2. Recombinant Proteins
  3. Viral Proteins
  4. Dengue Virus Proteins

Dengue Virus Proteins

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Dengue virus (DENV) is an important human pathogen and contains four serotypes (DENV-1–4) which can be transmitted by mosquitos. The dengue viruses belongs to the genus Flavivirus in the family Flaviviridae. The dengue virus genome is a positive-sense, single stranded RNA with a size of 11 kb that contains one open reading frame. It is translated as a single, long polypeptide and then cut into ten proteins, including three structural (capsid [C], membrane [M], and envelope [E]) and seven nonstructural (NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5) proteins. The nonstructural proteins play roles in viral replication and assembly. The structure of the dengue virus is roughly spherical, with a diameter of approximately 50 nm (1 nm is one millionth of 1 mm). The core of the virus is the nucleocapsid, a structure that is made of the viral genome along with C proteins. The nucleocapsid is surrounded by a membrane called the viral envelope, a lipid bilayer that is taken from the host. Embedded in the viral envelope are 180 copies of the E and M proteins that span through the lipid bilayer. These proteins form a protective outer layer that controls the entry of the virus into human cells.

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Cat. No. Product Name / Synonyms Species Source
  • HY-P73740
    NS1 Protein, Dengue virus 2 (HEK293, His)

    DEN-2; Dengue NS1 protein; Dengue virus Type 2; DENV2; DENV2-NS1

    		Virus HEK293
    NS5 Protein is part of the flavivirus RNA replication complex (RC) composed of viral non-structural proteins and host-cell cofactors. NS5 is the largest flavivirus protein, the most conserved, which act as two domains, the RNA-dependent RNA polymerase (RdRp) and RNA methyltransferase enzyme (MTase). NS5 plays a fundamental role in flavivirus replication, viral RNA methylation, RNA polymerization, and host immune system evasion. NS1 Protein, Dengue virus 2 (HEK293, His) is the recombinant Virus-derived NS1 protein, expressed by HEK293 , with N-His labeled tag.
  • HY-P74190
    E/Envelope Protein, Dengue virus 4 (395a.a, sf9, His)

    E Protein; DENV; Dengue virus (DENV) (type 4, strain Philippines/H241/1956) E / Envelope Protein (ECD, His Tag)

    		Virus Sf9 insect cells
    The NS1 protein plays a key role in viral budding, association with cell membranes, and facilitating the assembly of viral RNA into nucleocapsids to form mature viral particles.During entry, NS1 induces genome penetration into the host cytoplasm.E/Envelope Protein, Dengue virus 4 (395a.a, sf9, His) is the recombinant Virus-derived E/Envelope protein, expressed by Sf9 insect cells , with C-His labeled tag.
  • HY-P74194
    E/Envelope Protein, Dengue virus 2 (429a.a, sf9, His)

    E Protein; DENV; Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E / Envelope Protein (ECD, His Tag)

    		Virus Sf9 insect cells
    E/Envelope Protein, Dengue virus 2 (429a.a, sf9, His) is the recombinant Virus-derived E/Envelope protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of E/Envelope Protein, Dengue virus 2 (429a.a, sf9, His) is 429 a.a., with molecular weight of ~49.2 kDa.
  • HY-P74196
    E/Envelope Protein, Dengue virus 2 (102a.a, P.pastoris, His)

    E Protein; DENV; Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E / Envelope Protein (Domain III, His Tag)

    		Virus P. pastoris
    E/Envelope Protein, Dengue virus 2 (102a.a, P.pastoris, His) is the recombinant Virus-derived E/Envelope protein, expressed by P. pastoris , with C-His labeled tag. The total length of E/Envelope Protein, Dengue virus 2 (102a.a, P.pastoris, His) is 102 a.a., with molecular weight of ~17.1 kDa.
  • HY-P75290
    NS1 Protein, Dengue virus 1 (HEK293, His)

    DENV-NS1 Protein; DENV; Dengue virus (DENV) (type 1, strain US/Hawaii/1944) DENV-NS1 Protein

    		Virus HEK293
    The NS1 protein plays a key role in viral budding, association with cell membranes, and facilitating the assembly of viral RNA into nucleocapsids to form mature viral particles.During entry, NS1 induces genome penetration into the host cytoplasm.NS1 Protein, Dengue virus 1 (HEK293, His) is the recombinant Virus-derived NS1 protein, expressed by HEK293 , with N-His labeled tag.
  • HY-P75704
    NS5 Protein, Dengue virus 2 (His)

    Dengue virus DENV-2 (strain New Guinea C) NS5 (methyltransferase domain) / Nonstructural protein 5 Protein; DENV-NS5 Protein; DENV

    		Virus E. coli
    NS5 Protein is part of the flavivirus RNA replication complex (RC) composed of viral non-structural proteins and host-cell cofactors. NS5 is the largest flavivirus protein, the most conserved, which act as two domains, the RNA-dependent RNA polymerase (RdRp) and RNA methyltransferase enzyme (MTase). NS5 plays a fundamental role in flavivirus replication, viral RNA methylation, RNA polymerization, and host immune system evasion. NS5 Protein, Dengue virus 2 (His) is the recombinant Virus-derived NS5 protein, expressed by E. coli , with N-His labeled tag. The total length of NS5 Protein, Dengue virus 2 (His) is 296 a.a., with molecular weight of ~35.5 kDa.
  • HY-P73738
    NS1 Protein, Dengue virus 4 (HEK293, His)

