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internal standard

" in MedChemExpress (MCE) Product Catalog:

50

Inhibitors & Agonists

1

Biochemical Assay Reagents

5

Peptides

14

Natural
Products

13

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-110225
    Levetiracetam-d6 (ring-d6)

    UCB L059-d6 (ring-d6)

    		 Others Others
    Levetiracetam-d6 (ring-d6) can be used as internal standard for the determination of Levetiracetam (HY-B0106) content in whole blood .
    Levetiracetam-d6 (ring-d6)
  • HY-W707056
    Latanoprost acid-d4

    		Biochemical Assay Reagents Others
    Latanoprost acid-d4 is used as the internal standard in the HPLC-MS/MS analysis to determine the level of Latanoprost acid (HY-113756A) in aqueous humor samples of eyes .
    Latanoprost acid-d4
  • HY-W004262
    Methyl nonadecanoate

    		Others Others
    Methyl nonadecanoate may be used as an internal standard to determine fatty acid methyl ester (FAME) content of biodiesel .
    Methyl nonadecanoate
  • HY-P3751
    [Tyr8] Bradykinin

    		Bradykinin Receptor ERK Cardiovascular Disease Endocrinology
    [Tyr8] Bradykinin is a B2 kinin receptor agonist. [Tyr8] Bradykinin also stimulates ERK1/2 phosphorylation. [Tyr8] Bradykinin can be used as an internal standard .
    [Tyr8] Bradykinin
  • HY-A0135
    Enflurane

    		Potassium Channel Neurological Disease
    Enflurane, a volatile anaesthetic, is a potent inhibitor of high conductance Ca 2+-activated K+ channels of Chara australis. Enflurane is an internal standard in monitoring halogenated volatile anaesthetics by headspace gas chromatography-mass spectrometry .
    Enflurane
  • HY-112552
    1,2-Distearoyl-sn-glycerol

    DSG; 1,2-Dioctadecanoyl-sn-glycerol

    		 Endogenous Metabolite Others
    1,2-Distearoyl-sn-glycerol (DSG; 1,2-Dioctadecanoyl-sn-glycerol) acts as an internal standard for Separation and identification of molecular species of 1,2-diacyl-sn-glycerol (DAG) .
    1,2-Distearoyl-sn-glycerol
  • HY-W725954
    Triheneicosanoin

    		Others Others
    Triheneicosanoin is a triacylglycerol containing heneicosanoic acid groups. Triheneicosanoin can be used as internal standard for the quantification of fatty acids in the milk samples .
    Triheneicosanoin
  • HY-113209S
    8-Iso-PGF2a-d4

    8-iso Prostaglandin F2α-d4

    		 Isotope-Labeled Compounds Metabolic Disease
    8-Iso-PGF2a-d4 (8-iso Prostaglandin F2α-d4) is an active compound. 8-Iso-PGF2a-d4 can be used the internal standard .
    8-Iso-PGF2a-d4
  • HY-B0870S
    Bensulfuron-methyl-d6

    		Isotope-Labeled Compounds Others
    Bensulfuron-methyl-d6 is a deuterated Bensulfuron-methyl (HY-B0870) (sulfonylurea pesticides). Bensulfuron-methyl-d6 can be used as an internal standard for the determination of pesticide residues by LC-MS[1].
    Bensulfuron-methyl-d6
  • HY-141632
    Sphinganine-C17

    Heptadecasphinganine

    		 Bacterial Infection Neurological Disease
    Sphinganine-C17 (Heptadecasphinganine) is a synthetic bioactive sphingolipid and an isomer of sphinganine. Sphinganine-C17 inhibits the growth of Candida glabrata and Candida albicans with a minimum bactericidal concentration (MBC) of 0.5 μg/mL for both. Sphinganine-C17 can be used as an internal standard for the chromatographic analysis of sphingosine compounds .
    Sphinganine-C17
  • HY-111095S1
    D-(-)-Lactic acid-13C

    (R)-2-Hydroxypropionic acid-13C; D-Lactic acid-13C

    		 Isotope-Labeled Compounds Others
    D-(-)-Lactic acid-13C ((R)-2-Hydroxypropionic acid-13C) is a 13C-labeled D-Lactic acid. D-(-)-Lactic acid-13C can be used as an internal standard and can also be used in studies such as metabolic tracing.
    D-(-)-Lactic acid-13C
  • HY-B0389A
    D-Glucose-13C6
    Maximum Cited Publications
    6 Publications Verification

