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  • HY-P72815
    ADAM17/TACE Protein, Rat (HEK293, His)

    Disintegrin and metalloproteinase domain-containing protein 17; ADAM 17; TNF-alpha convertase; CD156b; Tace

    		 Rat HEK293
    ADAM17/TACE Protein, a pivotal enzyme, cleaves TNF-alpha and activates various cell-surface proteins like p75 TNF-receptor. It also mediates the cleavage of Notch, activates the Notch pathway, and contributes to hemostasis by shedding GP1BA. ADAM17/TACE further facilitates the cleavage of LAG3, IL6R, and FCGR3A, showcasing its significance in diverse cellular functions. ADAM17/TACE Protein, Rat (HEK293, His) is the recombinant rat-derived ADAM17/TACE protein, expressed by HEK293 , with C-10*His labeled tag. The total length of ADAM17/TACE Protein, Rat (HEK293, His) is 546 a.a., with molecular weight of 57 & 20 kDa, respectively.

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