SOGA1 - suppressor of glucose, autophagy associated 1 Gene

Homo sapiens

Also known as SOGA; KIAA0889; C20orf117

Gene ID: 140710 | Gene type: protein coding

About SOGA1

This gene has 4 transcripts (splice variants), 267 orthologues and 2 paralogues. Ubiquitous expression in thyroid (RPKM 9.7), brain (RPKM 6.2) and 22 other tissues.

Summary

Predicted to be involved in Insulin Receptor signaling pathway; negative regulation of gluconeogenesis; and regulation of Autophagy. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

SOGA1 Products(2)

mRNA	Protein	Name
NM_080627.4	NP_542194.2	protein SOGA1 isoform 1
NM_199181.3	NP_954650.2	protein SOGA1 isoform 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in chromosome segregation	IMP IMP: Inferred from mutant phenotype	33587225	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in extracellular space	IDA IDA: Inferred from direct assay	20813965	GOA
located in microtubule	IDA IDA: Inferred from direct assay	33587225	GOA
located in midbody	IDA IDA: Inferred from direct assay	33587225	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SOGA1 Protein Structure

SOGA

DUF4482

0
300
600
900
1200
1500
1661 a.a.

Protein Preferred Names

Protein Names

protein SOGA1

SOGA family member 1

Related Diseases

Diseases

Alias

Enterokinase Deficiency

Enteropeptidase Deficiency	Congenital Enterokinase Deficiency
Congenital Enteropathy Due To Enteropeptidase Deficiency	Deficiency Of Enteropeptidase
ENTKD

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13562	SOGA1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SOGA1	VGNC	VGNC:46655
Bos taurus	SOGA1	VGNC	VGNC:35127
Felis catus	SOGA1	VGNC	VGNC:65567
Macaca mulatta	SOGA1	VGNC	VGNC:77715
Mus musculus	SOGA1	MGD	MGI:2444575
Rattus norvegicus	SOGA1	RGD	RGD:1563627

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