PHF3 - PHD finger protein 3 Gene

Homo sapiens

Gene ID: 23469 | Gene type: protein coding

About PHF3

Cytogenetic location: 6q12 Genomic coordinates (GRCh38): 6:63,635,802-63,726,011 (from NCBI)

This gene has 12 transcripts (splice variants), 218 orthologues and 2 paralogues. Ubiquitous expression in testis (RPKM 15.6), thyroid (RPKM 14.4) and 25 other tissues.

Summary

This gene encodes a member of a PHD finger-containing gene family. This gene may function as a transcription factor and may be involved in glioblastomas development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

PHF3 Products(6)

mRNA	Protein	Name
NM_001290259.2	NP_001277188.1	PHD finger protein 3 isoform 2
NM_001290260.2	NP_001277189.1	PHD finger protein 3 isoform 3
NM_001370348.2	NP_001357277.1	PHD finger protein 3 isoform 1
NM_001370349.2	NP_001357278.1	PHD finger protein 3 isoform 2
NM_001370350.2	NP_001357279.1	PHD finger protein 3 isoform 4
NM_015153.4	NP_055968.1	PHD finger protein 3 isoform 1

PHF3 Protein Structure

PHD

TFIIS_M

SPOC

0
400
800
1200
1600
2039 a.a.

Protein Preferred Names

Protein Names

PHD finger protein 3

Related Diseases

Diseases

Alias

Retinitis Pigmentosa 25

RP25	Retinitis Pigmentosa-25
Retinitis Pigmentosa, Type 25

Cone-Rod Dystrophy 2

Cone-Rod Dystrophy	CORD2
Cone-Rod Retinal Dystrophy	Rcrd2
Cone-Rod Retinal Dystrophy 2	Crd2
Cord	Crd
Retinal Cone-Rod Dystrophy	Cone-Rod Retinal Dystrophy-2
Retinal Cone-Rod Dystrophy 2	Tapetoretinal Degeneration
Cone-Rod Degeneration	Cone Rod Dystrophy
Dystrophy, Cone-Rod	Dystrophy, Cone-Rod, Type 2
Retinitis Pigmentosa	Retinitis Pigmentosa 2
Progressive Cone-Rod Dystrophy

Retinitis Pigmentosa

RP	Rod-Cone Dystrophy
Autosomal Recessive Retinitis Pigmentosa	Non-Syndromic Retinitis Pigmentosa
Pericentral Pigmentary Retinopathy	Pigmentary Retinopathy
Tapetoretinal Degeneration	Rcd
Retinitis Pigmentosa Autosomal Recessive	ARRP
Retinitis Pigmentosa, Autosomal Recessive	Retinitis Pigmentosa 1

Fundus Dystrophy

Retinal Dystrophy	Retinal Dystrophies
Dystrophy, Retinal

Glioblastoma

Glioblastoma Multiforme	Gbm
Adult Glioblastoma Multiforme	Grade Iv Adult Astrocytic Tumor
Primary Glioblastoma Multiforme	Spongioblastoma Multiforme
Adult Glioblastoma	Primary Glioblastoma

Combined Oxidative Phosphorylation Deficiency 24

COXPD24	Combined Oxidative Phosphorylation Defect Type 24
Oxidative Phosphorylation Deficiency, Combined, Type 24

Combined Oxidative Phosphorylation Deficiency 20

COXPD20	Combined Oxidative Phosphorylation Defect Type 20
Oxidative Phosphorylation Deficiency, Combined, Type 20

Autism Spectrum Disorder

Asd	Autism Spectrum Disorders
Autistic Continuum	Pervasive Developmental Disorder
Pervasive Development Disorder	Autistic Behavior
Autistic Disorder	Autistic
Autistic Disorder Of Childhood Onset	Infantile Autism
Childhood Autism	Kanner Syndrome
Pervasive Developmental Delay Nos	Pervasive Developmental Disorder, Not Otherwise Specified

Autism

Autistic Disorder	Autism Susceptibility 1
Childhood Autism	Autistic Disorder Of Childhood Onset
Infantile Autism	Kanner'S Syndrome
Autistic

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10427	PHF3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	PHF3	VGNC	VGNC:32825
Macaca mulatta	PHF3	VGNC	VGNC:75975
Felis catus	PHF3	VGNC	VGNC:68823
Mus musculus	PHF3	MGD	MGI:2446126
Rattus norvegicus	PHF3	RGD	RGD:1304925
Canis familiaris	PHF3	VGNC	VGNC:44490

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