins.

HY-D0915R

Brilliant Blue FCF (Standard)	Dyes
Brilliant Blue FCF (Standard) is the analytical standard of Brilliant Blue FCF. This product is intended for research and analytical applications. Brilliant Blue FCF is an aromatic hydrocarbon, a synthetic dye produced from petroleum and used as a colorant for food and other substances. The solution has a maximum absorption at 628 nm.

HY-B1273

Fenipentol 1-Phenyl-1-pentanol	Dyes
Fenipentol (1-Phenyl-1-pentanol), a synthetic derivative of an ingredient of Curcuma longa that is used as a condiment and dye. Fenipentol is also an orally active choleretic agent that plays an important role in release of secretin, gastrin, and pancreatic secretion of bicarbonate and protein .

HY-D0303A

Chrysoidine G Solvent Orange 3 hydrochloride	Dyes
Chrysoidine G (Solvent Orange 3 hydrochloride) is an industrial azoic dye (cationic dye). Chrysoidine G (Solvent Orange 3 hydrochloride) is used for the construction of most textile dyestuffs and also in synthetic industrial compounds. Chrysoidine G (Solvent Orange 3 hydrochloride) concentration can be determined by UV-Vis spectroscopy .

HY-D0312

Mordant Blue 13 Sunchromine Fast Blue MB	Dyes
Mordant Blue 13 is a synthetic dye used in the textile industry. It belongs to a class of metal complex dyes that are able to form strong bonds with fabrics and other materials. Mordant Blue 13 is commonly used for dyeing cotton, wool and silk fibres, it produces a fast blue color. It can be applied to textiles by a variety of methods including impregnation, padding and printing.

HY-D0352

Permanent Orange

Pigment Orange 5

Dyes

Permanent Orange is a synthetic pigment commonly used in the manufacture of paints and coatings. It belongs to the class of organic pigments and consists of carbon and other elements. Permanent Orange produces a bright orange color that is fade and weather resistant, making it ideal for outdoor applications. It can be mixed with other pigments to produce a range of colors and is compatible with a wide range of binders and solvents.

HY-W206911

Erythrosin B sodium salt

Dyes

Erythrosin B sodium salt, is a synthetic azo dye commonly used as a food colorant and textile dye. It is a water-soluble compound that produces a bright red color and is often used to improve the appearance of products. Erythrosin B sodium salt is also used in the textile industry for dyeing wool, silk and leather. However, it has been linked to potentially negative health effects, such as allergic reactions and hyperactivity in children.

HY-D0193A

Ponceau 4R (85%) Acid Red 18 (85%); New Coccine (85%)	Dyes
Ponceau 4R (85%)(Acid Red 18 (85%); New Coccine (85%))is a synthetic colourant that may be used as a food colouring. Ponceau 4R (85%)is a strawberry red azo dye which can be used in a variety of food products, and is usually synthesized fromaromatic hydrocarbons; it is stable to light, heat, and acid but fades in the presence of ascorbic acid .

HY-D1547

1-(3',6'-Bis(ethylamino)-2',7'-dimethyl-3-oxospiro[isoindoline-1,9'-xanthen]-2-yl)-3-phenylurea	Fluorescent Dyes/Probes
1-(3',6'-Bis(ethylamino)-2',7'-dimethyl-3-oxospiro[isoindoline-1,9'-xanthen]-2-yl)-3-phenylurea (compound 1a) can be used as a fast-responsive fluorescent gold ion probe for detection of gold ions in water and synthetic products .

HY-D0214

Rose Bengal sodium 1 Publications Verification	Fluorescent Dyes/Probes
Rose Bengal sodium, a synthetic fluorescein derivative, and is a crimson-coloured dye with the principal component being 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. Rose Bengal sodium has been widely used as an ophthalmic diagnostic agents, and can detect desiccated or damaged cells on the ocular surface. Rose Bengal sodium exhibits antiviral activities .

HY-D0303AR

Chrysoidine G (Standard)

Dyes

Chrysoidine G (Standard) is the analytical standard of Chrysoidine G. This product is intended for research and analytical applications. Chrysoidine G (Solvent Orange 3 hydrochloride) is an industrial azoic dye (cationic dye). Chrysoidine G (Solvent Orange 3 hydrochloride) is used for the construction of most textile dyestuffs and also in synthetic industrial compounds. Chrysoidine G (Solvent Orange 3 hydrochloride) concentration can be determined by UV-Vis spectroscopy .

HY-12489A

Ponceau S, BS

Acid Red 112, BS

Dyes

Both Ponceau S and Ponceau BS are synthetic dyes commonly used in biological research. They are commonly used as protein stains to visualize proteins in western blots and other protein detection analyses. Ponceau S is a red dye, while Ponceau BS is a blue shade of the same dye. Both dyes bind to positively charged amino acid residues in proteins for easy visualization. However, Ponceau S is more commonly used due to its higher sensitivity.

HY-B0450AG

Ciclopirox olamine (GMP)

Ciclopirox ethanolamine (GMP); HOE 296 (GMP)

Fluorescent Dye

Ciclopirox (olamine) (GMP) is Ciclopirox olamine (HY-B0450A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic .

HY-D0352R

Permanent Orange (Standard)

Dyes

Permanent Orange (Standard) is the analytical standard of Permanent Orange. This product is intended for research and analytical applications. Permanent Orange is a synthetic pigment commonly used in the manufacture of paints and coatings. It belongs to the class of organic pigments and consists of carbon and other elements. Permanent Orange produces a bright orange color that is fade and weather resistant, making it ideal for outdoor applications. It can be mixed with other pigments to produce a range of colors and is compatible with a wide range of binders and solvents.

HY-D0214R

Rose Bengal sodium (Standard)

Fluorescent Dyes/Probes

Rose Bengal (sodium) (Standard) is the analytical standard of Rose Bengal (sodium). This product is intended for research and analytical applications. Rose Bengal sodium, a synthetic fluorescein derivative, and is a crimson-coloured dye with the principal component being 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. Rose Bengal sodium has been widely used as an ophthalmic diagnostic agents, and can detect desiccated or damaged cells on the ocular surface. Rose Bengal sodium exhibits antiviral activities .

