2. Signaling Pathways
  3. Apoptosis
  4. Transferrin Receptor

Transferrin Receptor

TfR; CD71

 

Transferrin Receptor Related Products (20):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-P3267
    Transferrins
    		≥99.0%
    Transferrin, a blood-plasma glycoprotein, is a target ligand for transferrin receptor. Transferrins can bind to and mediate the transport of iron.
    Transferrins
  • HY-107928
    Iron dextran
    Iron dextran (Fe dextran) can be used in the study of iron-deficiency anemia in animals.
    Iron dextran
  • HY-NP011
    Holo-Human transferrin
    Holo-Human transferrin is a glycoprotein with a branched sugar chain that mediates the transport of iron from plasma to cells.
    Holo-Human transferrin
  • HY-B1651
    Iron(II) fumarate
    Iron (II) fumarate is an orally effective active dietary supplement. Iron (II) fumarate can alleviate metabolic damage and damage to silkworms caused by cypermethrin (HY-123178). Iron (II) fumarate can be used for research on iron deficiency anemia.
    Iron(II) fumarate
  • HY-P2297A
    TfR-T12 TFA
    		99.10%
    TfR-T12 TFA is a BBB-penetrated transferrin receptor (TfR) binding peptide, displaying a binding affinity in the nM range.
    TfR-T12 TFA
  • HY-159569
    TfR-1-IN-1
    		Inhibitor
    TfR-1-IN-1 (compound C4) is an inhibitor of transferrin receptor 1 (TfR-1) with anticancer activity. TfR-1-IN-1 strongly increases intracellular iron (II) levels as a driving force for the induction of ferroptosis. TfR-1-IN-1 significantly reduces the metabolic activity of ovarian cancer (A2780cis), breast cancer (MDA-MB 231), and leukemia (HL-60) cell lines with IC50 values ​​of 0.51, 0.46, and 0.48 μM, respectively.
    TfR-1-IN-1
  • HY-P991047
    Anti-CD71/TfR1 Antibody
    		Inhibitor ≥99.0%
    Anti-CD71/TfR1 Antibody (JR-141 antibody (uncoupled from iduronate 2-sulfatase)) is a humanized anti-human transferrin receptor (CD71; TfR) antibody. Anti-CD71/TfR1 Antibody is the antibody part of the fusion protein Pabinafusp alfa (HY-P99797). The recommend isotype control of Anti-CD71/TfR1 Antibody: Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-CD71/TfR1 Antibody
  • HY-P990856
    Anti-CD71 Antibody (OKT-9)
    		Inhibitor
    Anti-CD71 Antibody (OKT-9) is a kind of mouse IgG1κ chimeric antibody, targeting to human CD71. The recommend isotype control of Anti-CD71 Antibody (OKT-9): Mouse IgG1 kappa, Isotype Control (HY-P99977).
    Anti-CD71 Antibody (OKT-9)
  • HY-P3267A
    Apo-Bovine Transferrin
    		Activator
    Apo-Bovine Transferrin refers to iron free Transferrin (HY-P3267), serves as Transferrin receptor ligand and mediates iron release from endothelial cells. Apo-Transferrin indicates an iron deficient environment, can directly bind to hephaestin, which can convert Fe2+ to Fe3+. Apo-Transferrin mediates iron efflux most likely in cooperation with ferroportin 1.
    Apo-Bovine Transferrin
  • HY-P99797
    Pabinafusp alfa
    Pabinafusp alfa (JR-141) is a transferrin receptor-targeting antibody consisting of Iduronate 2-sulfatase (HY-P76399) and an anti-human transferrin receptor antibody. Pabinafusp alfa is blood-brain permeable and prevents heparan sulfate (HS) deposition in the central nervous system of mucopolysaccharidosis II (MPS II) mice. Pabinafusp alfa improves learning and prevents central nervous system neuronal damage in mice.
    Pabinafusp alfa
  • HY-130078
    Ferrous bisglycinate
    		≥98.0%
    Ferrous bisglycinate is an orally active iron fortificants and therapeutic iron supplements. Ferrous bisglycinate can be used for the research of iron deficiency anemia.
    Ferrous bisglycinate
  • HY-P990129
    Anti-Mouse CD71/TfR1 Antibody (8D3)
    		Inhibitor
    Anti-Mouse CD71/TfR1 Antibody (8D3) is a rat-derived IgG2a type antibody inhibitor, targeting to mouse CD71/TfR1.
    Anti-Mouse CD71/TfR1 Antibody (8D3)
  • HY-P2314
    HAIYPRH hydrochloride
    		99.97%
    HAIYPRH hydrochloride, a targeting ligand, can specially bind to transferrin receptor (TfR). HAIYPRH hydrochloride can mediate the transport of nanocarriers across the blood-brain barrier.
    HAIYPRH hydrochloride
  • HY-P990051
    Delpacibart
    		Inhibitor
    Delpacibart is a humanized IgG1κ antibody targeting TFRC. TFRC is the most important membrane protein that regulates intracellular iron transport processes.
    Delpacibart
  • HY-P2297
    TfR-T12
    		99.11%
    TfR-T12 is a BBB-penetrated transferrin receptor (TfR) binding peptide, displaying a binding affinity in the nM range.
    TfR-T12
  • HY-B1651R
    Iron(II) fumarate (Standard)
    Iron(II) fumarate (Standard) is the analytical standard of Iron(II) fumarate. This product is intended for research and analytical applications. Iron(II) fumarate (Ferrous fumarate) is the iron(II) salt of fumaric acid. Iron(II) fumarate is an orally active dietary supplement and has the potential for iron deficiency anemia treatment.
    Iron(II) fumarate (Standard)
  • HY-P990780
    Zeleciment
    Zeleciment is an anti-TFRC IgG1κ monoclonal antibody.
    Zeleciment
  • HY-115832
    Ap44mSe
    Ap44mSe is a selenosemicarbazone that effectively depletes cellular Fe, resulting in transferrin receptor-1 up-regulation, ferritin down-regulation, and increased expression of the potent metastasis suppressor, N-myc downstream regulated gene-1. Ap44mSe forms redox active Cu complexes that target the lysosome to induce lysosomal membrane permeabilization.
    Ap44mSe
  • HY-P99694
    Lepunafusp alfa
    		Inhibitor
    Lepunafusp alfa (JR-171) is a BBB-penetrable fusion protein consisting of J-Brain Cargo and IDUA (a lysosomal enzyme, α-L-iduronidase). Lepunafusp alfa can reduce concentration of heparan sulfate (HS) and dermatan sulfate (DS). Lepunafusp alfa can be used for research of mucopolysaccharidosis type I.
    Lepunafusp alfa
  • HY-D2426
    Cy3-Transferrin
    Cy3-Transferrin is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Transferrin (HY-P3267). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Transferrin, a blood-plasma glycoprotein, is a target ligand for transferrin receptor. Transferrin can bind to and mediate the transport of iron.
    Cy3-Transferrin