2. Gene
  3. DDX43 - DEAD-box helicase 43 Gene

DDX43 - DEAD-box helicase 43 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CT13; HAGE

Gene ID: 55510 | Gene type: protein coding

About DDX43

Cytogenetic location: 6q13 Genomic coordinates (GRCh38): 6:73,394,828-73,417,566 (from NCBI)

This gene has 3 transcripts (splice variants), 33 orthologues and 38 paralogues. Biased expression in testis (RPKM 12.4), placenta (RPKM 1.9) and 3 other tissues.

Summary

The protein encoded by this gene is an ATP-dependent RNA helicase in the DEAD-box family and displays tumor-specific expression. [provided by RefSeq, Jul 2008]

DDX43 Products(1)

mRNA Protein Name
NM_018665.3 NP_061135.2 probable ATP-dependent RNA helicase DDX43
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DDX43 Protein Structure

KH_1

KH_1: KH domain (76 - 128)

DEAD

DEAD: DEAD/DEAH box helicase (266 - 436)

Helicase_C

Helicase_C: Helicase conserved C-terminal domain (511 - 582)

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  • 648 a.a.
Protein Preferred Names Protein Names

probable ATP-dependent RNA helicase DDX43

DEAD (Asp-Glu-Ala-Asp) box polypeptide 43

Related Diseases

Diseases Alias
Latent Syphilis

Syphilis, Latent
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03651 DDX43 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus DDX43 VGNC VGNC:102412
Mus musculus DDX43 MGD MGI:3642857
Rattus norvegicus DDX43 RGD RGD:1586947
Macaca mulatta DDX43 VGNC VGNC:71662