2. Gene
  3. HS3ST5 - heparan sulfate-glucosamine 3-sulfotransferase 5 Gene

HS3ST5 - heparan sulfate-glucosamine 3-sulfotransferase 5 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as 3OST5; 3-OST-5; HS3OST5; NBLA04021

Gene ID: 222537 | Gene type: protein coding

About HS3ST5

Cytogenetic location: 6q21-q22.1 Genomic coordinates (GRCh38): 6:114,055,596-114,343,023 (from NCBI)

This gene has 2 transcripts (splice variants), 196 orthologues and 10 paralogues. Low expression observed in reference dataset.

Summary

HS3ST5 belongs to a group of heparan sulfate 3-O-sulfotransferases (EC 2.8.2.23) that transfer sulfate from 3-prime-phosphoadenosine 5-prime phosphosulfate (PAPS) to heparan sulfate and heparin (Mochizuki et al., 2003 [PubMed 12740361]).[supplied by OMIM, Mar 2008]

HS3ST5 Products(10)

mRNA Protein Name
NM_001387039.1 NP_001373968.1 heparan sulfate glucosamine 3-O-sulfotransferase 5
NM_001387040.1 NP_001373969.1 heparan sulfate glucosamine 3-O-sulfotransferase 5
NM_001387041.1 NP_001373970.1 heparan sulfate glucosamine 3-O-sulfotransferase 5
NM_001387042.1 NP_001373971.1 heparan sulfate glucosamine 3-O-sulfotransferase 5
NM_001387043.1 NP_001373972.1 heparan sulfate glucosamine 3-O-sulfotransferase 5
NM_001387044.1 NP_001373973.1 heparan sulfate glucosamine 3-O-sulfotransferase 5
NM_001387045.1 NP_001373974.1 heparan sulfate glucosamine 3-O-sulfotransferase 5
NM_001387046.1 NP_001373975.1 heparan sulfate glucosamine 3-O-sulfotransferase 5
NM_001387047.1 NP_001373976.1 heparan sulfate glucosamine 3-O-sulfotransferase 5
NM_153612.4 NP_705840.2 heparan sulfate glucosamine 3-O-sulfotransferase 5

HS3ST5 Protein Structure

Sulfotransfer_1

Sulfotransfer_1: Sulfotransferase domain (91 - 335)

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  • 346 a.a.
Protein Preferred Names Protein Names

heparan sulfate glucosamine 3-O-sulfotransferase 5

h3-OST-5

Related Diseases

Diseases Alias
Breast Pericanalicular Fibroadenoma

Pericanalicular Fibroadenoma

Pericanalicular Fibroadenoma Of Breast
Syndromic X-Linked Intellectual Disability Najm Type

Mental Retardation And Microcephaly With Pontine And Cerebellar Hypoplasia

Micpch

X-Linked Intellectual Disability-Microcephaly-Pontocerebellar Hypoplasia Syndrome
Omodysplasia

Omodysplasia Type 1

Omodysplasia 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06381 HS3ST5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus HS3ST5 RGD RGD:1306379
Macaca mulatta HS3ST5 VGNC VGNC:104404
Bos taurus HS3ST5 VGNC VGNC:29960
Canis familiaris HS3ST5 VGNC VGNC:41793
Mus musculus HS3ST5 MGD MGI:2441996
Felis catus HS3ST5 VGNC VGNC:62843