    Glucose-13C6; D-(+)-Glucose-13C6; Dextrose-13C6

    		 Endogenous Metabolite Others Metabolic Disease
    D-Glucose- 13C6 is a stable isotope-labeled counterpart of D-glucose (HY-B0389). D-Glucose- 13C6 can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard .
    D-Glucose-13C6
  • HY-P3750
    Methionyl-Lysyl-Bradykinin

    Met-Lys-Bradykinin

    		 Bradykinin Receptor Cardiovascular Disease Endocrinology
    Methionyl-Lysyl-Bradykinin (Met-Lys-Bradykinin), a Bradykinin (HY-P0206) analogue, is a kinin .
    Methionyl-Lysyl-Bradykinin
  • HY-W004285
    Methyl undecanoate

    		Others Others
    Methyl undecanoate is an internal standard in gas-liquid chromatogram .
    Methyl undecanoate
  • HY-W004154
    2-Ethylbutyric acid

    		Others Others
    2-Ethylbutyric acid acts as an internal standard (IS) in a standard addition calibration method for the VFA analysis of faeces .
    2-Ethylbutyric acid
  • HY-W016993
    2,3,4-Trihydroxybenzoic acid

    		Others Others
    2,3,4-Trihydroxybenzoic acid is an internal standard in separation of phenolic acids by HPLC.
    2,3,4-Trihydroxybenzoic acid
  • HY-W012606
    1,5,5-Trimethylhydantoin

    TMH

    		 Others Others
    1,5,5-Trimethylhydantoin (TMH) is a non-isotopic internal standard (IS) .
    1,5,5-Trimethylhydantoin
  • HY-W004285R
    Methyl undecanoate (Standard)

    		Others Others
    Methyl undecanoate (Standard) is the analytical standard of Methyl undecanoate. This product is intended for research and analytical applications. Methyl undecanoate is an internal standard in gas-liquid chromatogram .
    Methyl undecanoate (Standard)
  • HY-108353S
    Isoprenaline-d7 acetate

    		Isotope-Labeled Compounds Others
    Isoprenalin-d7 acetate is an internal standard for the determination of isoproterenol by GC- or LC-MS .
    Isoprenaline-d7 acetate
  • HY-131676
    C17 Sphingomyelin (d18:1/17:0)

    SM (d18:1/17:0); Heptadecanoyl Sphingomyelin; N-Heptadecanoyl-D-erythro-Sphingosylphosphorylcholine

    		 Endogenous Metabolite Metabolic Disease
    C17 Sphingomyelin is a synthetic derivative of sphingomyelin that has been used as an internal standard for the quantification of sphingomyelin.
    C17 Sphingomyelin (d18:1/17:0)
  • HY-D1674
    Sulforhodamine G

    		Fluorescent Dye Others
    Sulforhodamine G is a fluorescent stain with broad dynamic ranges. Sulforhodamine G can be used for the research of protein stains .
    Sulforhodamine G
  • HY-W004285S
    Methyl undecanoate-d21

    		Isotope-Labeled Compounds Others
    Methyl undecanoate-d21 is the deuterium labeled Methyl undecanoate. Methyl undecanoate is an internal standard in gas-liquid chromatogram[1].
    Methyl undecanoate-d21
  • HY-N1393
    2-Methoxybenzoic acid

    NSC 3778; O-Methylsalicylic acid; Salicylic acid methyl ether

    		 Endogenous Metabolite Cancer
    2-Methoxybenzoic acid (NSC 3778) is used as an internal standard of salicylic acid and its putative biosynthetic precursors in cucumber leaves. Another known use is in the synthesis of Benextramine.
    2-Methoxybenzoic acid
  • HY-N1393R
    2-Methoxybenzoic acid (Standard)

    		Endogenous Metabolite Cancer
    2-Methoxybenzoic acid (Standard) is the analytical standard of 2-Methoxybenzoic acid. This product is intended for research and analytical applications. 2-Methoxybenzoic acid (NSC 3778) is used as an internal standard of salicylic acid and its putative biosynthetic precursors in cucumber leaves. Another known use is in the synthesis of Benextramine.
    2-Methoxybenzoic acid (Standard)
  • HY-W700539S
    N1-Acetyl triethylenetetramine-d4

    		Isotope-Labeled Compounds Others
    N1-Acetyl triethylenetetramine-d4 is deuterated N1-Acetyl triethylenetetramine and can be used as an internal standard in plasma extracts .
    N1-Acetyl triethylenetetramine-d4
  • HY-N0808R
    Camphor (Standard)

