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Results for "

pH sensitive

" in MedChemExpress (MCE) Product Catalog:

26

Inhibitors & Agonists

13

Fluorescent Dye

4

Biochemical Assay Reagents

4

Peptides

1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D1563
    CypHer 5

    		Fluorescent Dye Others
    CypHer 5 is a pH-sensitive cyanine derivative and a environmental sensitive fluorophore. CypHer 5 has a pH-sensitive maximal absorption at 644 nm and emission at 664 nm. CypHer 5 has been used as a pH sensor of lysosomal compartments .
    CypHer 5
  • HY-W133967
    Calcium alginate

    		Biochemical Assay Reagents Inflammation/Immunology
    Calcium alginate is a biopolymer that can be used for developing oral agent-delivery systems . Calcium alginate is a pH sensitive hydrogel stable in acidic media and soluble in basic media .
    Calcium alginate
  • HY-W110898
    Nile blue chloride

    		Fluorescent Dye Others
    Nile blue chloride is a highly fluorescent and photostable organic dye. Nile blue chloride and fluorescein isothiocyanate (FITC) can be used to construct a ratiometric pH sensitive probe for tracking the pH of the extracellular fluid between cancer cells in realtime. Nile Blue chloride has the potential for the research of nonlinear optics .
    Nile blue chloride
  • HY-118155
    9-Amino-6-chloro-2-methoxyacridine

    		Fluorescent Dye Others
    9-Amino-6-chloro-2-methoxyacridine is a pH sensitive fluorescent probe. 9-Amino-6-chloro-2-methoxyacridine has been frequently used to measure changes in vacuolar pH when a specific substrate crosses the tonoplast through a putative H +/solute antiport system .
    9-Amino-6-chloro-2-methoxyacridine
  • HY-145616
    Sudocetaxel

    		Microtubule/Tubulin Cancer
    Sudocetaxel is a microtubule depolymerization inhibitor for pH-sensitive docetaxel delivery.
    Sudocetaxel
  • HY-D1457
    DND-189

    		Fluorescent Dye Others
    DND-189, a low-pH fluorescent probe, is sensitive to neutral and low pH range. DND-189 can be used to measure the pH of acidic organelles .
    DND-189
  • HY-D0075
    DHPDS disodium salt

    		Fluorescent Dye Others
    DHPDS disodium salt is a pH-sensitive fluorescent dye. DHPDS disodium salt is used to measure intracellular pH (pHi) from the surface fluorescence of the isolated perfused rat liver .
    DHPDS disodium salt
  • HY-101882
    BCECF
    1 Publications Verification

    2′,7′-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein

    		 Fluorescent Dye Others
    BCECF is a pH-sensitive fluorescent dye. BCECF allows measurements in the physiological pH range 6.0–8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm.
    BCECF
  • HY-144025
    DOBAQ

    		Liposome Others
    DOBAQ, a cationic lipid, is a pH-sensitive lipid. DOBAQ can be used for liposomes applied in drug delivery .
    DOBAQ
  • HY-147104
    Fmoc-Lys(5-FITC)-OH

    		Fluorescent Dye Others
    Fmoc-Lys(5-FITC)-OH is a marker for polypeptides or proteins. FITC is a fluorescence probe for the labeling of amines. FITC is a pH- and Cu 2+-sensitive fluorescence dye .
    Fmoc-Lys(5-FITC)-OH
  • HY-D1094
    Carboxy-SNARF 1 (5/6-mixture)

    SNARF 1

    		 Fluorescent Dye Others
    Carboxy-SNARF 1 (5/6-mixture) (SNARF 1) is a fluorescent probe that is sensitive to pH. Carboxy-SNARF 1 (5/6-mixture) can be used for measurement of intracellular pH .
    Carboxy-SNARF 1 (5/6-mixture)
  • HY-D1093
    Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture)

    		Fluorescent Dye Others
    Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture) is a fluorescent probe that is sensitive to pH. Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture) can be used for measurement of intracellular pH .
    Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture)
  • HY-D1556
    DOPE-CF

    		Fluorescent Dye Others
    DOPE-CF is a pH-sensitive fluorescent membrane labelled probe with a fluorescein moiety that is a weak acid and a conjugated base that is highly fluorescent and can be attached to phospholipid ethanolamine lipids .
    DOPE-CF
  • HY-W250149
    Chlorophosphonazo III

    		Biochemical Assay Reagents Others
    Chlorophosphonazo III is a sensitive reagent for both calcium and magnesium. It is possible to determine calcium alone at pH 2.2 and calcium and magnesium at pH 7.0. Chlorophosphonazo III can also be used for the spectrophotometric determination of titanium, zirconium, thorium, and scandium, quinquevalent actinide elements, and protactinium .
    Chlorophosphonazo III
  • HY-D0023
    Pyranine
    1 Publications Verification

    HPTS; Solvent Green 7

    		 Fluorescent Dye Others
    Pyranine (HPTS; Solvent Green 7) is a pH-sensitive fluorescent indicator. Pyranine acts as a class of fluorescent chemosensor for the Cu + ion(λex=450 nm, λem=510 nm) .
    Pyranine
  • HY-W040291
    7-Hydroxy-4-methylcoumarin-3-acetic acid, SE

