1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. Interleukin & Receptors

Interleukin & Receptors

Interleukins (ILs) are a group of cytokine first seen to be expressed by leukocytes alone but have later been found to be produced by many other body cells. Interleukins have both paracrine and autocrine function. They can elicit many reactions in cells and tissues by binding to high-affinity receptors in cell surfaces. Interleukins regulate pro- and anti-inflammatory, immune cell differentiation and activation.

Cat. No. Product Name / Synonyms Species Source
  • HY-P7077
    IL-2 Protein, Mouse

    rMuIL-2; IL2; T-cell Growth Factor; TCGF; Aldesleukin

    Mouse E. coli
    IL-2 protein is mainly produced by activated CD4-positive helper T cells and plays an important role in immune response and tolerance. Binding to IL-2R induces downstream signaling through JAK1 and JAK3 phosphorylation, thereby activating various pathways, including STAT, PI3K, and MAPK. IL-2 Protein, Mouse is the recombinant mouse-derived IL-2 protein, expressed by E. coli.
  • HY-P7037
    IL-2 Protein, Human

    rHuIL-2; IL2; T-cell Growth Factor; TCGF; Aldesleukin

    Human E. coli
    IL-2 Protein, Human activates STAT, PI3K and MAPK pathways. IL-2 Protein, Human increases NK-cell cytolytic activity as a T-cell growth factor. IL-2 Protein, Human regulates the proliferation of activated B-cells and regulatory T-cells. IL-2 Protein, Human is the recombinant human-derived IL-2 Protein, expressed by E. coli.
  • HY-P7080
    IL-4 Protein, Mouse (CHO)

    rMuIL-4; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra

    Mouse CHO
    IL-4 Protein, Mouse (CHO) is a species-specific cytokine which promotes the proliferation, differentiation and cell-surface protein modulation of B lymphocytes.
  • HY-P7029A
    IL-1RA/IL-1RN Protein, Human (HEK293)

    rHuIL-1RA; IL-1RN; IRAP

    Human HEK293
    IL-1RA/IL-1RN Protein, Human (HEK293) is a member of the IL-1 family that binds to IL-1 receptors.
  • HY-P7063
    IL-6 Protein, Mouse

    rMuIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2

    Mouse E. coli
    IL-6 Protein is a multifunctional cytokine secreted by both immune and non-immune cells, and belongs to the interleukin family. IL-6 Protein plays a key role in immune responses, inflammatory reactions and other processes. IL-6 Protein, Mouse is a recombinant IL-6 protein expressed by E. coli without a tag.
  • HY-P7074A
    IL-10 Protein, Mouse (CHO)

    rMuIL-10; CSIF

    Mouse CHO
    IL-10 Protein, Mouse (CHO) is a potent CHO cell derived anti-inflammatory cytokine results in increased immune-mediated demyelination in mice infected with a neurotropic coronavirus.
  • HY-P70750G
    GMP IL-4 Protein, Human (HEK293)

    Interleukin-4; IL-4; B-Cell Stimulatory Factor 1; BSF-1; Binetrakin; Lymphocyte Stimulatory Factor 1; Pitrakinra; IL4

    Human HEK293
    GMP IL-4 Protein, Human (HEK293) is a recombinant GMP-grade protein produced by HEK293 cells with C-His tag. IL-4 is an anti-inflammatory cytokine acting as a pleiotropic regulator of numerous immune and inflammatory processes.
  • HY-P70776G
    GMP IL-15 Protein, Human

    Interleukin-15; IL-15; IL15

    Human E. coli
    The IL-15 protein is a cytokine that plays a key role in inflammatory and protective immune responses by regulating innate and adaptive immune cells. It stimulates the proliferation of natural killer cells, T cells and B cells, and promotes the secretion of cytokines. GMP IL-15 Protein, Human is the recombinant human-derived IL-15 protein, expressed by E. coli , with tag free.
  • HY-P70755G
    GMP IL-7 Protein, Human (HEK293, His)

    Interleukin-7; IL-7; IL7

    Human HEK293
    IL-7 protein is an important hematopoietic cytokine that is essential for the development, expansion and survival of T cells and B cells, regulating mature lymphocyte populations and maintaining lymphatic homeostasis. IL-7 interacts with IL7RA and CSF2RG subunits, activates kinases, including JAK1 or JAK3, and initiates signaling cascades, such as the PI3K/Akt/mTOR or JAK-STAT5 pathway. GMP IL-7 Protein, Human (HEK293, His) is the recombinant human-derived IL-7 protein, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P70758
    IL-2 Protein, Human (HEK293, His)

    Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin; IL2

    Human HEK293
    IL-2 protein is mainly produced by activated CD4-positive helper T cells and plays an important role in immune response and tolerance. Binding to IL-2R induces downstream signaling through JAK1 and JAK3 phosphorylation, thereby activating various pathways, including STAT, PI3K, and MAPK. IL-2 Protein, Human (HEK293, His) is the recombinant human-derived IL-2 protein, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P7042
    IL-4 Protein, Human (CHO)

    rHuIL-4; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra

    Human CHO
    IL-4 Protein, Human (CHO) is a CHO cell derived, potent lymphoid cell growth factor, which stimulates the growth and survivability of B-cells and T-cells.
  • HY-P7218
    IL-33 Protein, Mouse

    rMuIL-33; Il33

    Mouse E. coli
    IL-33 Protein, Mouse is a tissue-derived nuclear cytokine from the IL-1 family abundantly expressed in endothelial cells, epithelial cells and fibroblast-like cells, both during homeostasis and inflammation.
  • HY-P7044
    IL-6 Protein, Human

    rHuIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2

    Human E. coli
    IL-6 protein is a multifunctional cytokine that plays multiple biological functions in immunity, tissue regeneration, and metabolism. After binding to IL6R, the resulting complex binds to the signaling subunit IL6ST/gp130, triggering the intracellular IL6 signaling pathway. IL-6 Protein, Human (N-His) is the recombinant human-derived IL-6 protein, expressed by E. coli.
  • HY-P7028
    IL-1 beta Protein, Human

    rHuIL-1β; Catabolin; IL1F2; IL-1 beta; IL1B

    Human E. coli
    IL-1 beta is a potent proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta plays a key role in inflammation and immunologic reactions. IL-1 beta is produced as inactive pro-IL-1β (encoded by pro-Il-1b) in response to inflammatory stimuli. IL-1 beta Protein, Human consists of 153 amino acids (A117-S269) and is expressed in E. coli.
  • HY-P7037A
    IL-2 Protein, Human (CHO)

    rHuIL-2; IL2; T-cell Growth Factor; TCGF; Aldesleukin

    Human CHO
    IL-2 Protein, Human (CHO) is a CHO cell derived adjunctive immunotherapeutic agent to treat tuberculosis (TB).
  • HY-P70445
    IL-4 Protein, Human

    Interleukin-4; IL-4; B-Cell Stimulatory Factor 1; BSF-1; Binetrakin; Lymphocyte Stimulatory Factor 1; Pitrakinra; IL4

    Human E. coli
    IL-4 Protein is an endogenous agonist of IL-4 receptor (IL-4R), which works through the JAK1/JAK3-STAT6 signaling pathway. It can cooperate with SCF to promote the proliferation of human intestinal mast cells (ED50=100 pg/mL) and enhance the release of mediators such as histamine mediated by IgE receptor. IL-4 Protein can inhibit the production of IL-8 by human monocytes and regulate the secretion of endothelial cell factors. It is mainly used for IL-4R targeted therapy research of tumors (such as malignant pleural mesothelioma) and allergic diseases. IL-4 Protein, Human is a recombinant protein of human IL-4, expressed by E. coli, with tag free.
  • HY-P71963
    IL-17RA Protein, Human (HEK293, hFc)

    CANDF5; CD217; CD217 antigen; CDw217; CTLA8; HIL 17R; hIL17R; I17RA_HUMAN; IL 17 receptor A; IL 17 receptor; IL 17RA; IL-17 receptor A; IL-17RA; IL17; IL17A receptor; IL17R; IL17RA; IMD51; Interleukin 17 receptor A; Interleukin-17 receptor A; MGC10262

    Human HEK293
    IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F. IL-17RA Protein, Human (HEK 293, hFc) is produced in HEK293 cells with a C-Terminal hFc-tag.
  • HY-P7073
    IL-1 beta Protein, Mouse

    rMuIL-1β; Catabolin; IL1F2; IL-1 beta; IL1B

    Mouse E. coli
    IL-1 beta is a potent proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta plays a key role in inflammation and immunologic reactions. IL-1 beta Protein, Mouse consists of 152 amino acids (V118-S269) and is expressed in E. coli.
  • HY-P7081A
    IL-5 Protein, Mouse (CHO)

    rMuIL-5; EDF; BCDFII; TRF

    Mouse CHO
    IL-5 Protein, Mouse (CHO) is a CHO cell derived hematopoietic growth factor expressed in Th2, mast cells and eosinophils.
  • HY-P7036
    IL-17A Protein, Human

    rHuIL-17; IL-17A; Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8

    Human E. coli
    IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Human is a recombinant human IL-17A protein and is expressed in E. coli. It consists of 137 amino acids (I19-A155).
Cat. No. Product Name Effect Purity