2. Gene
  3. RNF149 - ring finger protein 149 Gene

RNF149 - ring finger protein 149 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as DNAPTP2

Gene ID: 284996 | Gene type: protein coding

About RNF149

This gene has 6 transcripts (splice variants), 128 orthologues and 9 paralogues. Ubiquitous expression in bone marrow (RPKM 14.1), appendix (RPKM 12.5) and 25 other tissues.

Summary

Predicted to enable ubiquitin protein Ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within cellular response to xenobiotic stimulus; negative regulation of MAPK cascade; and regulation of protein stability. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

RNF149 Products(1)

mRNA Protein Name
NM_173647.4 NP_775918.2 E3 ubiquitin-protein ligase RNF149 precursor

RNF149 Protein Structure

PA

PA: PA domain (110 - 173)

zf-RING_2

zf-RING_2: Ring finger domain (268 - 310)

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Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase RNF149

DNA polymerase-transactivated protein 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12057 RNF149 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus RNF149 VGNC VGNC:34029
Mus musculus RNF149 MGD MGI:2677438
Rattus norvegicus RNF149 RGD RGD:1308460
Macaca mulatta RNF149 VGNC VGNC:106213