HY-D0193AR

Ponceau 4R (85%) (Standard)

Dyes

Ponceau 4R (85%) (Standard) is the analytical standard of Ponceau 4R (85%). This product is intended for research and analytical applications. Ponceau 4R (85%)(Acid Red 18 (85%); New Coccine (85%))is a synthetic colourant that may be used as a food colouring. Ponceau 4R (85%)is a strawberry red azo dye which can be used in a variety of food products, and is usually synthesized fromaromatic hydrocarbons; it is stable to light, heat, and acid but fades in the presence of ascorbic acid .

Cat. No.	Product Name	Target	Research Area

HY-P990049

Becotatug JMT-101	EGFR	Cancer
Becotatug (JMT-101) is an IgG1 antibody targeting EGFR that can also be conjugated to Afatinib (HY-10261) and Osimertinib (HY-15772) as a synthetic ADC .

HY-P99554

Topsalysin PRX-302	Inhibitory Antibodies	Cancer
Topsalysin is a PSA-activated protoxin, a pore-forming protein (synthetic proaerolysin) fusion protein with human prostate-specific antigen. Topsalysin has tumor suppression effect in mice modle .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-17578

Pneumocandin B0 L-688786	Infection Alkaloids Human Gut Microbiota Metabolites Microorganisms Pyrrole Alkaloids Source classification Endogenous metabolite Disease Research Fields	Fungal Antibiotic
Pneumocandin B0 (L-688786), the precursor of the antifungal agent Caspofungin acetate, is an antifungal agent belonging to the echinocandin family. Pneumocandin B0, derived from the flamentous fungus Glarea lozoyensis, is a synthetic intermediate of Cancidas .

HY-N8495

4'-Hydroxyflavanone	Flavonoids Monophenols Microorganisms Classification of Application Fields Flavonones Source classification Phenols Metabolic Disease Disease Research Fields	Others
4'-Hydroxyflavanone is an inhibitor of SREBP maturation and lipid synthesis. 4'-Hydroxyflavanone is a synthetic analogue of flavanone, has potential for hepatic steatosis and dyslipidemia research .

HY-B0896

Triacetin Glyceryl triacetate; 1,2,3-Triacetoxypropane	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Fungal Endogenous Metabolite
Triacetin is a synthetic compound that is a triester of glycerol and acetic acid.

HY-B1383

Dichlorisone acetate	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	Endogenous Metabolite
Dichlorisone acetate is a synthetic glucocorticoid corticosteroid used as an anti-inflammatory agent.

HY-B0469

Medroxyprogesterone acetate 15+ Cited Publications Medroxyprogesterone 17-acetate; Farlutin	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids Cancer	Progesterone Receptor Androgen Receptor Glucocorticoid Receptor Endogenous Metabolite
Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors .

HY-15459

Cabazitaxel 15+ Cited Publications XRP6258; RPR-116258A; taxoid XRP6258	Structural Classification Natural Products Classification of Application Fields Taxaceae Source classification Plants Disease Research Fields Taxus chinensis (Pilger) Rehd. Cancer	Microtubule/Tubulin Autophagy
Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.

HY-N0154

Neohesperidin dihydrochalcone 1 Publications Verification Neohesperidin DC; NHDC	Structural Classification Classification of Application Fields Source classification Plants Dihydrochalcones Sweeteners Food Research Flavonoids other families Phenols Polyphenols Inflammation/Immunology Disease Research Fields	Reactive Oxygen Species
Neohesperidin dihydrochalcone is a synthetic glycoside chalcone, is added to various foods and beverages as a low caloric artificial sweetener.

HY-W014885

Decyl acetate	Structural Classification Natural Products Animals Source classification	Others
Decyl acetate is a synthetic pheromone attracting male false codling moths (Cryptophlebia leucotreta) .

HY-116007

Gaxilose	Structural Classification Microorganisms Source classification Saccharides Monosaccharides	Others
Gaxilose is a synthetic lactose analog that can used as a diagnostic tool to detect hypolactasia .

HY-N9240

Acerogenin G	Source classification Sapindaceae Plants Acer nikoense Maxim.	Others
Acerogenin G is a synthetic diarylheptane. Acerogenin G is first isolated from Acer nikoense .

HY-N0679

Retinyl acetate 2 Publications Verification Retinol acetate; Vitamin A acetate	Terpenoids Source classification Diterpenoids Endogenous metabolite Disease Research Fields Cancer	Others
Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities .

HY-117224

Rhizopterin Formylpteroic acid	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Others
Rhizopterin is a growth factor that can form rhizobactin de novo in synthetic medium lacking folate .

HY-W780803

(Z,E)-9,12-Tetradecadienol	Structural Classification Natural Products Animals Source classification	Others
(Z,E)-9,12-Tetradecadienol is a synthetic enhancer of male Ephestia cautella attraction .

HY-Y0079

D-Phenylalanine	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
D-Phenylalanine is the synthetic dextro isomer of phenylalanine. D-Phenylalanine inhibits biofilm development of Pseudoalteromonas sp. SC2014 .

HY-N7495

all-trans-Anhydro Retinol Anhydrovitamin A	Structural Classification Classification of Application Fields Terpenoids Source classification Metabolic Disease Diterpenoids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
all-trans-Anhydro Retinol (Anhydrovitamin A) is a metabolite of Vitamin A. all-trans-Anhydro Retinol is used in synthetic multivitamin preparations .

HY-B0896R

Triacetin (Standard) Glyceryl triacetate (Standard); 1,2,3-Triacetoxypropane (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite Fungal
Triacetin (Standard) is the analytical standard of Triacetin. This product is intended for research and analytical applications. Triacetin is a synthetic compound that is a triester of glycerol and acetic acid.

HY-114502

Chrysanthemic acid NSC 11779	Structural Classification Tanacetum cinerariifolium (Treviranus) Schultz Bipontinus Ketones, Aldehydes, Acids Source classification Plants Compositae	Others
Chrysanthemic acid (NSC 11779) is an organic compound that is associated with a variety of natural and synthetic insecticides for the prevention of insect-borne diseases, among others .

