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Results for "

Elsamitrucin

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16192
    Elsamitrucin

    BMY-28090; SPI-28090; Antibiotic BBM 2478A

    		 Bacterial Infection
    Elsamitrucin, derived from actinomycete fermentation, exhibits potent cytotoxicity against a range of murine and human tumor cell lines in vitro, with IC50 values ranging from <0.02 to 3.25 μg/ml after 72-hour exposures. In vivo studies demonstrated significant antitumor activity in various experimental murine tumor models, including P388 leukemia, L1210 leukemia, B16 melanoma, and M5076 sarcoma, when administered intraperitoneally as a water-insoluble free base or as water-soluble lactate or succinate salts. Elsamitrucin also showed efficacy against human MX-1 mammary tumor and HCT116 colon tumor xenografts, highlighting its broad-spectrum cytotoxicity and potential as an antitumor agent across different tumor types and models .
    Elsamitrucin
  • HY-158820
    Cosdosiran

    QPI-1007

    		 Small Interfering RNA (siRNA) Caspase Cardiovascular Disease
    Cosdosiran is a chemically modified siRNA designed to temporarily inhibit expression of the caspase 2 protein and can be used for the study of nonarteritic anterior ischemic optic neuropathy and other optic neuropathies such as glaucoma that result in the death of retinal ganglion cells.?
    Cosdosiran
  • HY-158820A
    Cosdosiran sodium

    QPI-1007 sodium

    		 Small Interfering RNA (siRNA) Caspase Cardiovascular Disease
    Cosdosiran sodium is a chemically modified siRNA designed to temporarily inhibit expression of the caspase 2 protein and can be used for the study of nonarteritic anterior ischemic optic neuropathy and other optic neuropathies such as glaucoma that result in the death of retinal ganglion cells.?
    Cosdosiran sodium
  • HY-E70364
    IgdE protease

    		Biochemical Assay Reagents Inflammation/Immunology
    IgdE protease is a cysteine protease, which is initially isolated from Streptococcus agalactiae. IgdE protease digests monoclonal antibodies (mAbs) of the IgG1 type specifically at their upper hinge region, produces Fc/2, hinge peptide dimers, and Fab fragment. IgdE protease can be used in disulfide bonds and free thiol analysis, as it requires no reducing agents for cleavage .
    IgdE protease

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