2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. VEGF & VEGFR

VEGF & VEGFR

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Vascular endothelial growth factors (VEGFs) are a family of secreted polypeptides that are crucial to the normal development and maintenance of the vascular and lymphatic systems. VEGF stimulates endothelial cells to degrade extracellular matrix, proliferate, migrate, and form tubes, and acts as an endothelial cell survival factor. VEGF also increases vascular permeability. So far, VEGF family includes VEGF-A, VEGF-B, VEGF-C, VEGF-D (FIGF), VEGF-Es, and placenta growth factor (PlGF). VEGFs have been found in all vertebrate species so far examined and are highly conserved between species. The biological functions of the VEGFs are mediated by VEGFRs (VEGFR1, VEGFR2, and VEGFR3), a family of cognate protein tyrosine kinase receptors, and two non-protein kinase co-receptors known as neuropilins (Neuropilin-1 and Neuropilin-2).

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Cat. No. Product Name / Synonyms Species Source
  • HY-P7110A
    VEGF165 Protein, Human (HEK293)

    VEGF-AA; rHuVEGF165; VPF; Folliculostellate cell-derived growth factor; Glioma-derived endothelial cell mitogen

    		Human HEK293
    VEGF165 Protein, Human is a Vascular Endothelial Growth Factor A (VEGF-A) isoform. VEGF165 Protein is the growth factor that affects the angiogenesis, vasculogenesis and endothelial cell growth. VEGF165 Protein can binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin, and affects the motor neuron signaling pathway. VEGF165 Protein, Human (HEK293) is a human-derived VEGF165 Protein that can be expressed by HEK293.
  • HY-P7313
    VEGF-C Protein, Human (116a.a, HEK293)

    rHuVEGF-C; Vascular endothelial growth factor C; Flt4-L; VRP

    		Human HEK293
    VEGF-C Protein, Human (116a.a, HEK293) functions in lymphangiogenesis, where it acts on lymphatic endothelial cells (LECs) primarily via its receptor VEGFR-3 promoting survival, growth and migration.
  • HY-P7311
    VEGF164 Protein, Rat (CHO)

    rRtVEGF164; VEGF-AA; VPF

    		Rat CHO
    VEGF164 Protein, Rat (CHO) is a potent mediator of angiogenesis and binds the semaphorin receptor, neuropilin1.
  • HY-P73529
    VEGF-C Protein, Human (125a.a, HEK293, His)

    Flt4-L; vascular endothelial growth factor C; VEGFC; VRP

    		Human HEK293
    The VEGF-C protein is a potent growth factor in angiogenesis and endothelial cell growth, stimulating cell proliferation and migration while affecting vascular permeability. It plays a critical role in embryonic vein and lymphangiogenesis and maintains adult differentiated lymphatic endothelium. VEGF-C Protein, Human (125a.a, HEK293, His) is the recombinant human-derived VEGF-C protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P7312
    VEGF164 Protein, Mouse

    VEGF-AA; rMuVEGF164; VPF

    		Mouse E. coli
    VEGF164 Protein, Mouse is a potent mediator of angiogenesis and binds the semaphorin receptor, neuropilin1.
  • HY-P78229
    VEGF165 Protein, Human (Biotinylated, HEK293, His-Avi)

    VEGF-AA; VEGF; MVCD1; VAS; VEGFMGC70609; VPF; RP1-261G23.1; MGC70609

    		Human HEK293
    VEGF165 Protein is a subtype of Vascular Endothelial Growth Factor A (VEGF-A). VEGF-A is a key member of the VEGF family of cytokines that can promote neovascularization and increase vascular permeability. VEGF165 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived VEGF165 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of VEGF165 Protein, Human (Biotinylated, HEK293, His-Avi) is 165 a.a., with molecular weight of 28-32 kDa.
  • HY-P70552
    VEGFR-2 Protein, Human (HEK293, His)

    Vascular endothelial growth factor receptor 2; KDR; VEGFR-2; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; Protein-tyrosine kinase receptor flk-1; VEGFR2; VEGF R2