HY-B1393

Dehydrocholic acid	Microorganisms Source classification	Others
Dehydrocholic acid is a synthetic bile acid produced by the oxidation of bile acids and is used as a bile excretory agent to increase bile production and remove increased bile acid load.

HY-Y0850O

Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed) PVA (Mw 31000-50000, 87-89% hydrolyzed); Poly(Ethenol) (Mw 31000-50000, 87-89% hydrolyzed)	Classification of Application Fields Disease Research Fields Cancer	Biochemical Assay Reagents
Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed) is a synthetic polymer derived from polyvinyl acetate through partial or complete hydroxylation .

HY-113325

NADP 5+ Cited Publications	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes .

HY-W020044

DL-alpha-Tocopherol 3 Publications Verification DL-α-Tocopherol	Structural Classification Duchesnea indica (Andr.) Focke Monophenols Classification of Application Fields Source classification Rosaceae Other Diseases Phenols Plants Disease Research Fields	Ferroptosis
DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB .

HY-N1635

1-Methoxyindole-3-carboxylic acid	Structural Classification Alkaloids Source classification Plants Brassicaceae Isatis indigotica Fortune Indole Alkaloids	Others
1-Methoxyindole-3-carboxylic acid (compound 5) is synthetic from a phytoalexin nucleophilic substitution reaction selectively at the 2-position .

HY-116117

Salicylcurcumin	Structural Classification Monophenols Animals Source classification Phenols	Others
Salicylcurcumin is a synthetic curcumin analogue with antioxidant activity. Salicylcurcumin may affect lipid peroxidation in fish, favoring increased survival, disease resistance, and ultimately growth rate .

HY-120529

Aciculatin	Structural Classification Flavonoids Flavones Gramineae Source classification Plants Themeda arguens (L.) Hack.	Others
Aciculatin is a compound with cytotoxic, anti-inflammatory and anti-arthritic activities, and its synthetic route including specific chemical reaction steps was determined through the first total synthesis.

HY-113325A

NADP sodium hydrate 5+ Cited Publications	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NADP sodium hydrate is the sodium salt hydrate form of NADP (HY-113325). NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes .

HY-B0469R

Medroxyprogesterone acetate (Standard) 15+ Cited Publications Medroxyprogesterone 17-acetate(Standard); Farlutin (Standard)	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids Cancer	Progesterone Receptor Androgen Receptor Glucocorticoid Receptor Endogenous Metabolite
Medroxyprogesterone acetate (Standard) is the analytical standard of Medroxyprogesterone acetate. This product is intended for research and analytical applications. Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors .

HY-W007273

11-Dodecyn-1-ol	Structural Classification Natural Products Animals Source classification	Others
11-Dodecyn-1-ol is a synthetic intermediate of the sex pheromone (Z,E)-11,13,15-Hexadecatrienyl acetate for Thaumetopoea processionea .

HY-B0129

Aztreonam 5+ Cited Publications SQ-26,776	Classification of Application Fields Disease Research Fields Cancer	Penicillin-binding protein (PBP) Bacterial Antibiotic
Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3).

HY-B0260

Methylprednisolone 5+ Cited Publications U 7532	Cardiovascular Disease Classification of Application Fields Disease Research Fields	Glucocorticoid Receptor Autophagy SARS-CoV Bacterial
Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels .

HY-P99554

Topsalysin PRX-302	Classification of Application Fields Disease Research Fields Cancer	Others
Topsalysin is a PSA-activated protoxin, a pore-forming protein (synthetic proaerolysin) fusion protein with human prostate-specific antigen. Topsalysin has tumor suppression effect in mice modle .

HY-15459R

Cabazitaxel (Standard)	Structural Classification Natural Products Taxaceae Source classification Plants Taxus chinensis (Pilger) Rehd.	Microtubule/Tubulin Autophagy
Cabazitaxel (Standard) is the analytical standard of Cabazitaxel. This product is intended for research and analytical applications. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.

HY-N0679R

Retinyl acetate (Standard)	Terpenoids Source classification Diterpenoids Endogenous metabolite	Others
Retinyl acetate (Standard) is the analytical standard of Retinyl acetate. This product is intended for research and analytical applications. Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities .

HY-F0002A

NADP disodium salt 5+ Cited Publications Disodium NADP	Structural Classification Microorganisms other families Animals Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Plants Disease Research Fields	Endogenous Metabolite
NADP disodium salt is the disodium salt form of NADP (HY-113325). NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes .

HY-I0508

Phthalic acid 2 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Biochemical Assay Reagents
Phthalic acid is the final common metabolite of phthalic acid esters (PAEs). Phthalic acid can be used for the synthesis of synthetic agents, such as isophthalic acid (IPA), and terephthalic acid (TPA). Phthalic acid has applications in the preparation of phthalate ester plasticizers .

HY-18341B

L-Thyroxine sodium 5+ Cited Publications Levothyroxine sodium; T4 sodium	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Cancer	Thyroid Hormone Receptor Endogenous Metabolite
L-Thyroxine sodium (Levothyroxine sodium) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

HY-B0147

Pefloxacin 2 Publications Verification Pefloxacinium	Infection Classification of Application Fields Disease Research Fields	Bacterial Antibiotic
Pefloxacin is a an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse) Target: DNA gyrase Pefloxacin is a synthetic chemotherapeutic agent used to treat severe and life-threatening bacterial infections.

HY-N0154R

Neohesperidin dihydrochalcone (Standard)	Structural Classification Flavonoids other families Source classification Phenols Polyphenols Plants Dihydrochalcones	Reactive Oxygen Species
Neohesperidin dihydrochalcone (Standard) is the analytical standard of Neohesperidin dihydrochalcone. This product is intended for research and analytical applications. Neohesperidin dihydrochalcone is a synthetic glycoside chalcone, is added to various foods and beverages as a low caloric artificial sweetener.

