2. Signaling Pathways
  3. Vitamin D Related/Nuclear Receptor
  4. Constitutive Androstane Receptor

Constitutive Androstane Receptor

CAR; NR1I3

 

Constitutive Androstane Receptor Related Products (3):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-110249
    CINPA1
    		99.90%
    CINPA1 is a potent and specific inhibitor of constitutive androstane receptor (CAR) that does not activate pregnane X receptor (PXR). CINPA1 reduces CAR-mediated transcription with an IC50 of ~70 nM. CINPA1 can be used as a molecular tool for understanding CAR function.
    CINPA1
  • HY-111634
    Epsilon-momfluorothrin
    		99.76%
    Epsilon-momfluorothrin is a type I synthetic pyrethroid insecticide, activates constitutive androstane receptor (CAR), and induces hepatocellular tumors in rats.
    Epsilon-momfluorothrin
  • HY-110134
    S07662
    		Inhibitor
    S07662 is a human constitutive androstane receptor (hCAR) inhibitor with an IC50 of 0.7 μM. S07662 recruits the corepressor NCoR in cell-based assays and attenuate the expression of CYP2B6 mRNA in human primary hepatocytes induced by phenytoin (HY-B0448) and CITCO (HY-103244).
    S07662