2. Academic Validation
  3. [Role of Hepatocyte Growth Factor in Wound Repair]

[Role of Hepatocyte Growth Factor in Wound Repair]

  • Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2018 Dec 20;40(6):822-826. doi: 10.3881/j.issn.1000-503X.10246.
Xiao Ying Lin 1,  Hong Wang 1,  Yuan Tan 1
Affiliations

Affiliation

  • 1 Department of Burns,the Second Affiliated Hospital,Kunming Medical University, Burn Institute of Yunnan Province,Kunming 650101,China.
PMID: 30606395 DOI: 10.3881/j.issn.1000-503X.10246
Abstract

Hepatocyte growth factor (HGF) is a multifunctional cytokine that is related to many diseases. HGF mainly contributes to cell migration,proliferation,and survival and regulates vascular angiogenesis,matrix deposition,and degradation of wound healing. HGF also promotes wound reepithelialization and reduces scar formation. This review article summarizes the role of HGF in wound repair and the relationship between HGF and other growth factors,especially when applied for the clinical treatment of chronic skin ulcers.

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