2. Apoptosis
  3. Apoptosis
  4. Chb-M′

Chb-M′ (Compound Conjugate 1) covalently binds to the RUNX-binding sequences, and inhibits the binding of RUNX proteins to their target sites. Chb-M′ induces the p53-dependent apoptosis and inhibits cancer cell growth. Chb-M′ inhibits tumor growth in PANC-1 xenograft mice.

For research use only. We do not sell to patients.

Chb-M′ Chemical Structure

Chb-M′ Chemical Structure

CAS No. : 2177285-35-5

Size Price Stock
1 mg USD 860 Ask For Quote & Lead Time
5 mg USD 2150 Ask For Quote & Lead Time
10 mg USD 3460 Ask For Quote & Lead Time

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Chb-M′ Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Chb-M′ (Compound Conjugate 1) covalently binds to the RUNX-binding sequences, and inhibits the binding of RUNX proteins to their target sites. Chb-M′ induces the p53-dependent apoptosis and inhibits cancer cell growth. Chb-M′ inhibits tumor growth in PANC-1 xenograft mice[1].

IC50 & Target

RUNX[1]
Molecular Weight

1524.52

Formula

C71H88Cl2N24O11
CAS No.
SMILES

O=C(CCCNC(C1=NC(NC(C2=NC(NC(C3=CC(NC(C4=NC(NC(CCNC(CCCC5=CC=C(C=C5)N(CCCl)CCCl)=O)=O)=CN4C)=O)=CN3C)=O)=CN2C)=O)=CN1C)=O)NC6=CN(C(C(NC7=CN(C(C(NC8=CN(C(C(NC9=CN(C(C(NCCCN(C)C)=O)=C9)C)=O)=C8)C)=O)=C7)C)=O)=C6)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Chb-M′ Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Chb-M′2177285-35-5RUNX-IN-1ApoptosiscancertumorcovalentmedulloblastomaPANC-1 xenograftpancreatic cancerInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Chb-M′
Cat. No.:
HY-155990
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.