    		Human HEK293
    VEGFR-2 is a tyrosine-protein kinase of the cell surface receptors of VEGFA, VEGFC, and VEGFD that mediates activation of the MAPK1/ERK2, MAPK3/ERK1, and MAP kinase signaling pathways, as well as the AKT1 signaling pathway. VEGFR-2 can promote the proliferation, survival, migration and differentiation of endothelial cells. Overexpression of VEGFR-2 is associated with the development of tumors. VEGFR-2 Protein, Human (HEK293, His) is the recombinant human-derived VEGFR-2 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P72775
    VEGF120 Protein, Mouse

    VEGF-AA; Vascular endothelial growth factor A; VPF; VEGFA

    		Mouse E. coli
    VEGF-A Protein is a key member of the VEGF family of cytokines.VEGF-A participates in angiogenesis, vasculogenesis, and endothelial cell growth, inducing endothelial cell proliferation, promoting cell migration, inhibiting cell apoptosis, and inducing vascular permeability.VEGF-A stimulates endothelial cell mitogenesis and cell migration.VEGF120 Protein, Mouse is the recombinant mouse-derived VEGF120 protein, expressed by E.coli , with tag free.
  • HY-P73471
    VEGF121 Protein, Human (HEK293)

    VEGF-AA; MVCD1; VAS; Vascular endothelial growth factor A; VEGF; VPF

    		Human HEK293
    VEGF121 Protein is a subtype of Vascular Endothelial Growth Factor A (VEGF-A). VEGF-A is a key member of the VEGF family of cytokines that can promote neovascularization and increase vascular permeability. VEGF121 Protein, Human (HEK293) is the recombinant human-derived VEGF121 protein, expressed by HEK293 , with tag free. The total length of VEGF121 Protein, Human (HEK293) is 147 a.a., with molecular weight of ~19.9 & 17.0 kDa, respectively.
  • HY-P70635
    VEGFR-2 Protein, Human (745a.a, HEK293, Fc)

    Vascular endothelial growth factor receptor 2; KDR; VEGFR-2; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; Protein-tyrosine kinase receptor flk-1; VEGFR2; VEGF R2

    		Human HEK293
    VEGFR-2 protein is a tyrosine protein kinase receptor for VEGFA, VEGFC and VEGFD and is critical in angiogenesis, blood vessel development and embryonic hematopoiesis. It promotes endothelial cell function and actin cytoskeletal reorganization. VEGFR-2 Protein, Human (745a.a, HEK293, Fc) is the recombinant human-derived VEGFR-2 protein, expressed by HEK293 , with C-hFc labeled tag.
  • HY-P70792
    PLGF Protein, Mouse (HEK293, His)

    Placenta growth factor; PlGF; Plgf; D12S1900; PGFL; PLGF; PlGF-2; SHGC-10760

    		Mouse HEK293
    PLGF protein is an important growth factor in angiogenesis and endothelial cell growth, stimulating cell proliferation and migration by binding to the FLT1/VEGFR-1 receptor.PLGF plays a crucial role in angiogenesis and also contributes to tumor growth, highlighting its involvement in pathological angiogenesis.PLGF Protein, Mouse (HEK293, His) is the recombinant mouse-derived PLGF protein, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P73065
    VEGFR-1 Protein, Human (328a.a, HEK293, His)

    Vascular endothelial growth factor receptor 1; FLT; FLT1; FRT; VEGFR-1

    		Human HEK293
    The VEGFR-1 protein is a tyrosine protein kinase that acts as a cell surface receptor for VEGFA, VEGFB, and PGF. It plays a crucial role in embryonic vasculature development, regulation of angiogenesis, cell survival, migration, macrophage function, chemotaxis, and cancer cell invasion. VEGFR-1 Protein, Human (328a.a, HEK293, His) is the recombinant human-derived VEGFR-1 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P73474
    VEGF-D Protein, Mouse (HEK293, Fc)

    Vascular endothelial growth factor D; VEGF-D; FIGF

    		Mouse HEK293
    VEGF-D Protein, a versatile growth factor, orchestrates angiogenesis, lymphangiogenesis, and endothelial cell growth. It stimulates proliferation, migration, and influences vessel permeability. VEGF-D binds VEGFR-3, triggering crucial signaling for vascular development. Structurally, VEGF-D is a non-covalent homodimer, emphasizing its intricate role in vascular processes. VEGF-D Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived VEGF-D protein, expressed by HEK293 , with N-hFc labeled tag.
  • HY-P73477
    VEGFR-2 Protein, Human (208a.a, HEK293, Fc)