    DEN-4; Dengue Virus 4 NS1; Dengue virus Type 4; DENV4; DENV4-NS1

    		Virus HEK293
    The NS1 protein plays a key role in viral budding, association with cell membranes, and facilitating the assembly of viral RNA into nucleocapsids to form mature viral particles. During entry, NS1 induces genome penetration into the host cytoplasm. NS1 Protein, Dengue virus 4 (HEK293, His) is the recombinant Virus-derived NS1 protein, expressed by HEK293 , with N-His labeled tag.
  • HY-P73739
    NS1 Protein, Dengue virus 3 (HEK293, His)

    DEN-3; Dengue Virus 3 NS1; Dengue virus Type 3; DENV3; DENV3-NS1

    		Virus HEK293
    The NS1 protein plays a key role in viral budding, association with cell membranes, and facilitating the assembly of viral RNA into nucleocapsids to form mature viral particles. During entry, NS1 induces genome penetration into the host cytoplasm. NS1 Protein, Dengue virus 3 (HEK293, His) is the recombinant Virus-derived NS1 protein, expressed by HEK293 , with N-His labeled tag.
  • HY-P74191
    E/Envelope Protein, Dengue virus 4 (101a.a, HEK293, His)

    E Protein; DENV; Dengue virus (DENV) (type 4, strain Philippines/H241/1956) E / Envelope Protein (aa 579-679, His Tag)

    		Virus HEK293
    The NS1 protein plays a key role in viral budding, association with cell membranes, and facilitating the assembly of viral RNA into nucleocapsids to form mature viral particles.During entry, NS1 induces genome penetration into the host cytoplasm.E/Envelope Protein, Dengue virus 4 (101a.a, HEK293, His) is the recombinant Virus-derived E/Envelope protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P74192
    E/Envelope Protein, Dengue virus 3 (429a.a, HEK293, His)

    E Protein; DENV; Dengue virus (DENV)(type 3, strain Philippines/H87/1956) E / Envelope Protein (aa 247-675, ECD, His Tag)

    		Virus HEK293
    The NS1 protein plays a key role in viral budding, association with cell membranes, and facilitating the assembly of viral RNA into nucleocapsids to form mature viral particles. During entry, NS1 induces genome penetration into the host cytoplasm. E/Envelope Protein, Dengue virus 3 (429a.a, HEK293, His) is the recombinant Virus-derived E/Envelope protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P74193
    E/Envelope Protein, Dengue virus 2 (103a.a, P.pastoris, His)

    E Protein; DENV; Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E / Envelope Protein (Domain III, His Tag)

    		Virus P. pastoris
    E/Envelope Protein, Dengue virus 2 (103a.a, P.pastoris, His) is the recombinant Virus-derived E/Envelope protein, expressed by P. pastoris , with C-His labeled tag.
  • HY-P74195
    E/Envelope Protein, Dengue virus 2 (399a.a, T76R, Q77E, W101R, L107R, sf9, His)

    E Protein; DENV; Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E / Envelope Protein (His Tag)

    		Virus Sf9 insect cells
    E/Envelope Protein, Dengue virus 2 (399a.a, T76R, Q77E, W101R, L107R, sf9, His) is the recombinant Virus-derived E/Envelope protein, expressed by Sf9 insect cells , with C-His labeled tag.
  • HY-P74197
    E/Envelope Protein, Dengue virus 1 (101a.a, sf9, His)

    E Protein; DENV; Envelope; Dengue virus (DENV) (type 1, strain US/Hawaii/1944) E/Envelope Protein Domain III

    		Virus Sf9 insect cells
    The NS1 protein plays a key role in viral budding, association with cell membranes, and facilitating the assembly of viral RNA into nucleocapsids to form mature viral particles.During entry, NS1 induces genome penetration into the host cytoplasm.E/Envelope Protein, Dengue virus 1 (101a.a, sf9, His) is the recombinant Virus-derived E/Envelope protein, expressed by Sf9 insect cells , with C-His labeled tag.
  • HY-P74198
    E/Envelope Protein, Dengue virus 1 (101a.a, HEK293, His)

    E Protein; DENV; DENV Envelope / DENV-E Protein (His Tag)

    		Virus HEK293
    The NS1 protein plays a key role in viral budding, association with cell membranes, and facilitating the assembly of viral RNA into nucleocapsids to form mature viral particles.During entry, NS1 induces genome penetration into the host cytoplasm.E/Envelope Protein, Dengue virus 1 (101a.a, HEK293, His) is the recombinant Virus-derived E/Envelope protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P75291
    Dengue virus Capsid Protein (His)

    death-domain associated protein; Dengue virus DENV-2 (Strain New Guinea C) Capsid protein / DENV-C Protein

    		Virus E. coli
    Dengue virus Capsid Protein (His) is the recombinant Virus-derived Dengue virus Capsid protein, expressed by E. coli , with N-His labeled tag. The total length of Dengue virus Capsid Protein (His) is 100 a.a., with molecular weight of ~14 kDa.
Cat. No. Product Name Effect Purity