    		TRP Channel Influenza Virus Infection Inflammation/Immunology Cancer
    Camphor (Standard) is the analytical standard of Camphor. This product is intended for research and analytical applications. Camphor ((±)-Camphor) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative. However, Camphor is poisonous when ingested. Antiviral, antitussive, and anticancer activities . Camphor is a TRPV3 agonist .
    Camphor (Standard)
  • HY-N13079
    3-Epicinobufagin

    		Others Others
    3-Epicinobufagin (compound IX) can be used as an internal standard for the metabolism of Bufalin (HY-N0877), by detecting its content in serum and urine to provide feedback on the corresponding metabolic status .
    3-Epicinobufagin
  • HY-14865S
    Omadacycline-d9

    PTK 0796-d9; Amadacycline-d9

    		 Bacterial Isotope-Labeled Compounds Others
    Omadacycline-d9 (PTK 0796-d9; Amadacycline-d9) is the deuterium labeled Omadacycline (HY-14865) that can be used as the internal standard for the analysis of Omadacycline .
    Omadacycline-d9
  • HY-131389
    Cholesteryl heptadecanoate

    		Others Others
    Cholesteryl heptadecanoate is a cholesteryl ester internal standard that accurately determines the concentration of free cholesterol in cells without hydrolyzing triglycerides. Cholesteryl heptadecanoate can be used for the quantitative determination of cholesteryl esters by GC or LC mass spectrometry .
    Cholesteryl heptadecanoate
  • HY-138127
    Gendenafil

    		Biochemical Assay Reagents Others
    Gendenafil is an analog of Sildenafil (HY-15025). Gendenafil can be used as internal standard for quantitative analysis of Sildenafil (HY-15025), Tadalafil (HY-90009A), and Vardenafil (HY-B0442) .
    Gendenafil
  • HY-W019721R
    Cyclosporin D (Standard)

    		Nuclear Factor of activated T Cells (NFAT) Inflammation/Immunology
    Cyclosporin D (Standard) is the analytical standard of Cyclosporin D. This product is intended for research and analytical applications. Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A . Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc) .
    Cyclosporin D (Standard)
  • HY-N6726S1
    Fumonisin B3-13C34-1

    		Isotope-Labeled Compounds Others
    Fumonisin B3-13C34-1 is the isotopic internal standard of Fumonisin B3 (HY-N6726). Fumonisin B3 is a mycotoxin derived from fusarium fungi, a member of fumonisins .
    Fumonisin B3-13C34-1
  • HY-115705
    1,2,3-Tri-10(Z)-heptadecenoyl glycerol

    Glycerol tri-10(Z)-heptadecenoate; TG(17:1/17:1/17:1); Tri-10(Z)-heptadecenoin

    		 Biochemical Assay Reagents Others
    1,2,3-Tri-10(Z)-heptadecenoyl glycerol (TG(17:1/17:1/17:1)) is a biochemical assay reagent, which can be used as an internal standard for the quantification of biological triglyceride .
    1,2,3-Tri-10(Z)-heptadecenoyl glycerol
  • HY-18569S
    3-Indoleacetic acid-d5
    1 Publications Verification

    Indole-3-acetic acid-d5; 3-IAA-d5

    		 Endogenous Metabolite Isotope-Labeled Compounds Others
    3-Indoleacetic acid-d5 is the deuterium labeled 3-Indoleacetic acid. 3-Indoleacetic acid-d5 can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates[1].
    3-Indoleacetic acid-d5
  • HY-107935
    6α-Fluoroprednisolone

    Fluprednisolone

    		 Others Inflammation/Immunology
    6α-Fluoroprednisolone (Fluprednisolone) is an internal standard for methylprednisolone, prednisolone and prednisone. 6α-Fluoroprednisolone is an anti-inflammatory agent. 6α-Fluoroprednisolone can be used for congenital adrenal virilism and Addison's disease research .
    6α-Fluoroprednisolone
  • HY-N1393S
    2-Methoxybenzoic acid-13C6

    NSC 3778-13C6; O-Methylsalicylic acid-13C6; Salicylic acid methyl ether-13C6

    		 Isotope-Labeled Compounds Endogenous Metabolite Cancer
    2-Methoxybenzoic acid- 13C6 is the 13C-labeled 2-Methoxybenzoic acid. 2-Methoxybenzoic acid (NSC 3778) is used as an internal standard of salicylic acid and its putative biosynthetic precursors in cucumber leaves. Another known use is in the synthesis of Benextramine.
    2-Methoxybenzoic acid-13C6
  • HY-N2344R
    Procyanidin A1 (Standard)