    Vascular endothelial growth factor receptor 2; KDR; VEGFR-2; FLK-1; CD309

    		Human HEK293
    VEGFR-2 protein is a tyrosine protein kinase receptor for VEGFA, VEGFC and VEGFD and is critical in angiogenesis, blood vessel development and embryonic hematopoiesis. It promotes endothelial cell function and actin cytoskeletal reorganization. VEGFR-2 Protein, Human (208a.a, HEK293, Fc) is the recombinant human-derived VEGFR-2 protein, expressed by HEK293 , with C-hFc labeled tag.
  • HY-P74472
    VEGFR-2 Protein, Mouse (Biotinylated, HEK293, His)

    Vascular endothelial growth factor receptor 2; VEGFR-2; FLK-1; CD309

    		Mouse HEK293
    VEGFR-2 protein is an important tyrosine protein kinase receptor.As a cell surface receptor for VEGFA, VEGFC and VEGFD, it plays an important role in the regulation of angiogenesis, vascular development, permeability and embryonic hematopoiesis.It actively promotes endothelial cell proliferation, survival, migration, differentiation, and actin cytoskeletal reorganization.VEGFR-2 Protein, Mouse (Biotinylated, HEK293, His) is the recombinant mouse-derived VEGFR-2 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P74474
    VEGF-C Protein, Mouse/Rat (HEK293, His)

    Flt4-L; vascular endothelial growth factor C; VEGFC; VRP

    		Mouse; Rat HEK293
    VEGF-C protein stimulates cell proliferation, migration, and vascular permeability, which are critical for angiogenesis and endothelial cell dynamics. It plays a crucial role in the development of the venous and lymphatic vasculature during embryogenesis and in the maintenance of adult lymphatic endothelium. VEGF-C Protein, Mouse/Rat (HEK293, His) is the recombinant mouse, rat-derived VEGF-C protein, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P78230
    VEGFR-1 Protein, Human (Biotinylated, HEK293, His-Avi)

    FLT; FLT1; Flt-1; FRT; VEGF R1; VEGFR1

    		Human HEK293
    The VEGFR-1 protein is a tyrosine protein kinase that acts as a cell surface receptor for VEGFA, VEGFB, and PGF. It plays a crucial role in embryonic vasculature development, regulation of angiogenesis, cell survival, migration, macrophage function, chemotaxis, and cancer cell invasion. VEGFR-1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived VEGFR-1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
  • HY-P78231
    VEGFR-2 Protein, Human (Biotinylated, HEK293, His-Avi)

    CD309; KDR; VEGFR; VEGFR2; VEGFR-21; FLK1; KRD1; Ly73

    		Human HEK293
    VEGFR-2 protein is a tyrosine protein kinase receptor for VEGFA, VEGFC and VEGFD and is critical in angiogenesis, blood vessel development and embryonic hematopoiesis. It promotes endothelial cell function and actin cytoskeletal reorganization. VEGFR-2 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived VEGFR-2 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
  • HY-P78536
    VEGFR-2 Protein, Human (HEK293, mFc)

    CD309; KDR; VEGFR; VEGFR2; VEGFR-21; FLK1; KRD1; Ly73

    		Human HEK293
    VEGFR-2 protein is a tyrosine protein kinase receptor for VEGFA, VEGFC and VEGFD and is critical in angiogenesis, blood vessel development and embryonic hematopoiesis. It promotes endothelial cell function and actin cytoskeletal reorganization. VEGFR-2 Protein, Human (HEK293, mFc) is the recombinant human-derived VEGFR-2 protein, expressed by HEK293 , with C-mFc labeled tag.
  • HY-P78537
    VEGFR-1 Protein, Human (HEK293, His-Avi)

    FLT; FLT1; Flt-1; FRT; VEGF R1; VEGFR1

    		Human HEK293
    The VEGFR-1 protein is a tyrosine protein kinase that acts as a cell surface receptor for VEGFA, VEGFB, and PGF. It plays a crucial role in embryonic vasculature development, regulation of angiogenesis, cell survival, migration, macrophage function, chemotaxis, and cancer cell invasion. VEGFR-1 Protein, Human (HEK293, His-Avi) is the recombinant human-derived VEGFR-1 protein, expressed by HEK293 , with C-His, C-Avi labeled tag.
Cat. No. Product Name Effect Purity