2. One-stop Drug Screening
  3. Screening Libraries
  4. Bioactive Compound Series
  5. Drug Repurposing Series
  6. FDA-Approved Drug Library
FDA-Approved Drug Library

Cat. No.: HY-L022

New drug development is a time-consuming and high-cost process. Drug repurposing (also called drug repositioning, reprofiling or re‑tasking) offers various advantages over developing an entirely new drug for a given indication. First, the risk of failure is lower. Second, the time frame for drug development can be reduced. Third, less investment is needed. Approved drugs have identified bioactivities, good pharmacokinetic characteristics and safety which are suitable for drug repurposing.

MCE owns a unique collection of 3,061 approved compounds which have been completed extensive preclinical and clinical studies and have well-characterized bioactivities, safety and bioavailability properties. MCE FDA-Approved Drug Library is a good tool for drug repurposing which could dramatically accelerate drug development.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Description & Advantages

•   A unique collection of 3,061 approved drugs for high throughput screening (HTS) and high content screening (HCS).

•   Used in the research of oncology, cardiology, anti-inflammatory, immunology, dermatology, endocrinology, neurology, and more.

•   A useful tool for researching new targets of marketed old drugs.

•   All compounds have been approved by the FDA, EMA and other countries.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.

  FDA-Approved Drug Library FDA-Approved Drug Library Mini (Cat. No.: HY-L022M)
Size 30, 50, 100, and 200 μL in DMSO 10 μL in DMSO
Package 96-Well Format Sample Storage Tube With Screw Cap 96-well microplate with peelable foil seal
Delivery Date About one month Within three days
Price Per Set High Low
Preparation For Use If there is no robot, each tube needs to be manually opened Tear off the seal film on the microplate

Product Details

Formulation:

A collection of 3,061 marketed drugs supplied as pre-dissolved Solutions or Solid
Solution: 2,979 compounds supplied in 10 mM solution, 58 compounds supplied in 2 mM solution, 24 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

Composition

COX (92)

HIV (91)

mAChR (76)

VEGFR (35)

HCV (34)

nAChR (32)

EGFR (30)

HSV (30)

iGluR (27)

PDGFR (25)

HBV (24)

PPAR (22)

c-Kit (21)

FGFR (21)

JAK (21)

Akt (15)

CDK (15)

STAT (15)

ERK (14)

MMP (14)

PARP (14)

HDAC (13)

PI3K (13)

FLT3 (12)

Src (12)

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Compound Customization
  •  Specific Compounds
  •  Quantities
  •  Plate Map
  •  Concentration
  •  Form (Solid or Solution)
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    Product Name:
    FDA-Approved Drug Library
    Cat. No.:
    HY-L022
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack
    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack

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