TRNP1 - TMF1 regulated nuclear protein 1 Gene

Homo sapiens

Also known as TNRP; TRNP; C1orf225

Gene ID: 388610 | Gene type: protein coding

About TRNP1

Cytogenetic location: 1p36.11 Genomic coordinates (GRCh38): 1:26,993,692-27,000,886 (from NCBI)

This gene has 2 transcripts (splice variants) and 132 orthologues. Biased expression in stomach (RPKM 40.7), esophagus (RPKM 17.0) and 7 other tissues.

Summary

Predicted to enable DNA binding activity. Predicted to be involved in several processes, including cerebellar cortex morphogenesis; neural precursor cell proliferation; and regulation of cell population proliferation. Predicted to be active in nucleus. Predicted to colocalize with euchromatin. [provided by Alliance of Genome Resources, Apr 2022]

TRNP1 Products(1)

mRNA	Protein	Name
NM_001013642.3	NP_001013664.2	TMF-regulated nuclear protein 1

Protein Preferred Names

Protein Names

TMF-regulated nuclear protein 1

Related Diseases

Diseases

Alias

Lissencephaly 2

Norman-Roberts Syndrome	Lissencephaly Syndrome, Norman-Roberts Type
LIS2	Lissencephaly With Cerebellar Hypoplasia
Lch	Lissencephaly Syndrome Norman-Roberts Type
Norman Roberts Lissencephaly Syndrome	Lissencephaly 3
Lis3	Microlissencephaly Type A
Norman-Roberts Lissencephaly Syndrome	Lissencephaly, Type 2
Cobblestone Lissencephaly

Periventricular Nodular Heterotopia

Periventricular Heterotopia	Pvnh
Familial Nodular Heterotopia	Heterotopia, Periventricular
Periventricular Heterotopia, X-Linked

Primary Autosomal Recessive Microcephaly

Autosomal Recessive Primary Microcephaly	Mcph
True Microcephaly	Microcephalia Vera
Microcephaly Vera	Microcephaly Primary Hereditary
Microcephaly, Primary, Autosomal Recessive	Primary Microcephaly

Congenital Nervous System Abnormality

Congenital Neurologic Anomaly

Congenital Nervous System Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15098	TRNP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	TRNP1	VGNC	VGNC:79946
Felis catus	TRNP1	VGNC	VGNC:107685
Bos taurus	TRNP1	VGNC	VGNC:107002
Mus musculus	TRNP1	MGD	MGI:1916789
Rattus norvegicus	TRNP1	RGD	RGD:1582917

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