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PGR

" in MedChemExpress (MCE) Product Catalog:
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  • HY-P701217
    PTGR1 Protein, Human (HEK293, His)

    DIG-1; LTB4DH; PGR1; ZADH3

    		 Human HEK293
    PTGR1, a NAD(P)H-dependent oxidoreductase, efficiently metabolizes inflammatory eicosanoids like prostaglandins, leukotrienes, and lipoxins. It actively catalyzes the reduction of the 13,14 double bond in various 15-oxoPGs, including 15-oxo-PGE1 and 15-oxo-PGF2-alpha. PTGR1 also plays a role in detoxifying alkenals and ketones, exhibiting preference for medium-chain length substrates like (2E)-decenal. This multifaceted enzymatic activity underscores PTGR1's significant role in regulating inflammation and detoxifying cytotoxic lipid constituents, contributing to cellular homeostasis. PTGR1 Protein, Human (HEK293, His) is the recombinant human-derived PTGR1 protein, expressed by HEK293, with C-6*His labeled tag. The total length of PTGR1 Protein, Human (HEK293, His) is 329 a.a., with molecular weight of ~38 kDa.
  • HY-P76960
    GPR114 Protein, Human (HEK293, Fc)

    Adhesion G-protein coupled receptor G5; G-protein coupled receptor 114; ADGRG5; PGR27

    		 Human HEK293
    GPR114, an adhesion G protein-coupled receptor (GPCR), crucially activates the adenylate cyclase pathway by coupling with G(s) subunit alpha. Isoform 1, displaying constitutive activity, elevates basal cyclic AMP (cAMP) levels and responds to mechanical stimulation, emphasizing GPR114's functional significance in intracellular signaling cascades and its role in cellular responses to mechanical cues. GPR114 Protein, Human (HEK293, Fc) is the recombinant human-derived GPR114 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of GPR114 Protein, Human (HEK293, Fc) is 163 a.a., with molecular weight of 57-75 kDa.
  • HY-P76961
    GPR133 Protein, Human (HEK293, His)

    Adhesion G-protein coupled receptor D1; G-protein coupled receptor 133; ADGRD1; PGR25

    		 Human HEK293
    GPR133 Protein, an orphan receptor, signals through the G(s)-alpha family of G-proteins, as indicated by studies. Its protumorigenic function, particularly in glioblastoma, suggests a potential role in tumorigenesis-associated pathological processes. GPR133 Protein, Human (HEK293, His) is the recombinant human-derived GPR133 protein, expressed by HEK293 , with C-His labeled tag. The total length of GPR133 Protein, Human (HEK293, His) is 545 a.a., with molecular weight of 90-110 KDa.

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