    		PKC Inflammation/Immunology
    Procyanidin A1 (Standard) is the analytical standard of Procyanidin A1. This product is intended for research and analytical applications. Procyanidin A1 (Proanthocyanidin A1) is a procyanidin dimer, which inhibits degranulation downstream of protein kinase C activation or Ca2+ influx from an internal store in RBL-213 cells. Procyanidin A1 has antiallergic effects .
    Procyanidin A1 (Standard)
  • HY-W019721
    Cyclosporin D

    		Nuclear Factor of activated T Cells (NFAT) Inflammation/Immunology
    Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A . Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc) .
    Cyclosporin D
  • HY-W643167
    1,2,3-Tritridecanoylglycerol

    Glycerol Tritridecanoyl; 13:0 TAG; 13:0/13:0/13:0-TG

    		 Others Infection
    1,2,3-Tritridecanoyl glycerol is a synthetic triacylglycerol that contains tridecanoic acid in the sn-1, sn-2, and sn-3 positions. It has been used as a standard for the relative quantification of triacylglycerols in C. elegans fat stores. It has also been used as an internal standard for the quantification of triacylglycerols in the serum and liver of adult rat offspring receiving dietary conjugated linoleic acids during and after gestation.
    1,2,3-Tritridecanoylglycerol
  • HY-113958R
    Difethialone (Standard)

    		Others Others
    Difethialone (Standard) is the analytical standard of Difethialone. This product is intended for research and analytical applications. Difethialone (LM-2219) is an anticoagulant rodenticide. Difethialone shows high rodenticide activity in warfarin-sensitive and resistant strains of rats and mice. Difethialone interferes with the circulation of vitamin K in the liver, preventing the synthesis of coagulation factors, resulting in the inability of the blood to coagulate properly, ultimately causing internal bleeding and death. Difethialone can be used in studies of ecological impacts .
    Difethialone (Standard)
  • HY-109513R
    Ioxilan (Standard)

    		Biochemical Assay Reagents Others
    Ioxilan (Standard) is the analytical standard of Ioxilan. This product is intended for research and analytical applications. Ioxilan is a low-osmolar, nonionic and tri-iodinated diagnostic contrast agent. Ioxilan is also an X-ray contrast agent for excretory urography and contrast enhanced computed tomographic (CECT) imaging of the head and body. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs .
    Ioxilan (Standard)
  • HY-141579
    Sphingosine (d17:1)

    		Others Others
    Sphingosine (d17:1) is a 17-carbon sphingosine found in human skin. Sphingosine (d17:1) can be phosphorylated by sphingosine kinases to produce C-17 sphingosine-1-phosphate. Sphingosine C-17 was used as an internal standard for spectral analysis of sphingoid compounds .
    Sphingosine (d17:1)
  • HY-W706672R
    Propane-1,2,3-triyl tritricosanoate (Standard)

    		Endogenous Metabolite Metabolic Disease
    Propane-1,2,3-triyl tritricosanoate (Standard) is the analytical standard of Propane-1,2,3-triyl tritricosanoate. This product is intended for research and analytical applications. 1,2,3-Tritricosanoyl glycerol is a triacylglycerol that contains tricosanoic acid (HY-W009081) at the sn-1, sn-2, and sn-3 positions. It has been used as an internal standard for the quantification of fatty acids in the triglyceride component of human aortic endothelial cells (HAECs) grown in media supplemented with stearic and/or oleic acid.
    Propane-1,2,3-triyl tritricosanoate (Standard)
  • HY-W706672
    Propane-1,2,3-triyl tritricosanoate

    Glycerol Tritricosanoate; TG(23:0/23:0/23:0); Tritricosanoin

    		 Endogenous Metabolite Metabolic Disease
    1,2,3-Tritricosanoyl glycerol is a triacylglycerol that contains tricosanoic acid (HY-W009081) at the sn-1, sn-2, and sn-3 positions. It has been used as an internal standard for the quantification of fatty acids in the triglyceride component of human aortic endothelial cells (HAECs) grown in media supplemented with stearic and/or oleic acid.
    Propane-1,2,3-triyl tritricosanoate
  • HY-N0086R
    N6-Methyladenosine (Standard)

