1. One-stop Drug Screening
  2. Screening Libraries
  3. Surface Plasmon Resonance (SPR) Assay Service

Surface Plasmon Resonance (SPR) Assay Service

Surface Plasmon Resonance (SPR) is a biosensing analysis technology that utilizes the resonance between the extinction wave and the plasma wave of light in different media to construct a biosensing platform for detecting biomolecular interactions. It is used to detect the interaction between ligands and analytes on a biosensor chip.

Flowcell containing
sample matrix
Functionalized gold
sensor surface
Light Prism Detector Substrate Reflected light Reflectivity Curve Sensorgram Angle (deg.) Time
SPR schematic diagram
Service Advantages

A professional pre-sales and after-sales technical team.

Advanced equipments.

Real-time, information-rich interaction analysis data

Detection Process
Coupled ligand Sample injection Chip regeneration Data analysis

Service Types

MedChemExpress employs the Biacore 8K, Biacore 1K, and Biacore T200 instruments for affinity analysis, which can be used for the study of interactions such as antigen-antibody, protein-protein, antibody-receptor, nucleic acid-protein, and protein-small molecule compounds. Additionally, MedChemExpress provides customized diversity services for customers.

Service Items Service Standard Service Period Deliverable Note
Antigen-antibody
detection
Antibody requirement: 50 μg 2-3 weeks
after receiving
the sample
Project
Report
If the sample solution contains NaN3, imidazole, sucrose, DTT and other substances, it should be informed in advance; If amino coupling is used for detection, protein buffer should not contain primary amino components, such as Tris buffer.
Antigen requirement: 50 μg
Protein-protein
detection
Protein requirement: 50 μg
Antibody-receptor
detection
Antibody requirement: 50 μg
Receptor requirement: 50 μg
Nucleic acid-protein
detection
Nucleic acid requirement: 5 OD
Protein requirement: 50 μg
Protein-small molecule
compound detection
Protein requirement: 50 μg
Small molecule compound
requirement: 200 μg
Platform Introduction

Biacore systems are versatile and highly sensitive Surface Plasmon Resonance (SPR) systems that provide various high-quality molecular interaction data. It has comprehensive characterization and similarity analysis capabilities, supporting kinetic, affinity, and specificity analysis.

Service Consultation

The SPR testing service needs to be evaluated to determine the corresponding scheme and price. For further information about service price or technical details, please send an email to sales@MedChemExpress.com or contact the sales staff of MedChemExpress directly.

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Surface Plasmon Resonance (SPR) Assay Service

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