2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. CSF & Receptors

CSF & Receptors

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Colony-stimulating factors (CSFs), originally defined as haematopoietic cell growth factors, are the master regulators of granulocyte and macrophage populations. There are four distinct types of CSF: granulocyte-macrophage colony-stimulating factor (GM-CSF), granulocyte colony-stimulating factor (G-CSF), macrophage colony-stimulating factor (M-CSF) and multipotential colony-stimulating factor (multi-CSF, most commonly termed IL-3). CSFs stimulate the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.

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Cat. No. Product Name / Synonyms Species Source
  • HY-P7085
    M-CSF Protein, Mouse

    rMuM-CSF; CSF-1; MGI-IM

    		Mouse E. coli
    The M-CSF protein is a key orchestrator in regulating the survival, proliferation, and differentiation of hematopoietic precursor cells, particularly mononuclear phagocytes, including macrophages and monocytes. It actively promotes the release of pro-inflammatory chemokines, thereby playing a key role in innate immunity and inflammatory processes. M-CSF Protein, Mouse is the recombinant mouse-derived M-CSF protein, expressed by E. coli.
  • HY-P7361
    GM-CSF Protein, Mouse

    rMuGM-CSF; CSF-2; GM-CSF

    		Mouse E. coli
    GM-CSF Protein is a hematopoietic growth factor and immunomodulator. By binding to specific receptors on the surface of target cells, GM-CSF Protein activates intracellular signaling pathways to regulate cell proliferation, differentiation, maturation, and function. GM-CSF Protein plays an important role in the hematopoietic process and the immune system. GM-CSF Protein, Mouse is a recombinant GM-CSF Protein expressed by E. coli without a tag.
  • HY-P7016
    GM-CSF Protein, Human (CHO)

    rHuGM-CSF; CSF-2; MGI-1GM; Pluripoietin-alpha; Molgramostin; Sargramostim

    		Human CHO
    GM-CSF Protein is a hematopoietic growth factor and immunomodulator. By binding to specific receptors on the surface of target cells, GM-CSF Protein activates intracellular signaling pathways to regulate cell proliferation, differentiation, maturation, and function. GM-CSF Protein plays an important role in the hematopoietic process and the immune system. GM-CSF Protein, Human (CHO) is a recombinant GM-CSF Protein expressed by CHO without a tag.
  • HY-P7085A
    M-CSF Protein, Mouse (CHO)

    rMuM-CSF; CSF-1; MGI-IM

    		Mouse CHO
    M-CSF Protein, Mouse (CHO) is a pro-inflammatory cytokine, binds to its receptor CSF1R, and is involved in the development and proliferation of cells of the monocyte/macrophage lineage and participates in the induction of osteoclasts which are important in the destruction of bone and cartilage and in the periarticular osteoporotic changes.
  • HY-P7062
    IL-3 Protein, Mouse

    rMuIL-3; Hematopoietic growth factor; Mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor

    		Mouse E. coli
    IL-3 Protein, Mouse functions via specific cell surface receptors to stimulate the proliferation, differentiation and survival of haematopoietic cell lines.
  • HY-P7050
    M-CSF Protein, Human

    rHuM-CSF; CSF-1; MGI-IM

    		Human E. coli
    M-CSF (CSF-1) protein is a homodimeric hematopoietic growth factor and proinflammatory cytokine, belonging to the colony stimulating factor. M-CSF can act specifically on the monocyte-macrophage lineage, drive monocyte proliferation and differentiation into macrophages/osteoclasts, and induce M1 macrophages to enhance ADCC anti-tumor activity and M2 macrophages to promote VEGF angiogenesis. M-CSF Protein, Human is a recombinant human M-CSF protein expressed in E. coli with tag-free.
  • HY-P7016A
    GM-CSF Protein, Human

    rHuGM-CSF; CSF-2; MGI-1GM; Pluripoietin-alpha; Molgramostin; Sargramostim

    		Human E. coli
    GM-CSF Protein is a hematopoietic growth factor and immunomodulator. By binding to specific receptors on the surface of target cells, GM-CSF Protein activates intracellular signaling pathways to regulate cell proliferation, differentiation, maturation, and function. GM-CSF Protein plays an important role in the hematopoietic process and the immune system. GM-CSF Protein, Human is a recombinant GM-CSF Protein expressed by E. coli without a tag.
  • HY-P70567G
    GMP GM-CSF Protein, Human (HEK293, His)