HY-18341

L-Thyroxine 5+ Cited Publications Levothyroxine; T4	Structural Classification Classification of Application Fields Source classification Endocrine diseases Endogenous metabolite Monophenols Immune System Disorder Ketones, Aldehydes, Acids Disease markers Phenols Nervous System Disorder Disease Research Fields Endocrinology	Thyroid Hormone Receptor Endogenous Metabolite
L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

HY-N12933

11-Octadecenal	Structural Classification Natural Products Source classification Plants Compositae Launaea resedifolia L	Bacterial
11-Octadecenal is a volatile oil isolated from antibacterial components of coumarin, which can be isolated from synthetic insect sex pheromones used for attracting wax moths (Achroia grisella) .

HY-N12937

(Z)-7-Decenyl acetate	Structural Classification Natural Products Animals Source classification	Others
(Z)-7-Decenyl acetate is a synthetic insect sex pheromone used for attracting turnip moths (Agrotis segetum), which can be isolated from analogs with lower activity than natural pheromones .

HY-18341A

L-Thyroxine sodium salt pentahydrate 5+ Cited Publications Sodium levothyroxine pentahydrate	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Cancer	Thyroid Hormone Receptor Endogenous Metabolite
L-Thyroxine sodium salt pentahydrate (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .

HY-N7142

DL-Norepinephrine hydrochloride 1 Publications Verification	Structural Classification Neurological Disease Classification of Application Fields Source classification Phenols Polyphenols Endogenous metabolite Disease Research Fields Endocrinology	Adrenergic Receptor
DL-Norepinephrine hydrochloride is a synthetic phenylethylamine that mimics the sympathomimetic actions of the endogenous norepinephrine．DL-Norepinephrine hydrochloride is a neurotransmitter targets α1 and β1 adrenoceptors, has an increasing effect on subendocardial oxygen tension .

HY-N10356

4,27-Dimethyl withaferin A	Source classification Withania somnifera Plants Solanaceae Steroids	Others
4,27-Dimethyl withaferin A is a synthetic analog of withanolide natural products. 4,27-Dimethyl withaferin A has the potential for the research of neurodegenerative diseases (extracted from patent WO2015077780A1) .

HY-105088

Pexiganan MSI 78 free base	Infection Structural Classification Natural Products Animals Classification of Application Fields Source classification Disease Research Fields	Bacterial
Pexiganan (MSI 78 free base) is a synthetic analog of magainin 2. Pexiganan is a potent and orally active broad-spectrum antimicrobial peptide. Pexiganan can be used in the research of infections, such as diabetic foot ulcer infections .

HY-N12886

(11Z)-Hexadecen-7-yn-1-yl acetate	Structural Classification Natural Products Animals Source classification	Others
(11Z)-Hexadecen-7-yn-1-yl acetate (7) is a synthetic sex pheromone that shows better bioactivity than sex pheromones isolated from Pectinophora gossypiella Saunders .

HY-N12823

Caprazene	Structural Classification Microorganisms Antibiotics Source classification	Bacterial
Caprazene is an antimycobacterial compound and precursor molecule for semi-synthetic antibacterial antibiotics, used for studies on tuberculosis and Mycobacterium avium complex infections, which can be isolated from the acid-treated caprazamycin (CPZ) A-G mixture .

HY-Y0079R

D-Phenylalanine (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
D-Phenylalanine (Standard) is the analytical standard of D-Phenylalanine. This product is intended for research and analytical applications. D-Phenylalanine is the synthetic dextro isomer of phenylalanine. D-Phenylalanine inhibits biofilm development of Pseudoalteromonas sp. SC2014 .

HY-A0203A

Pentosan Polysulfate Sodium (W/W 43%)	Classification of Application Fields Disease Research Fields Cancer	HIV
Pentosan Polysulfate Sodium is an orally bioavailable, semi-synthetic medication with anti-inflammatory and pro-chondrogenic properties. Pentosan Polysulfate Sodium also is a potent and selective anti-HIV agent. Pentosan Polysulfate Sodium is used for the treatment of interstitial cystitis .

HY-N12883

(E,E)-11,13-Hexadecadien-1-ol	Structural Classification Natural Products Animals Source classification	Others
(E,E)-11,13-Hexadecadien-1-ol is a synthetic isomer of the hexane extract of the unmated female or female pheromone glands that can attract male Amyelois transitella (Walker) (Lepidoptera: Pyralidae) .

HY-18341F

Biotin-(L-Thyroxine)	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology	Thyroid Hormone Receptor Endogenous Metabolite
Biotin-(L-Thyroxine) is the biotinylated L-Thyroxine (HY-18341). L-Thyroxine is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from Biotin-(L-Thyroxine) (T4) .

Cat. No.	Product Name	Chemical Structure

HY-B0332S

Menadione-d3
Menadione-d₃ is the deuterium labeled Menadione. Menadione, a synthetic naphthoquinone, can be converted to active vitamin K2 in vivo.

HY-14664AS

Fluvastatin-d6 sodium
Fluvastatin-d₆ (sodium) is deuterium labeled Fluvastatin sodium. Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM.

HY-14598S

Diethylstilbestrol-d8
Diethylstilbestrol-d₈ is the deuterium labeled Diethylstilbestrol. Diethylstilbestrol, a synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders[1][2].

HY-B1203S

Fludrocortisone-d5
Fludrocortisone-d₅ is the deuterium labeled Fludrocortisone. Fludrocortisone, a synthetic mineralocorticoid with anti-inflammatory activity.

HY-B1203S1

Fludrocortisone-d2
Fludrocortisone-d₂ is the deuterium labeled Fludrocortisone. Fludrocortisone, a synthetic mineralocorticoid with anti-inflammatory activity.

HY-B0111RS

Drospirenone-13C3
Drospirenone- ¹³C₃ is ¹³C labeled Drospirenone. Drospirenone (Dihydrospirorenone) is a synthetic progesterone that is an analog of Spironolactone .

HY-B0111S

Drospirenone-d4
Drospirenone-d₄ is the deuterium labeled Drospirenone. Drospirenone (Dihydrospirorenone) is a synthetic progestin that is an analog to spironolactone[1][2].

HY-B0214S

Prednisone-d8
Prednisone-d₈ is the deuterium labeled Prednisone. Prednisone (Adasone) is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound.

