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Recombinant protein is a protein encoded by a recombinant DNA that has been cloned in a system that supports expression of the gene and translation of mRNA. The host cells used for recombinant protein production can be derived from bacteria, mammalian cell, insect and yeast. Recombinant proteins have been widely used in most hot research areas such as immune checkpoints, antibody drug targets, CAR-T cell therapy targets, Fc receptors, influenza viral proteins and cytokines. MedChemExpress (MCE) offers a comprehensive catalog of recombinant proteins with excellent lot-to-lot consistency, superior activity and significantly low endotoxin levels for a variety of applications, including cell growth and differentiation, cell signaling, studies involving disease onset and progression and biopharmaceutical target discovery, protein structure and function analysis. MCE recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. Product quality is the key to our success and we take pride in offering only the highest-grade products. Product identity, quality, purity and biological activity are assured by our robust quality control and assurance policies, programs and procedures.
Fibronectin is a glycoprotein located in the extracellular matrix that can bind to collagen, fibrin, heparin, DNA, and actin. Fibronectin is involved in cell adhesion, movement, conditioning, wound healing, and maintaining cell shape. Additionally, by binding to the LILRB4 receptor, Fibronectin can inhibit monocyte activation mediated by FCGR1A/CD64, thereby exerting immune regulatory effects. Human Fibronectin is a recombinant protein dimer complex with a full length of 573 amino acids (P1270-S1546 & A1721-T2016), expressed in E. coli and is untagged.
The SLPI protein is an acid-stable protease inhibitor that has shown strong affinity for trypsin, chymotrypsin, elastase, and cathepsin G in multiple studies. It plays a critical regulatory role in inflammatory and immune responses following bacterialinfection and Listeria monocytogenes infection. SLPI Protein, Human (107a.a, Sf9, His) is the recombinant human-derived SLPI protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of SLPI Protein, Human (107a.a, Sf9, His) is 107 a.a..
Thioredoxin/TXN protein participates in multiple redox reactions, utilizing its active center dithiol for reversible oxidation and disulfide bond formation. It catalyzes important dithiol-disulfide exchange and plays a key role in S-nitrosylation of cysteine residues in response to intracellular nitric oxide. Thioredoxin/TXN Protein, Human (Solution) is the recombinant human-derived Thioredoxin/TXN protein, expressed by E. coli , with tag free. The total length of Thioredoxin/TXN Protein, Human (Solution) is 105 a.a., with molecular weight of ~14 kDa.
Fibronectin binds collagen, fibrin, heparin, DNA, and actin. It is involved in cell adhesion, motility, opsonization, wound healing and maintenance of cell shape. Fibronectin Protein, Human (HEK293, His) is the recombinant human-derived Fibronectin protein, expressed by HEK293 , with C-His labeled tag.
FRP1; FrzA; SARP-2; secreted frizzled-related protein 1; sFRP1
Human
HEK293
SFRP1 protein is a soluble Frizzled-related protein (sFRP) that regulates Wnt signaling by directly interacting with Wnt, affecting cell growth and differentiation. Notably, it reduces intracellular β-catenin levels and affects Wnt pathway components. SFRP1 Protein, Human (HEK293, His) is the recombinant human-derived SFRP1 protein, expressed by HEK293 , with C-His labeled tag.
Dickkopf-related protein 1; Dickkopf-1; Dkk-1; SK; DKK1
Mouse
HEK293
DKK-1 protein antagonizes canonical Wnt signaling by inhibiting LRP5/6-Wnt interaction and forming a ternary complex with KREMEN, thereby promoting LRP5/6 internalization. In addition to its Wnt-dependent role, DKK1 has Wnt-independent anti-apoptotic activity by inhibiting the pro-apoptotic function of KREMEN1. DKK-1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived DKK1 protein, expressed by HEK293 , with C-His labeled tag.
SPARC; Basement-Membrane Protein 40; BM-40; Osteonectin; ON; Secreted Protein Acidic and Rich in Cysteine; SPARC; ON
Human
HEK293
SPARC proteins are essential for lipid transport and are involved in the production, transformation, and clearance of plasma lipoproteins. It interacts with different particles, shows a preference for HDL, and binds to cellular receptors such as LDLR and VLDLR to promote the uptake of APOE-containing lipoproteins. SPARC Protein, Human (HEK293, His) is the recombinant human-derived SPARC protein, expressed by HEK293 , with C-6*His labeled tag. The total length of SPARC Protein, Human (HEK293, His) is 286 a.a., with molecular weight of ~38.0 kDa.
Podoplanin plays a crucial role in cell migration and adhesion by interacting with various partners. It promotes platelet activation and aggregation by binding to CLEC1B, but attenuates platelet aggregation and lung metastasis by interacting with CD9. Podoplanin Protein, Mouse (sf9, His) is the recombinant mouse-derived Podoplanin protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Podoplanin Protein, Mouse (sf9, His) is 133 a.a., with molecular weight of ~25 kDa.
