Sphingosine (d17:1)

Cat. No.: HY-141579 Purity: 99.93%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

Sphingosine (d17:1) is a 17-carbon sphingosine found in human skin. Sphingosine (d17:1) can be phosphorylated by sphingosine kinases to produce C-17 sphingosine-1-phosphate. Sphingosine C-17 was used as an internal standard for spectral analysis of sphingoid compounds.

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Sphingosine (d17:1) Chemical Structure

CAS No. : 6918-48-5

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	Get quote
50 mg	Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

Molecular Weight

285.47

Formula

C₁₇H₃₅NO₂

CAS No.

6918-48-5

Appearance

Solid

Color

White to off-white

SMILES

OC[C@H](N)[C@H](O)/C=C/CCCCCCCCCCCC

Initial Source

Animals

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMF : 10 mg/mL (35.03 mM; Need ultrasonic and warming)

DMSO : ≥ 2 mg/mL (7.01 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.5030 mL	17.5150 mL	35.0299 mL
5 mM	0.7006 mL	3.5030 mL	7.0060 mL
10 mM	0.3503 mL	1.7515 mL	3.5030 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

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In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.93%

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Data Sheet (265 KB) SDS (393 KB)

COA (239 KB) RP-HPLC (191 KB) LCMS (94 KB)

Handling Instructions (2659 KB)

References

[1]. Stewart ME, et al. Free sphingosines of human skin include 6-hydroxysphingosine and unusually long-chain dihydrosphingosines. J Invest Dermatol. 1995 Oct;105(4):613-8. [Content Brief]

[2]. Hong JH, et al. K6PC-5, a direct activator of sphingosine kinase 1, promotes epidermal differentiation through intracellular Ca2+ signaling. J Invest Dermatol. 2008 Sep;128(9):2166-78. [Content Brief]

[3]. Choi CH, et al. Sphingosine 1-phosphate and sphingosine kinase activity during chicken embryonic development. Arch Pharm Res. 2007 Apr;30(4):502-6. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / DMF	1 mM	3.5030 mL	17.5150 mL	35.0300 mL	87.5749 mL
DMSO / DMF	5 mM	0.7006 mL	3.5030 mL	7.0060 mL	17.5150 mL
DMF	10 mM	0.3503 mL	1.7515 mL	3.5030 mL	8.7575 mL
	15 mM	0.2335 mL	1.1677 mL	2.3353 mL	5.8383 mL
	20 mM	0.1751 mL	0.8757 mL	1.7515 mL	4.3787 mL
	25 mM	0.1401 mL	0.7006 mL	1.4012 mL	3.5030 mL
	30 mM	0.1168 mL	0.5838 mL	1.1677 mL	2.9192 mL