HY-B0648S

Medroxyprogesterone-d3
Medroxyprogesterone-d₃ is the deuterium labeled Medroxyprogesterone. Medroxyprogesterone is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist.

HY-17420S1

Cyclophosphamide-d8
Cyclophosphamide-d₈ is deuterium labeled Cyclophosphamide. Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant.

HY-B0370S

Tolnaftate (D7)
Tolnaftate-d₇ is the deuterium labeled Tolnaftate. Tolnaftate (NP-27) is a synthetic thiocarbamate used as an anti-fungal agent[1][2].

HY-13566AS

Belotecan-d7 hydrochloride
Belotecan-d₇ (hydrochloride) is the deuterium labeled Belotecan hydrochloride. Belotecan hydrochloride (CKD-602 hydrochloride), a Topoisomerase I inhibitor, is a synthetic camptothecin derivative[1][2].

HY-123178S

Fenpropathrin-d5
Fenpropathrin-d₅ is the deuterium labeled Fenpropathrin. Fenpropathrin is a synthetic pyrethroid insecticide in agriculture. Fenpropathrin may induces parkinsonian symptoms progressively[1].

HY-131144S

AMOZ-d5
AMOZ-d₅ is a deuterium labeled AMOZ. AMOZ, a tissue bound metabolite of Furaltadone, Furaltadone is a synthetic nitrofuran antibiotic widely used[1].

HY-15459S1

Cabazitaxel-d9
Cabazitaxel-d₉ is deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.

HY-B0330S

Levofloxacin-d8
Levofloxacin-d₈ is the deuterium labeled Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

HY-17420S

Cyclophosphamide-d4
Cyclophosphamide-d₄ is the deuterium labeled Cyclophosphamide. Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant[1][2].

HY-10394S

Linezolid-d3
Linezolid-d₃ is a deuterium labeled Linezolid (PNU-100766). Linezolid is a synthetic antibiotic that acts by inhibiting the initiation of bacterial protein synthesis[1].

HY-17420AS

Cyclophosphamide-d8 hydrate
Cyclophosphamide-d₈ (hydrate) is the deuterium labeled Cyclophosphamide hydrate. Cyclophosphamide hydrate is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities[1][2].

HY-B0469S

Medroxyprogesterone acetate-d3
Medroxyprogesterone acetate-d₃ is deuterium labeled Medroxyprogesterone acetate. Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors[1].

HY-B0330S1

(S)-Ofloxacin-d3
(S)-Ofloxacin-d₃ is the deuterium labeled Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

HY-A0096S

Iloprost-d4
Iloprost-d₄ (Ciloprost-d4) is the deuterium labeled Iloprost. Iloprost (ZK 36374) is a synthetic analogue of prostacyclin PGI2[1][2].

HY-15459S

Cabazitaxel-d6
Cabazitaxel-d₆ is the deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity[1][2].

HY-13234S

Rifaximin-d6
Rifaximin-d₆ is the deuterium labeled Rifaximin. Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity[1][2].

HY-17396S

Butenafine-13C,d3 hydrochloride
Butenafine- ¹³C,d₃ (hydrochloride) is the ¹³C- and deuterium labeled. Butenafine Hydrochloride (KP363 Hydrochloride) is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase.

HY-17412S

Minocycline-d6 hydrochloride
Minocycline-d₆ hydrochloride is deuterated labeled Minocycline hydrochloride (HY-17412). Minocycline hydrochloride is an orally effective semi-synthetic tetracycline antibiotic and HIF-1α inhibitor .

HY-13666S

Levamisole-d5 hydrochloride
Levamisole-d₅ (hydrochloride) is the deuterium labeled Levamisole hydrochloride. Levamisole ((-)-Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV[1][2].

HY-B0925AS

Oxacillin-d5
Oxacillin-d₅ is the deuterium labeled Oxacillin[1]. Oxacillin is an orally active synthetic penicillin with good bactericidal activity against staphylococci and other gram-positive pathogens[2].

HY-N0679S4

Retinyl acetate-d4
Retinyl acetate-d₄ is the deuterium labeled Retinyl acetate[1]. Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities[2].

HY-Y0079S

D-Phenylalanine-d5
D-Phenylalanine-d₅ is the deuterium labeled D-Phenylalanine. D-Phenylalanine is the synthetic dextro isomer of phenylalanine. D-Phenylalanine inhibits biofilm development of Pseudoalteromonas sp. SC2014[1].

HY-B1834S1

Megestrol-d5
Megestrol-d₅ is the deuterium labeled Megestrol. Megestrol is a synthetic progestin and used for the treatment of anorexia, cachexia, or an unexplained significant weight loss in patients with an acquired immunodeficiency syndrome diagnosis[1][2].

HY-Y0079S1

D-Phenylalanine-d8
D-Phenylalanine-d₈ is the deuterium labeled D-Phenylalanine. D-Phenylalanine is the synthetic dextro isomer of phenylalanine. D-Phenylalanine inhibits biofilm development of Pseudoalteromonas sp. SC2014[1].

HY-128793S1

trans-Stilbene-d12
trans-Stilbene-d₁₂ is the deuterium labeled trans-Stilbene[1]. trans-Stilbene ((E)-Stilbene) is used in the manufacturing of dye lasers, optical brighteners, non-steroidal synthetic estrogens[2].

HY-128793S2

trans-Stilbene-d10
trans-Stilbene-d₁₀ is the deuterium labeled trans-Stilbene[1]. trans-Stilbene ((E)-Stilbene) is used in the manufacturing of dye lasers, optical brighteners, non-steroidal synthetic estrogens[2].

HY-128793S3

trans-Stilbene-d2
trans-Stilbene-d₂ is the deuterium labeled trans-Stilbene[1]. trans-Stilbene ((E)-Stilbene) is used in the manufacturing of dye lasers, optical brighteners, non-steroidal synthetic estrogens[2].

HY-B0435S

Roxithromycin-d7
Roxithromycin-d₇ (RU-28965-d₇)is the deuterium labeledRoxithromycin(HY-B0435) . Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic .

HY-135389S

Desmethyl Levofloxacin-d8 hydrochloride
Desmethyl Levofloxacin-d8 hydrochloride is the deuterium labeled Desmethyl Levofloxacin. Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication .

HY-13570S

Betamethasone-d5
Betamethasone-d₅ is the deuterium labeled Betamethasone. Betamethasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activities. Betamethasone accelerates fetal lung maturation and induces gene expression and apoptosis[1][2][3][4].

HY-13604S

Cyproterone acetate-d3
Cyproterone acetate-d₃ is deuterium labeled Cyproterone acetate. Cyproterone acetate is an anti-androgen (IC50=7.1 nM) and progestogen synthetic steroid. Cyproterone acetate has affinity with progesteron and with glucocorticoidal receptors[1][2].

HY-128793S

trans-Stilbene-13C2
trans-Stilbene- ¹³C₂ is the ¹³C labeled trans-Stilbene[1]. trans-Stilbene ((E)-Stilbene) is used in the manufacturing of dye lasers, optical brighteners, non-steroidal synthetic estrogens[2].

HY-B0361S1

Aspartame-d5
Aspartame-d₅ is the deuterium labeled Aspartame. Aspartame (SC-18862) is a methyl ester of a dipeptide. Aspartame can be used as a synthetic nonnutritive sweetener. Aspartame is composed of phenylalanine (50%), aspartic acid (40%) and methanol (10%)[1][2].

HY-B0361S

Aspartame-d3
Aspartame-d₃ is the deuterium labeled Aspartame. Aspartame (SC-18862) is a methyl ester of a dipeptide. Aspartame can be used as a synthetic nonnutritive sweetener. Aspartame is composed of phenylalanine (50%), aspartic acid (40%) and methanol (10%)[1][2].

HY-B0672S

Estradiol valerianate-d9
Estradiol valerianate-d₉ is the deuterium labeled Estradiol valerianate. Estradiol valerianate (β-estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.

HY-B0672S1

Estradiol valerianate-d4
Estradiol valerianate-d₄ is the deuterium labeled Estradiol valerianate. Estradiol valerianate (β-estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.

HY-135389S1

Desmethyl Levofloxacin-d8
Desmethyl Levofloxacin-d₈ is deuterium labeled Desmethyl Levofloxacin. Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication[1].

HY-13570S1

Betamethasone-d5-1
Betamethasone-d₅-1 is deuterium labeled Betamethasone. Betamethasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activities. Betamethasone accelerates fetal lung maturation and induces gene expression and apoptosis[1][2][3][4].

HY-B0129S

Aztreonam-d6
Aztreonam-d₆ is deuterium labeled Aztreonam. Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3).

HY-B0260S

Methylprednisolone-d3
Methylprednisolone-d₃ is the deuterium labeled Methylprednisolone. Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels[3].

HY-B0260S2

Methylprednisolone-d4
Methylprednisolone-d₄ is deuterium labeled Methylprednisolone. Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels[3].

HY-B0260S3

Methylprednisolone-d7
Methylprednisolone-d₇ is deuterium labeled Methylprednisolone. Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels[3].

Cat. No.	Product Name		Classification

HY-151661

N3-L-Val-OH (CHA) L-azidovaline (CHA)		Azide
N3-L-Val-OH (CHA) is a click chemistry containing an azide group, a valine derivative. N3-L-Val-OH (CHA) can also be used as a synthetic intermediate for Valaciclovir (Valacyclovir) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-B1029

Danazol 4 Publications Verification		Alkynes
Danazol is a derivative of the synthetic steroid Ethisterone, which inhibits gonadotropin production and has a certain weak androgenic effect. Danazol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-101405

Gestrinone R 2323		Alkynes
Gestrinone (R2323) is a synthetic steroid hormone used to treat endometriosis. It inhibits leiomyoma cells with an IC₅₀ of 43.67 μM. Gestrinone is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W013172

Norgestimate		Alkynes
Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive . Norgestimate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-N7137

Norgestrel		Alkynes
Norgestrel is a synthetic analog of progesterone, a compound commonly found in oral contraceptive pill, and a powerful neuroprotective antioxidant, preventing light-induced ROS in photoreceptor cells, and cell death . Norgestrel is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-136396

Chlorempenthrin		Alkynes
Chlorempenthrin is a synthetic pyrethroid insecticide . Chlorempenthrin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-111302

Norgestrienone		Alkynes
Norgestrienone is a progestin receptor agonist. Norgestrienone is commonly used as a progesterone compound in birth control pills and can be combined with ethinylestradiol. Norgestrienone is a click chemical. It contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Azide groups. Norgestrienone can be used in the study of hereditary angioneurotic edema .

HY-B0257S1

Norgestrel-d6		Alkynes
Norgestrel-d₆ is the deuterium labeled Levonorgestrel. Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives. Norgestrel-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-16247

Apoptone HE3235		Alkynes
Apoptone, synthetic analogue of 3β-androstanediol, is an orally bioavailable anticancer agent. Apoptone is active in rodent models of prostate and breast cancer . Apoptone is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0257S

Levonorgestrel-d8 D-Norgestrel-d₈		Alkynes
Levonorgestrel-d₈ is the deuterium labeled Levonorgestrel. Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives[1][2]. Levonorgestrel-d8 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-G0018S

Norgestimate metabolite norelgestromin-d6 17-Deacetyl norgestimate-d₆; 17-Deacylnorgestimate-d₆		Alkynes
Norgestimate metabolite norelgestromin-d₆ is the deuterium labeled Norgestimate metabolite norelgestromin. Norelgestromin is a metabolite of Norgestimate, which is a progestin or synthetic progestogen. Norgestimate metabolite norelgestromin-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-139244S

Norgestimate-d6		Alkynes
Norgestimate-d₆ is the deuterium labeled Norgestimate. Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive[1][2]. Norgestimate-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-147309

16-Azidohexadecanoic acid		Azide
16-Azidohexadecanoic acid, a synthetic fatty acid, can be used as a modification marker for nucleotides and a molecular probe for fatty acid metabolism . 16-Azidohexadecanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-144585