SPARC Protein, Human is a Ca2+-binding glycoprotein that is differentially associated with morphogenesis, remodeling, cellular migration, and proliferation.
Dickkopf-related protein 1; Dickkopf-1; Dkk-1; SK; DKK1
Human
HEK293
DKK-1 Proteinas are potent antagonists of canonical Wnt signaling, inhibiting LRP5/6-Wnt interactions and forming a ternary complex with KREMEN to promote LRP5/6 internalization.In addition to its proapoptotic function by antagonizing KREMEN1 independently of Wnt, DKK-1 also exhibits antiapoptotic activity.DKK-1 Protein, Human (HEK293, Fc) is the recombinant human-derived DKK-1 protein, expressed by HEK293 , with C-hFc labeled tag.
Galectin-1/LGALS1 is a lectin that binds β-galactoside and complex carbohydrates and regulates apoptosis, proliferation, and differentiation. It inhibits CD45phosphatase activity, blocks Lyn kinase dephosphorylation, and induces T cell apoptosis. Galectin-1/LGALS1 Protein, Human is the recombinant human-derived Galectin-1/LGALS1 protein, expressed by E. coli , with tag free.
RBP4 protein acts as a retinol-binding protein, essential for transporting retinol in blood plasma. It facilitates the delivery of retinol from the liver to peripheral tissues and likely transfers bound all-trans retinol to STRA6 for cell membrane transport. Interactions with TTR prevent kidney glomeruli filtration loss. Direct interaction with STRA6 underscores RBP4's role in intricate retinol transport and distribution processes in the body. RBP4 Protein, Human (HEK293, hFc) is the recombinant human-derived RBP4 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of RBP4 Protein, Human (HEK293, hFc) is 183 a.a., with molecular weight of ~50 kDa.
Glypican-1 is a cell surface proteoglycan containing heparan sulfate that binds alpha-4 (V) collagen and aids in Schwann cell myelination. Glypican-1/GPC1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Glypican-1/GPC1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Glypican-1/GPC1 Protein, Mouse (HEK293, His) is 506 a.a., with molecular weight of ~60 kDa.
The transthyretin/TTR protein is a thyroid hormone binder that may be critical for transporting thyroxine from the bloodstream to the brain. Its structure is a homotetramer, forming a dimer of dimers, and its central channel is suggested to play a role in thyroxine binding and transport. Transthyretin/TTR Protein, Human (HEK293, Fc-Myc) is the recombinant human-derived Transthyretin/TTR protein, expressed by HEK293 , with C-hFc, C-Myc labeled tag. The total length of Transthyretin/TTR Protein, Human (HEK293, Fc-Myc) is 127 a.a., with molecular weight of ~47 kDa.
Apolipoprotein AI plays a key role in reverse cholesterol transport, promoting cholesterol efflux from tissues and acting as a cofactor for lecithin cholesterolacyltransferase (LCAT). It forms homodimers and participates in the SPAP complex, which is essential for sperm motility, interacting with both NAXE and CLU. Apolipoprotein A-I/APOA1 Protein, Human (HEK293, Fc) is the recombinant human-derived Apolipoprotein A-I/APOA1 protein, expressed by HEK293 , with C-hFc labeled tag.
The apolipoprotein AI (APOA1) protein is key to reverse cholesterol transport, promoting tissue efflux, and serves as an important cofactor for lecithin cholesterolacyltransferase (LCAT), promoting cholesterol excretion. As a homodimer, APOA1 is a component of the sperm activating protein complex (SPAP), interacts with APOA1BP, CLU, NDRG1, SCGB3A2, NAXE and YJEFN3, exhibiting multiple molecular associations. Apolipoprotein A-I/APOA1 Protein, Mouse (246a.a, HEK293, Fc) is the recombinant mouse-derived Apolipoprotein A-I/APOA1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Apolipoprotein A-I/APOA1 Protein, Mouse (246a.a, HEK293, Fc) is 246 a.a., with molecular weight of ~58 kDa.
The COMP protein is critical for cartilage integrity and interacts with extracellular matrix proteins to promote the connection of chondrocytes to the cartilage matrix through integrin receptors. Its role in the pathogenesis of osteoarthritis emphasizes the significance of joint health. COMP Protein, Human (HEK293, His) is the recombinant human-derived COMP protein, expressed by HEK293 , with C-His labeled tag. The total length of COMP Protein, Human (HEK293, His) is 737 a.a., with molecular weight of 120-130 kDa.
High mobility group protein B1; HMG-1; HMGB1; HMG1
Human
E. coli
The multifunctional and redox-sensitive HMGB1/HMG-1 protein plays multiple roles in cellular compartments. In the nucleus, it serves as a major chromatin-associated non-histone protein involved in key processes such as replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair, and genome stability. HMGB1/HMG-1 Protein, Human (102a.a, His) is the recombinant human-derived HMGB1/HMG-1 protein, expressed by E. coli , with N-His, N-6*His labeled tag. The total length of HMGB1/HMG-1 Protein, Human (102a.a, His) is 102 a.a., with molecular weight of ~15 kDa.