    Granulocyte-macrophage colony-stimulating factor; Colony-stimulating factor; CSF; Molgramostin and Sargramostim

    		Human HEK293
    The GM-CSF protein functions as a key cytokine that promotes the growth and differentiation of hematopoietic precursor cells of different lineages, such as granulocytes, macrophages, eosinophils, and erythrocytes. In its monomeric form, GM-CSF acts as a signaling molecule, orchestrating complex receptor assemblies. GMP GM-CSF Protein, Human (HEK293, His) is the recombinant human-derived GM-CSF protein, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P7050A
    M-CSF Protein, Human (CHO)

    rHuM-CSF; CSF-1; MGI-IM

    		Human CHO
    M-CSF (CSF-1) protein is a homodimeric hematopoietic growth factor and proinflammatory cytokine, belonging to the colony stimulating factor. M-CSF can act specifically on the monocyte-macrophage lineage, drive monocyte proliferation and differentiation into macrophages/osteoclasts, and induce M1 macrophages to enhance ADCC anti-tumor activity and M2 macrophages to promote VEGF angiogenesis. M-CSF Protein, Human (CHO) is a recombinant human M-CSF protein expressed in CHO cells with tag-free.
  • HY-P70553
    M-CSF Protein, Mouse (HEK293)

    Macrophage colony-stimulating factor 1; CSF-1; MCSF; Csf1; Csfm

    		Mouse HEK293
    M-CSF Protein, Mouse (HEK293) is a pro-inflammatory cytokine which binds to its receptor CSF1R, and is involved in the development and proliferation of cells of the monocyte/macrophage lineage and participates in the induction of osteoclasts.
  • HY-P70422
    G-CSF Protein, Human

    Granulocyte Colony-Stimulating Factor; G-CSF; Pluripoietin; Filgrastim; Lenograstim; CSF3; C17orf33; GCSF

    		Human E. coli
    Granulocyte colony-stimulating factor (G-CSF) is a glycoprotein secreted by the cells of the immune system, fibroblasts and endothelium, which acts as a hematopoietic and endothelial precursor cells cytokine. G-CSF stimulates maturation of progenitor cells in the bone marrow into differentiated granulocytes, macrophages and the T cells. G-CSF also shows to convey neuroprotection to central neurons upon increases in phosphorylation of PI3K/Akt pathway and regulates epithelial to mesenchymal transition in cancer. G-CSF Protein (Human) is a recombinant protein with tag free that consists of 200 or 204 amino acids, which is expressed in E. coli.
  • HY-P70576
    IL-3 Protein, Human (His)

    Interleukin-3; IL-3; Hematopoietic Growth Factor; Mast Cell Growth Factor; MCGF; Multipotential Colony-Stimulating Factor; P-Cell-Stimulating Factor; IL3

    		Human E. coli
    IL-3 protein is mainly secreted by T lymphocytes, mast cells and osteoblasts and is critical for the generation and differentiation of hematopoietic progenitor cells. It stimulates mature basophils, eosinophils and monocytes, promoting functional activation. IL-3 Protein, Human (His) is the recombinant human-derived IL-3 protein, expressed by E. coli , with N-6*His labeled tag.
  • HY-P70685
    IL-3 Protein, Mouse (HEK293, His)

    Interleukin-3; IL-3; Hematopoietic growth factor; Multipotential colony-stimulating factor; P-cell-stimulating factor; Il3; Il-3; Mast cell growth factor; MCGF

    		Mouse HEK293
    IL-3 Protein, Mouse (HEK293, His) is a multilineage hematopoietic cytokine with promising effects on platelet and neutrophil counts and special usefulness in patients with secondary hematopoietic failure.
  • HY-P70623
    GM-CSF Protein, Mouse (HEK293, His)