    		Fluorescent Dye Cancer
    7-Hydroxy-4-methylcoumarin-3-acetic acid, SE is a blue fluorophore that has pH-dependent and environment-sensitive fluorescence. It is widely used for preparing bioconjugates of blue fluorescence.
    7-Hydroxy-4-methylcoumarin-3-acetic acid, SE
  • HY-155717
    NDBM

    		Autophagy Pim Cancer
    NDBM is a probe and binds to tumor-specific Pim-1 kinase, releases strong fluorescence, and produces cytotoxicity, thus achieving cell screening and killing effects. NDBM can specifically target lysosomes and sensitively respond to pH. NDBM can be used to track the pH changes in the intracellular environment under conditions of autophagy and external stimulation .
    NDBM
  • HY-D1593
    BODIPY TMR-X alkyne

    		Fluorescent Dye Others
    BODIPY TMR-X alkyne, an orange-fluorescent dye, is an alkyne modified BODIPY TMR-X. BODIPY TMR-X alkyne can react with azides by the copper-catalyzed click reaction. BODIPY TMR-X alkyne is not sensitive to pH.
    BODIPY TMR-X alkyne
  • HY-139305
    CL4H6

    		Liposome Cancer
    CL4H6 is a pH-sensitive cationic lipid. CL4H6 is the main component of lipid nanoparticles (LNPs), which can be used to target and deliver siRNA, and induces a potent gene-silencing response .
    CL4H6
  • HY-W040144
    Bromocresol green

    		Fluorescent Dye Others
    Bromocresol green is a pH-sensitive triphenylmethane dye commonly used for the determination of protein and albumin in serum. Bromocresol green is a bio-based dye with a yellow-green to blue-green color. Bromocresol green turns yellow (λmax=435 nm, protonated form) when placed in acidic solution (e.g. pH=4.15), and turns blue in basic solution (λmax=615 nm, deprotonated form). Bromocresol green is widely used as a pH indicator in the field of biochemical analysis. In addition, Bromocresol green is also used to detect the concentration of molecules such as creatinine, and to judge the viability of cells .
    Bromocresol green
  • HY-P99681
    Labetuzumab govitecan

    IMMU 130; hMN-14-SN-38

    		 Antibody-Drug Conjugates (ADCs) Cancer
    Labetuzumab govitecan (IMMU 130) is an Anti-CEACAM5/SN-38 antibody-drug conjugate (ADC). Labetuzumab govitecan consists of the antibody Labetuzumab, SN-38, and a pH-sensitive Linker. Labetuzumab govitecan can be used for research of cancers, such as colorectal cancer .
    Labetuzumab govitecan
  • HY-15940
    5(6)-Carboxyfluorescein
    2 Publications Verification

    5(6)-FAM; 5-(and-6)-Carboxyfluorescein mixed isomers

    		 Fluorescent Dye Cancer
    5(6)-Carboxyfluorescein (5(6)-FAM) is an amine-reactive pH-sensitive green fluorescent probe. 5(6)-Carboxyfluorescein (5(6)-FAM) can be used to label proteins, peptides and nucleotides. 5(6)-Carboxyfluorescein can be used for the detection of tumour areas in vivo .
    5(6)-Carboxyfluorescein
  • HY-124473
    Naphthofluorescein

    NapHthafluorescein

    		 HIF/HIF Prolyl-Hydroxylase Cancer
    Naphthofluorescein inhibits the interaction between HIF-1 and Mint3. Naphthofluorescein suppresses Mint3-dependent HIF-1 activity and glycolysis in cancer cells and macrophages without cytotoxicity in vitro and adverse effect in vivo . Naphthofluorescein is also a fluorescent pH-sensitive probe that can be used for functional Cerenkov imaging .
    Naphthofluorescein
  • HY-147087
    YSK 05

    		Liposome Cancer
    YSK 05 is a pH-sensitive cationic lipid. YSK 05 improves the intracellular trafficking of non-viral vectors. YSK 05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK 05 overcomes the suppression of endosomal escape by PEGylation. YSK 05 effectively enhances siRNA delivery both in vitro and in vivo .
    YSK 05
  • HY-P4108
    TAT-HA2 Fusion Peptide

    		Influenza Virus Others
    TAT-HA2 Fusion Peptide is a peptide-based delivery agent that combines the pH-sensitive HA2 fusion peptide from Influenza and the cell-penetrating peptide TAT from HIV. TAT-HA2 Fusion Peptide induces the cellular uptake of macromolecules into endosomes via the TAT moiety and to respond to the acidifying lumen of endosomes to cause membrane leakage and release of macromolecules into cells via the HA2 moiety .
    TAT-HA2 Fusion Peptide
  • HY-156514
    MC-GGFG-AM-(10NH2-11F-Camptothecin)

    		Drug-Linker Conjugates for ADC Cancer
    MC-GGFG-AM-(10NH2-11F-Camptothecin) is an antibody drug conjugates (ADC). MC-GGFG-AM-(10NH2-11F-Camptothecin) binds to the anti-TROp-2 antibody sacituzumab via a hydrolysable pH-sensitive linker and has anti-tumor activity. MC-GGFG-AM-(10NH2-11F-Camptothecin) can be used for cancer research .
    MC-GGFG-AM-(10NH2-11F-Camptothecin)

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