2. Signaling Pathways
  3. Others
  4. Others

Others

 
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-108470
    Ro5-3335
    		99.52%
    Ro5-3335, a benzodiazepine, acts as an inhibitor of core binding factor (CBF) leukemia. Ro5-3335 is a RUNX1-CBFβ interaction inhibitor that represses RUNX1/CBFB-dependent transactivation.
    Ro5-3335
  • HY-154919
    DC-Y13-27
    		99.52%
    DC-Y13-27, a derivative of DC-Y13, is a YTHDF2 inhibitor (KD: 37.9 μM). DC-Y13-27 enhances tumor responses to radiotherapy and immunotherapy.
    DC-Y13-27
  • HY-11101
    Alendronate sodium hydrate
    		99.6%
    Alendronate (sodium hydrate) is a farnesyl diphosphate synthase inhibitor with IC50 of 460 nM.
    Alendronate sodium hydrate
  • HY-N3025
    Zinc sulfate heptahydrate
    		99.8%
    Zinc sulfate heptahydrate is a hydrate that is the heptahydrate form of zinc sulfate. Zinc sulfate heptahydrate is a dietary supplement used for zinc deficiency and to prevent the condition in those at high risk.
    Zinc sulfate heptahydrate
  • HY-120821
    Endosidin-2
    		Modulator 99.17%
    Endosidin2 (ES2) is an inhibitor of EXO70, and binds to the exocyst component of 70 kDa (EXO70) subunit of the exocyst complex with a Kd of 253 μM. Endosidin2 inhibits exocytosis and endosomal recycling in both plant and human cells and enhances plant vacuolar trafficking. Endosidin2 is a valuable new tool for the study of exocytosis.
    Endosidin-2
  • HY-102013
    Omilancor
    		98.44%
    BT-11 is an orally available LANCL2 binding compound for treating inflammatory bowel disease.
    Omilancor
  • HY-168000
    TREX1-IN-2
    TREX1-IN-2 (Compound 15B) is an inhibitor of TREX1 with an IC50 vaule of < 1.00 μM against Human TREX1. TREX1-IN-2 exhibits anticancer activity in vivo.
    TREX1-IN-2
  • HY-164710
    Biotinylated leptomycin B
    		99.32%
    Biotinylated leptomycin B is a compound used to quantify nuclear export protein 1 (XPO1) occupancy and is used to study the interaction of SINE compounds with XPO1 and the response of cancer cells to related compounds.
    Biotinylated leptomycin B
  • HY-146064
    OPN expression inhibitor 1
    		Inhibitor
    OPN expression inhibitor 1 (Compound 11) is an osteopontin (OPN) expression inhibitor. OPN expression inhibitor 1 can be used for breast cancer research.
    OPN expression inhibitor 1
  • HY-114231B
    Exaluren disulfate
    		≥98.0%
    Exaluren (ELX-02) disulfate is an investigational, advanced synthetic eukaryotic ribosome selective glycoside (ERSG). Exaluren disulfate is being developed as a therapy for genetic diseases caused by nonsense mutations.
    Exaluren disulfate
  • HY-108467
    GGsTop
    		Inhibitor 99.35%
    GGsTop (Nahlsgen) is a potent, non-toxic, highly selective and irreversible γ-GGT inhibitor, with a Ki of 170 μM for Human GGT. GGsTop shows a pKa of 9.71, also exhibits Kons of 150 and 51 M-1 s-1 against E.coli GGT and human GGT, respectively. GGsTop protects hepatic ischemia-reperfusion injury in rat model.
    GGsTop
  • HY-139566
    Abrucomstat
    Abrucomstat (3-Nitroxypropanol) is an orally active methyl coenzyme M reductase inhibitor. Abrucomstat decreases ruminal methanogenesis.
    Abrucomstat
  • HY-18630A
    Ro 48-8071 fumarate
    		Inhibitor 99.42%
    Ro 48-8071 fumarate is an inhibitor of OSC (Oxidosqualene cyclase) with IC50 of appr 6.5 nM.
    Ro 48-8071 fumarate
  • HY-B0404A
    Benserazide hydrochloride
    		Inhibitor 99.87%
    Benserazide hydrochloride (Serazide) is commonly used in Parkinson's disease and is an inhibitor of peripheral aromatic L-amino acid decarboxylase (AADC).
    Benserazide hydrochloride
  • HY-110150
    UNC3230
    		99.78%
    UNC3230 is a potent, selective and ATP-competitive PIP5K1C inhibitor with an IC50 of ~41 nM. UNC3230 also inhibits PIP4K2C and does not inhibit any of the other lipid kinases that regulate phosphoinositide levels. UNC3230 has antinociceptive and anticancer effects.
    UNC3230
  • HY-18681
    Voxelotor
    		Inhibitor 99.99%
    Voxelotor (GBT 440) is a potent inhibitor of haemoglobin S (HbS) polymerization. Voxelotor has the potential for sickle cell disease (SCD) treatment.
    Voxelotor
  • HY-13746B
    Sardomozide dihydrochloride
    		Inhibitor 99.76%
    Sardomozide dihydrochloride is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM.
    Sardomozide dihydrochloride
  • HY-12837
    EN460
    		Inhibitor 99.73%
    EN460 is a selective endoplasmic reticulum oxidation 1 (ERO1) inhibitor. EN460 (IC50 of 1.9 μM) interacts selectively with the reduced, active form of ERO1α and prevents its reoxidation.
    EN460
  • HY-100486
    BTTAA
    		99.68%
    BTTAA is a Cu(I)-stabilizing ligand, whch performs potently with ubiquitin Glu18AzF.
    BTTAA
  • HY-101464
    ML329
    		Inhibitor ≥98.0%
    ML329 is a micropthalmia-associated transcription factor (MITF) inhibitor, which inhibits TRPM-1 promoter activity with an IC50 of 1.2 μM.
    ML329
Cat. No. Product Name / Synonyms Application Reactivity