    Granulocyte-Macrophage Colony-Stimulating Factor; GM-CSF; Colony-Stimulating Factor; CSF; Molgramostin; Sargramostim; CSF2; GMCSF

    		Mouse HEK293
    The GM-CSF protein acts as a potent cytokine that coordinates the growth and differentiation of hematopoietic precursor cells of different lineages, including granulocytes, macrophages, eosinophils, and erythrocytes. Structurally, GM-CSF exists as a monomer and its signaling is mediated through a dodecamer complex. GM-CSF Protein, Mouse (HEK293, His) is the recombinant mouse-derived GM-CSF protein, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P7015A
    G-CSF Protein, Human (CHO)

    rHuG-CSF; CSF-3; MGI-1G; Pluripoietin; Molgramostin; Sargramostim

    		Human CHO
    G-CSF Protein, Human (CHO) is a polypeptide growth factor that regulates the production of neutrophilic granulocytes.
  • HY-P70765
    IL-3 Protein, Human (HEK293, His)

    Interleukin-3; IL-3; Hematopoietic Growth Factor; Mast Cell Growth Factor; MCGF; Multipotential Colony-Stimulating Factor; P-Cell-Stimulating Factor; IL3

    		Human HEK293
    IL-3 Protein, Human (HEK293, His) is a multipotent hematopoietic growth factor that can control blood formation. IL-3 Protein, Human (HEK293, His) is a recombinant human interleukin-3 (rhIL-3) expressed in HEK 293 cells with a His tag. rhIL-3 is also a weak inflammatory mediator. rhIL-3 can be used to improve states of hematopoietic failure.
  • HY-P7040A
    IL-3 Protein, Human (CHO)

    rHuIL-3; Hematopoietic growth factor; Mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor

    		Human CHO
    IL-3 Protein, Human (CHO) is a multilineage hematopoietic cytokine with promising effects on platelet and neutrophil counts and special usefulness in patients with secondary hematopoietic failure.
  • HY-P73207
    IL-3 Protein, Mouse (HEK293)

    Interleukin-3; IL-3; MCGF

    		Mouse HEK293
    IL-3 protein is secreted by T lymphocytes, mast cells and osteoblasts. It plays an important regulatory role in hematopoietic progenitor cells and stimulates mature basophils, eosinophils and monocytes. In addition to hematopoiesis, it supports neuronal cell proliferation, survival, and bone homeostasis by inhibiting osteoclast differentiation. IL-3 Protein, Mouse (HEK293) is the recombinant mouse-derived IL-3 protein, expressed by HEK293 , with tag free.
  • HY-P73827
    M-CSF Protein, Human (HEK293, His)

    Macrophage Colony-Stimulating Factor 1; CSF-1; M-CSF; Lanimostim

    		Human HEK293
    The M-CSF protein is an important cytokine that modulates hematopoietic precursor cells, especially mononuclear phagocytes, affecting innate immunity and inflammation through the release of proinflammatory chemokines. It is essential for osteoclast proliferation and regulates bone resorption, bone development and fertility. M-CSF Protein, Human (HEK293, His) is the recombinant human-derived M-CSF protein, expressed by HEK293 , with C-10*His labeled tag.
  • HY-P70567
    GM-CSF Protein, Human (HEK293, His)

    Granulocyte-macrophage colony-stimulating factor; Colony-stimulating factor; CSF; Molgramostin and Sargramostim.

    		Human HEK293
    The GM-CSF protein functions as a key cytokine that promotes the growth and differentiation of hematopoietic precursor cells of different lineages, such as granulocytes, macrophages, eosinophils, and erythrocytes. In its monomeric form, GM-CSF acts as a signaling molecule, orchestrating complex receptor assemblies. GM-CSF Protein, Human (HEK293, His) is the recombinant human-derived GM-CSF protein, expressed by HEK293 , with C-6*His labeled tag.
Cat. No. Product Name Effect Purity