FOXB2 - forkhead box B2 Gene

Homo sapiens

Also known as FKH4; bA159H20.4

Gene ID: 442425 | Gene type: protein coding

About FOXB2

Cytogenetic location: 9q21.2 Genomic coordinates (GRCh38): 9:77,019,655-77,020,953 (from NCBI)

This gene has 1 transcript (splice variant), 184 orthologues and 42 paralogues.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of chromatin. [provided by Alliance of Genome Resources, Apr 2022]

FOXB2 Products(1)

mRNA	Protein	Name
NM_001013735.1	NP_001013757.1	forkhead box protein B2

FOXB2 Protein Structure

Forkhead

0
100
200
300
400
432 a.a.

Protein Preferred Names

Protein Names

forkhead box protein B2

Related Diseases

Diseases

Alias

Testicular Germ Cell Cancer

Germ Cell Tumor Of Testis	Testicular Germ Cell Tumor
Testicular Germ Cell Neoplasm	Testicular Malignant Germ Cell Tumor

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05040	FOXB2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	FOXB2	VGNC	VGNC:40947
Macaca mulatta	FOXB2	VGNC	VGNC:72555
Bos taurus	FOXB2	VGNC	VGNC:55046
Mus musculus	FOXB2	MGD	MGI:1347468
Felis catus	FOXB2	VGNC	VGNC:102928
Rattus norvegicus	FOXB2	RGD	RGD:1585019

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