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  3. Claudin-11/CLDN11 Protein, Human (Cell-Free, His)

Claudin-11/CLDN11 Protein, Human (Cell-Free, His)

Cat. No.: HY-P702246
Handling Instructions

Claudin-11/CLDN11 Protein plays a crucial role in tightly closing intercellular spaces in tight junctions, facilitated by its calcium-independent cell-adhesion capabilities. Interacting with tetraspanin-3/TSPAN3 suggests potential collaboration in cellular processes. CLDN11's associations with OCLN highlight its involvement in molecular interactions, contributing to the structural integrity and functional regulation of tight junctions. Claudin-11/CLDN11 Protein, Human (Cell-Free, His) is the recombinant human-derived CLDN11 protein, expressed by E. coli Cell-free , with N-10*His labeled tag.

For research use only. We do not sell to patients.

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Description

Claudin-11/CLDN11 Protein plays a crucial role in tightly closing intercellular spaces in tight junctions, facilitated by its calcium-independent cell-adhesion capabilities. Interacting with tetraspanin-3/TSPAN3 suggests potential collaboration in cellular processes. CLDN11's associations with OCLN highlight its involvement in molecular interactions, contributing to the structural integrity and functional regulation of tight junctions. Claudin-11/CLDN11 Protein, Human (Cell-Free, His) is the recombinant human-derived CLDN11 protein, expressed by E. coli Cell-free , with N-10*His labeled tag.

Background

Claudin-11 (CLDN11) assumes a crucial role in the precise closure of the intercellular space within tight junctions, primarily facilitated by its calcium-independent cell-adhesion capabilities. This protein also engages in interactions with tetraspanin-3/TSPAN3, indicating potential collaborative roles within cellular processes. Furthermore, CLDN11 forms associations with OCLN, as observed in experimental findings, elucidating its involvement in molecular interactions that contribute to the structural integrity and functional regulation of tight junctions.

Species

Human

Source

E. coli Cell-free

Tag

N-10*His

Accession

O75508 (M1-V207)

Gene ID

5010

Molecular Construction
N-term
10*His
CLDN11 (M1-V207)
Accession # O75508
C-term
Synonyms
Claudin-11; Oligodendrocyte-specific protein
AA Sequence

MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVMATGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRRAQLAGVLLILLALCALVATIWFPVCAHRETTIVSFGYSLYAGWIGAVLCLVGGCVILCCAGDAQAFGENRFYYTAGSSSPTHAKSAHV

Molecular Weight

23.5 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

Claudin-11/CLDN11 Protein, Human (Cell-Free, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
Claudin-11/CLDN11 Protein, Human (Cell-Free, His)
Cat. No.:
HY-P702246
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