AGD-0182		Azide
AGD-0182 is a microtubule disrupting agent. AGD-0182 is a synthetic analogue of the naturally occurring tubulin-binding molecule Dolastatin 10 . AGD-0182 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W006064

(S)-2-Aminopent-4-ynoic acid		Alkynes
(S)-2-Aminopent-4-ynoic acid is a synthetic amino acid. (S)-2-Aminopent-4-ynoic acid can be used in synthesis of folate-conjugates and corresponding metal-chelate complexes . (S)-2-Aminopent-4-ynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-115715A

EN219-alkyne		Alkynes
EN219-alkyne is an alkyne-functionalized EN219 probe. EN219 (HY-P0287A) is a moderately selective synthetic covalent ligand against an N-terminal cysteine (C8) of RNF114 with an IC₅₀ of 470 nM. EN219 inhibits RNF114-mediated autoubiquitination and p21 ubiquitination . EN219-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-108039

Bezisterim HE 3286; NE-3107		Alkynes
Bezisterim (HE 3286; NE-3107) is a synthetic derivative of a natural anti-inflammatory steroid, β-AET. Bezisterim is an orally active partial NF-κB inhibitor. HE3286 reduces proinflammatory signals, including IL-6 and matrix metallopeptidase 3. Bezisterim freely penetrates the blood brain barrier in mice. Bezisterim can be used for the research of the ulcerative colitis, arthritis, experimental autoimmune encephalomyelitis . Bezisterim is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B2091

Azidocillin		Azide
Azidocillin, a semi-synthetic Penicillin, is an orally active β-lactam antibiotic. Azidocillin bears an azide functionality and retains on-target activity within bacteria. Azidocillin can be used to research osteitis caused by dental surgery, otitis media, enterococcal septicemia and other bacterial infectious diseases . Azidocillin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-136314

DBCO-PEG4-VC-PAB-MMAE		DBCO
DBCO-PEG4-VC-PAB-MMAE consists a ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE (HY-15162). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates (ADCs). MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. DBCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-126437

Poly-L-lysine hydrobromide (MW 30000-70000) 1 Publications Verification		Polymers
Poly-L-lysine hydrobromide (MW 30000-70000) is a water-soluble synthetic polypeptide .

HY-108753A

Eteplirsen sodium AVI 4658 sodium		Antisense Oligonucleotides
Eteplirsen sodium is a synthetic antisense oligonucleotide, and can be used for Duchenne muscular dystrophy research .

HY-B0361

Aspartame 1 Publications Verification SC-18862		Sweetening Agents
Aspartame (SC-18862) is a methyl ester of a dipeptide. Aspartame can be used as a synthetic nonnutritive sweetener .

HY-150214

ODN MT01		CpG ODNs
ODN MT01 was designed based on human mitochondrial DNA sequences, which is an inhibitory ODN that promotes osteocyte differentiation. ODN MT01 could promote osteoblast maturation and activation in rats, reduce rat alveolar bone absorption caused by periodontitis, regulate the expression levels of osteogenesis-related factors.

HY-150214A

ODN MT 01 sodium		CpG ODNs
ODN MT01 sodium was designed based on human mitochondrial DNA sequences, which is an inhibitory ODN that promotes osteocyte differentiation. ODN MT01 sodium could promote osteoblast maturation and activation in rats, reduce rat alveolar bone absorption caused by periodontitis, regulate the expression levels of osteogenesis-related factors.

HY-145797

L343		Cationic Lipids
L343 is an ionizable cationic lipidoid and can be used to synthetic liposomes for systemic delivery of RNAi therapeutics.

HY-108753

Eteplirsen AVI 4658		Antisense Oligonucleotides
Eteplirsen (AVI 4658) is a synthetic antisense oligonucleotide. Eteplirsen can be used for Duchenne muscular dystrophy research .

HY-150212A

Tilsotolimod sodium		Antisense Oligonucleotides
Tilsotolimod (sodium) is a synthetic Toll-like receptor 9 (TLR9) agonist that has demonstrated antitumor activity in preclinical models.

HY-150212

Tilsotolimod		Antisense Oligonucleotides
Tilsotolimod is a synthetic Toll-like receptor 9 (TLR9) agonist that has demonstrated antitumor activity in preclinical models.

HY-Y0850O

Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed) PVA (Mw 31000-50000, 87-89% hydrolyzed); Poly(Ethenol) (Mw 31000-50000, 87-89% hydrolyzed)		Polymers
Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed) is a synthetic polymer derived from polyvinyl acetate through partial or complete hydroxylation .

HY-W440931

MPEG2000-DMG		Pegylated Lipids
MPEG2000-DMG is a synthetic lipid comprised of polyPEG and dimyristoyl glycerol. It is used in the creation of lipid nanoparticles (LNPs) for mRNA vaccines.

HY-113325

NADP Maximum Cited Publications 6 Publications Verification		Nucleotides and their Analogs
NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes .

HY-139298

L319 Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate		Cationic Lipids
L319 is an ionizable cationic lipidoid and can be used for synthetic liposomes, from the patent WO-2011153493-A2, compound 1 .

HY-112756

PEG2000-DGG		Pegylated Lipids
PEG2000-DGG is a synthetic lipid. PEG2000-DGG can be used in lipid-based nanoparticle (LNP) delivery systems .

HY-F0002

NADP sodium salt Maximum Cited Publications 6 Publications Verification Sodium NADP		Nucleotides and their Analogs
NADP sodium salt is the sodium salt form of NADP (HY-113325). NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes .

HY-F0002A

NADP disodium salt Maximum Cited Publications 6 Publications Verification Disodium NADP		Nucleotides and their Analogs
NADP disodium salt is the disodium salt form of NADP (HY-113325). NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes .

HY-150724C

ODN 1018 sodium 1018 ISS sodium		CpG ODNs
ODN 1018 sodium, an oligodeoxynucleotide, is a TLR-9 agonist. ODN 1018 sodium is also a synthetic immunostimulatory sequence that can be used as vaccine adjuvant. Sequence: 5′-TGACTGTGAACGTTCGAGATGA-3′ .

