2. GPCR/G Protein Stem Cell/Wnt MAPK/ERK Pathway
  3. Bradykinin Receptor ERK
  4. [Tyr8] Bradykinin

[Tyr8] Bradykinin is a B2 kinin receptor agonist. [Tyr8] Bradykinin also stimulates ERK1/2 phosphorylation. [Tyr8] Bradykinin can be used as an internal standard.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

[Tyr8] Bradykinin Chemical Structure

[Tyr8] Bradykinin Chemical Structure

CAS No. : 32222-00-7

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5 mg USD 140 In-stock
10 mg USD 225 In-stock
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Based on 1 publication(s) in Google Scholar

[Tyr8] Bradykinin Related Antibodies

Top Publications Citing Use of Products

View All Bradykinin Receptor Isoform Specific Products:

View All Isoforms
Bradykinin B1 Receptor (B1R) Bradykinin B2 Receptor (B2R)

View All ERK Isoform Specific Products:

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ERK ERK1 ERK2 ERK5 ERK8

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

[Tyr8] Bradykinin is a B2 kinin receptor agonist. [Tyr8] Bradykinin also stimulates ERK1/2 phosphorylation. [Tyr8] Bradykinin can be used as an internal standard[1].

IC50 & Target

ERK1

 

ERK2

 

In Vitro

[Tyr8] Bradykinin (10 nM, 2 min) produces a rapid increase in phosphorylated ERK1/2[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

[Tyr8] Bradykinin Related Antibodies

Western Blot Analysis[1]

Cell Line: Serum-deprived trabecular meshwork cells
Concentration: 10 nM
Incubation Time: 2 min
Result: Produced a rapid increase in phosphorylated ERK1/2 that was equivalent in magnitude to that observed for Bradykinin (HY-P0206).
Molecular Weight

1076.21

Formula

C50H73N15O12
CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

RPPGFSPYR
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (92.92 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9292 mL 4.6459 mL 9.2919 mL
5 mM 0.1858 mL 0.9292 mL 1.8584 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.9292 mL 4.6459 mL 9.2919 mL 23.2297 mL
5 mM 0.1858 mL 0.9292 mL 1.8584 mL 4.6459 mL
10 mM 0.0929 mL 0.4646 mL 0.9292 mL 2.3230 mL
15 mM 0.0619 mL 0.3097 mL 0.6195 mL 1.5486 mL
20 mM 0.0465 mL 0.2323 mL 0.4646 mL 1.1615 mL
25 mM 0.0372 mL 0.1858 mL 0.3717 mL 0.9292 mL
30 mM 0.0310 mL 0.1549 mL 0.3097 mL 0.7743 mL
40 mM 0.0232 mL 0.1161 mL 0.2323 mL 0.5807 mL
50 mM 0.0186 mL 0.0929 mL 0.1858 mL 0.4646 mL
60 mM 0.0155 mL 0.0774 mL 0.1549 mL 0.3872 mL
80 mM 0.0116 mL 0.0581 mL 0.1161 mL 0.2904 mL
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[Tyr8] Bradykinin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[Tyr8] Bradykinin32222-00-7Bradykinin ReceptorERKExtracellular signal regulated kinasesinternal standardBradykininphosphorylationInhibitorinhibitorinhibit

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