2. Protein Tyrosine Kinase/RTK
  3. VEGFR
  4. Abicipar pegol

Abicipar pegol  (Synonyms: AGN-150998; MP0112)

Cat. No.: HY-P99416

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Abicipar pegol (AGN-150998, MP0112) is an anti-VEGF DARPin molecule, a novel class of small proteins containing ankyrin repeat domains engineered to bind with high specificity and affinity to target proteins. Abicipar pegol effectively inhibits angiogenesis and vascular permeability and is used in the study of diseases related to ocular inflammation by intravitreal injection, reducing mean retinal thickness and leakage area.

For research use only. We do not sell to patients.

CAS No. : 1327278-94-3

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Abicipar pegol Related Antibodies

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Description

Abicipar pegol (AGN-150998, MP0112) is an anti-VEGF DARPin molecule, a novel class of small proteins containing ankyrin repeat domains engineered to bind with high specificity and affinity to target proteins. Abicipar pegol effectively inhibits angiogenesis and vascular permeability and is used in the study of diseases related to ocular inflammation by intravitreal injection, reducing mean retinal thickness and leakage area[1][2].

Species

Human
Clinical Trial
CAS No.
SMILES

[Abicipar pegol]
Storage

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Format
  • Alternative to antigen receptors (domain scaffold: ANK, ankyrin repeats)-pegol
Purity & Documentation
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Abicipar pegol Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Abicipar pegol1327278-94-3AGN-150998 MP0112AGN150998AGN 150998MP0112MP 0112MP-0112VEGFRVascular endothelial growth factor receptorVEGFDARPinangiogenesisvascular permeabilityocular inflammationInhibitorinhibitorinhibit

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