HY-144019

18:0 EPC chloride		Cationic Lipids
18:0 EPC chloride is a synthetic cationic phospholipid. 18:0 EPC chloride (at the critical synergistic concentrations of 2.34-2.93 μM) significantly improves the inactivation effect of eugenol against Escherichia coli .

HY-W048496

2'-O-(2-Methoxyethyl)-cytidine		Nucleosides and their Analogs
2'-O-(2-Methoxyethyl)-cytidine is a synthetic oligonucleotide conversed from uridine. 2'-O-(2-Methoxyethyl)-uridine has the potential for chemotherapeutic agents development .

HY-W048495

2'-O-(2-Methoxyethyl)-uridine		Nucleosides and their Analogs
2'-O-(2-Methoxyethyl)-uridine is a synthetic oligonucleotide conversed from uridine. 2'-O-(2-Methoxyethyl)-uridine has the potential for chemotherapeutic agents development .

HY-150724

ODN 1018 1018 ISS		CpG ODNs
ODN 1018 (1018 ISS), an oligodeoxynucleotide, is a TLR-9 agonist. ODN 1018 is also a synthetic immunostimulatory sequence that can be used as vaccine adjuvant. Sequence: 5′-TGACTGTGAACGTTCGAGATGA-3′ .

HY-148412A

Monarsen sodium EN101 sodium; ODN 7040 sodium; BL 7040 sodium		Antisense Oligonucleotides
Monarsen sodium is a synthetic 20-base antisense oligodeoxynucleotide directed against the human AChE gene. Monarsen sodium is used in the study of Autoimmune myasthenia gravis (MG), a neuromuscular disorder caused by autoantibodies directed against the acetylcholine receptor (AChR).

HY-Y0850A3

Polyvinyl alcohol, MW 64000 (Excipient) PVA, MW 64000 (Excipient)		Emulsifiers
Polyvinyl alcohol, MW 64000 (PVA, MW 64000) (Excipient) is a water-soluble synthetic polymer with a molecular weight of 64000. Polyvinyl alcohol hydrogel is commonly used as a versatile excipient in biomedical applications including vascular grafting .

HY-148412

Monarsen EN101; ODN 7040; BL 7040		Antisense Oligonucleotides
Monarsen (EN101) is a synthetic 20-base antisense oligodeoxynucleotide directed against the human AChE gene. Monarsen is used in the study of Autoimmune myasthenia gravis (MG), a neuromuscular disorder caused by autoantibodies directed against the acetylcholine receptor (AChR).

HY-109541

1,2-Dimyristoyl-sn-glycero-3-phosphocholine DMPC; Dimyristoyl phosphatidylcholine		Phospholipids
1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine is used for the study of lipid monolayers and bilayers .

HY-148230

TFEB Decoy ODN sodium		Decoy ODNs
TFEB Decoy ODN sodium is a synthetic oligonucleotide with a hairpin ring structure, which were designed to inhibit Transcription factor EB (TFEB). TFEB decoy ODN inhibited fibrosis and autophagy in a UUO mouse model. The TFEB decoy ODNs also showed anti-inflammatory effects.

HY-W800805

DOPE-Mal		Phospholipids
DOPE-Mal is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions with a terminal maliemide group. The maleimide group will react with a thiol group to form a covalent bond. The hydrophilic PEG spacer increases solubility in aqueous media.

HY-131652

1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine 16:0 Diether PC		Phospholipids
1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine (16:0 Diether PC) is a synthetic ether-linked phospholipid containing hexadecyl groups at the sn-1 and sn-2 positions. It is commonly used in the generation of liposomes and artificial membranes to study membrane dynamics.

HY-126403

Ethoxylated hydrogenated castor oil PEG-40 hydrogenated castor oil; Macrogolglycerol hydroxystearate; Castor oil, hydrogenated, polyethoxylated		Thickeners
Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo .

HY-150217

CpG ODN 10101 ODN 10101		CpG ODNs
CpG ODN 10101, a synthetic oligodeoxynucleotide (ODN), is a toll-like receptor 9 (TLR9) agonist. CpG ODN 10101 is a potent inducer of cytokine/chemokine expression ex vivo when used in combination with HH2(VQLRIRVAVIRA-NH2). CpG ODN 10101 induces IFN- secretion from dendritic cells (DCs) and stimulates B-cells.CpG ODN 10101 has antiviral and immunomodulatory properties that can influence chronic infection with HCV .

HY-150217A

CpG ODN 10101 sodium 1 Publications Verification ODN 10101 sodium		CpG ODNs
CpG ODN 10101 sodium, a synthetic oligodeoxynucleotide (ODN), is a toll-like receptor 9 (TLR9) agonist. CpG ODN 10101 sodium is a potent inducer of cytokine/chemokine expression ex vivo when used in combination with HH2(VQLRIRVAVIRA-NH2). CpG ODN 10101 sodium induces IFN- secretion from dendritic cells (DCs) and stimulates B-cells.CpG ODN 10101 sodium has antiviral and immunomodulatory properties that can influence chronic infection with HCV .

HY-131119

Dimethyldioctadecylammonium bromide Dioctadecyldimethylammonium bromide; DODAB		Cationic Lipids
Dimethyldioctadecylammonium bromide is a synthetic cationic lipid commonly used in gene delivery and vaccine development. Also known as DODAB or DDAB, it consists of a positively charged ammonium head group and two long hydrophobic tails. These properties make it useful for forming liposomes and other lipid-based nanoparticles that can efficiently deliver genetic material into cells. In addition to its applications in biotechnology, DDAB is also used in surfactants, emulsifiers and fabric softeners. However, due to its potential toxicity and irritation, extreme care should be taken when handling DDAB.

HY-132595

Teprasiran QPI-1002		siRNAs
Teprasiran (QPI-1002) is a small interfering RNA that temporarily inhibits p53-mediated cell death that underlies acute kidney injury (AKI) .

HY-132595A

Teprasiran sodium QPI-1002 sodium		siRNAs
Teprasiran sodium is a small interfering RNA that temporarily inhibits p53-mediated cell death that underlies acute kidney injury (AKI) .

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