2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. Batrachotoxin

Batrachotoxin (BTX) is a potent neurotoxin and cardiotoxin found in the skin of the Colombian poison dart frog (Phyllobates aurotaenia). Batrachotoxin is a sodium channel activator that interacts with voltage-gated sodium channels on the cell membrane, blocking the normal closure of sodium channels, causing a continuous influx of sodium ions into the cell, thereby causing a sustained depolarization of the cell.

For research use only. We do not sell to patients.

Batrachotoxin Chemical Structure

Batrachotoxin Chemical Structure

CAS No. : 23509-16-2

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Batrachotoxin Related Antibodies

Top Publications Citing Use of Products

View All Sodium Channel Isoform Specific Products:

View All Isoforms
Nav1.1 Nav1.2 Nav1.3 Nav1.4 Nav1.5 Nav1.6 Nav1.7 Nav1.8

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Batrachotoxin (BTX) is a potent neurotoxin and cardiotoxin found in the skin of the Colombian poison dart frog (Phyllobates aurotaenia). Batrachotoxin is a sodium channel activator that interacts with voltage-gated sodium channels on the cell membrane, blocking the normal closure of sodium channels, causing a continuous influx of sodium ions into the cell, thereby causing a sustained depolarization of the cell[1].

Molecular Weight

538.67

Formula

C31H42N2O6
CAS No.
SMILES

C[C@@]1(CC2)[C@]([C@@H]3O)(O4)C([C@](CC=C5[C@H](C)OC(C(C(C)=CN6)=C6C)=O)(OCCN7C)[C@]5(C7)C3)=CC[C@]1([H])C[C@]42O
Structure Classification
Initial Source

Phyllobates aurotaenia
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Batrachotoxin Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Batrachotoxin23509-16-2BTXSodium ChannelNa channelsNa+ channelsNeurotoxinheart toxinssodium channeldepolarizationactivatorInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Batrachotoxin
Cat. No.:
HY-12549
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.