PLAC1 - placenta enriched 1 Gene

Homo sapiens

Also known as CT92; OOSP2B; OOSP2L

Gene ID: 10761 | Gene type: protein coding

About PLAC1

Cytogenetic location: Xq26.3 Genomic coordinates (GRCh38): X:134,565,838-134,764,322 (from NCBI)

This gene has 4 transcripts (splice variants), 64 orthologues and 2 paralogues. Restricted expression toward placenta (RPKM 19.2).

Summary

Involved in placenta development. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

PLAC1 Products(4)

mRNA	Protein	Name
NM_001316887.2	NP_001303816.1	placenta-specific protein 1 precursor
NM_001316888.2	NP_001303817.1	placenta-specific protein 1 precursor
NM_001316889.2	NP_001303818.1	placenta-specific protein 1 precursor
NM_021796.4	NP_068568.1	placenta-specific protein 1 precursor

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in placenta development	IEP IEP: Inferred from expression pattern	10995572	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PLAC1 Protein Structure

Zona_pellucida

0
100
200
212 a.a.

Protein Preferred Names

Protein Names

placenta-specific protein 1

cancer/testis antigen 92

Related Diseases

Diseases

Alias

Pre-Eclampsia

Preeclampsia	Gestational Hypertension
Hypertension Induced By Pregnancy	Pre-Eclamptic Toxaemia
Pregnancy Associated Hypertension	Proteinuric Hypertension Of Pregnancy
Hypertension, Pregnancy-Induced, Susceptibility To	Preeclampsia/Eclampsia
Pregnancy Toxemia	Toxaemia Of Pregnancy
Gestational Proteinuric Hypertension	Pregnancy-Induced Hypertension
Toxemia Of Pregnancy	Preeclampsia, Susceptibility To
Transient Hypertension Of Pregnancy	Gestational [Pregnancy-Induced] Hypertension Without Significant Proteinuria
Gestational Hypertension Nos	Mild Proteinuric Hypertension Of Pregnancy
Pih - [Pregnancy-Induced Hypertension]	Pregnancy-Induced Hypertension Nos
Gestational [Pregnancy-Induced] Hypertension With Significant Proteinuria	Pe - [Pre-Eclampsia]
Pre-Eclampsia Nos	Pre-Eclamptic Nos
Pregnancy Pre-Eclampsia	Puerperal Pre-Eclampsia
Pre-Eclampsia Toxaemia	Toxaemia In Pregnancy
Pet - [Pre-Eclamptic Toxaemia]	Maternal Toxaemia

Cervical Adenosquamous Carcinoma

Adenosquamous Carcinoma Of Cervix

Adenosquamous Cell Carcinoma Of The Cervix Uteri

Endometrium Carcinoma In Situ

Carcinoma In Situ Of Endometrium

Endometrial Carcinoma In Situ

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10640	PLAC1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	PLAC1	VGNC	VGNC:76159
Mus musculus	PLAC1	MGD	MGI:1926287
Rattus norvegicus	PLAC1	RGD	RGD:1563777
Canis familiaris	PLAC1	VGNC	VGNC:44635
Bos taurus	PLAC1	VGNC	VGNC:32968

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