2. Gene
  3. TMEM64 - transmembrane protein 64 Gene

TMEM64 - transmembrane protein 64 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 169200 | Gene type: protein coding

About TMEM64

This gene has 7 transcripts (splice variants), 188 orthologues and 2 paralogues. Ubiquitous expression in thyroid (RPKM 12.6), fat (RPKM 10.6) and 25 other tissues.

Summary

Predicted to be involved in negative regulation of canonical Wnt signaling pathway; negative regulation of osteoblast differentiation; and positive regulation of fat cell differentiation. Predicted to act upstream of or within several processes, including positive regulation of bone resorption; positive regulation of osteoclast differentiation; and regulation of ATPase activity. Predicted to be located in endoplasmic reticulum. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM64 Products(2)

mRNA Protein Name
NM_001008495.4 NP_001008495.2 transmembrane protein 64 isoform 1
NM_001146273.1 NP_001139745.1 transmembrane protein 64 isoform 2

TMEM64 Protein Structure

SNARE_assoc

SNARE_assoc: SNARE associated Golgi protein (180 - 294)

  • 0
  • 100
  • 200
  • 300
  • 380 a.a.
Protein Preferred Names Protein Names

transmembrane protein 64

Related Diseases

Diseases Alias
Tetraamelia Syndrome

Tetra-Amelia Syndrome

Tetraamelia-Multiple Malformations Syndrome

Tetra-Amelia

Tetra-Amelia, Autosomal Recessive

Tetraamelia, Autosomal Recessive

Total Amelia

Zimmer Phocomelia

Tetams

Zimmer Taub Sova Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14735 TMEM64 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris TMEM64 VGNC VGNC:54121
Felis catus TMEM64 VGNC VGNC:81680
Mus musculus TMEM64 MGD MGI:2140359
Rattus norvegicus TMEM64 RGD RGD:1596128
Macaca mulatta TMEM64 VGNC VGNC:84127
Bos taurus TMEM64 VGNC VGNC:59370