    		Influenza Virus Endogenous Metabolite Infection
    N6-Methyladenosine (Standard) is the analytical standard of N6-Methyladenosine. This product is intended for research and analytical applications. N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities. In Vitro: N6-methyladenosine (m6A) is selectively recognized by the human YTH domain family 2 (YTHDF2) protein to regulate mRNA degradation. N6-methyladenosine (m6A), a prevalent internal modification in the messenger RNA of all eukaryotes, is post-transcriptionally installed by m6A methyltransferase (e.g., MT-A70) within the consensus sequence of G(m6A)C (70%) or A(m6A)C (30%). N6-methyladenosine (m6A)-containing RNAs are greatly enriched in the YTHDF-bound portion and diminished in the flow-through portion . N6-methyladenosine (m6A), the most abundant internal RNA modification, functions in diverse biological processes, including regulation of embryonic stem cell self-renewal and differentiation. N6-methyladenosine (m6A) is a large protein complex, consisting in part of methyltransferase-like 3 (METTL3) and methyltransferase-like 14 (METTL14) catalytic subunits .
    N6-Methyladenosine (Standard)
  • HY-123023
    12(S)-HETE D8

    		Others Cancer
    12(S)-HETE D8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14 and 15 positions. 12(S)-HETE D8 is intended for use as an internal standard for the quantification of 12(S)-HETE by GC- or LC-mass spectrometry (MS). 12(S)-HETE D8 is the predominant lipoxygenase product of mammalian platelets. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.
    12(S)-HETE D8
  • HY-W750595
    6-(L-1,2,3-Trihydroxybutyl)-pterin

    		Others Cancer
    6-(L-1,2,3-Trihydroxybutyl)-pterin is a derivative of L-biopterin (HY-102015) and is the oxidized form of tetrahydro-L-biopterin (BH4) as well as D-biopterin. Co-ingestion of 6-(L-1,2,3-Trihydroxybutyl)-pterin (0.5%) with the carcinogen 4-dimethylaminoazobenzene reduces the incidence of 4-dimethylaminoazobenzene-induced liver tumors in rats. 6-(L-1,2,3-Trihydroxybutyl)-pterin has been used as an internal standard for the LC-MS quantification of biopterin and neopterin in rat plasma.
    6-(L-1,2,3-Trihydroxybutyl)-pterin
  • HY-P0048
    (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH

    Surfagon

    		 GnRH Receptor Others
    (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (Surfagon, Mwt 1167.34 Da) is an agonist of gonadotropin-releasing hormone (GnRH). (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH can be used as an internal standard for the LC-MS analysis of leuprorelide acetate. (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH has potential applications in biochemical analysis and fertility .
    (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH
  • HY-163691
    Antitumor agent-163

    		Carbonic Anhydrase Cancer
    Antitumor agent-163 (Compound 3) is a photosensitizer used in Molecular-Targeted Photodynamic Therapy (MT-PDT) targeting carbonic anhydrase IX (CAIX). Antitumor agent-163 inactivates CAIX protein via singlet oxygen under 540 nm wavelength light, without affecting internal standard proteins such as α-tubulin, β-actin, and proliferating cell nuclear antigen (PCNA). Antitumor agent-163 induces cell membrane damage, inhibits cell viability (IC50 is 0.2 and 0.05 μM for A549 and U87MG). Antitumor agent-163 exhibits antitumor efficacy in mouse model .
    Antitumor agent-163
  • HY-W127391
    1,2-Dilaurin

    (Rac)-1,2-Didodecanoylglycerol

    		 Biochemical Assay Reagents Others
    1,2-Dilaurin is a diacylglycerol containing lauric acid at the sn-1 and sn-2 positions. It has been used as an internal standard for the quantification of diglycerides in rat desheathed sciatic nerves. [1] Monomolecular films containing 1,2-dilauroyl-rac-glycerol have been used as substrates to measure surface pressure and the effect of pancreatic procolipase and colipase on porcine pancreatic lipase activity. [2] References: [1]. Zhu, X. and Eichberg, J. 1,2-Diacylglycerol content and its arachidonyl-containing molecular species are reduced in the sciatic nerve of streptozotocin-induced diabetic rats. J. Neurochemistry. 55(3), 1087-1090 (1990).[2]. Wieloch, T., Borgstr m, B., Piéroni, G. et al. Porcine trypsinogen and its trypsin-activated form: lipid binding and lipase activation on monomolecular membranes. FEBS Express. 128(2), 217-220 (1981).
    1,2-Dilaurin

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