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α-glucosidase/PTP1B-IN-1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-168185
    α-glucosidase/PTP1B-IN-1

    		Glucosidase Phosphatase Amylases Metabolic Disease
    α-glucosidase/PTP1B-IN-1 (compound 8a) is a potent α-glucosidase and PTP1B inhibitor with an IC50 value of 66.3 μM and 47.0 μM, respectively. α-glucosidase/PTP1B-IN-1 exhibits excellent activities against α-amylase with an IC50 of 30.62 μM. α-glucosidase/PTP1B-IN-1 can dock into the active pockets of α-glucosidase and PTP1B. α-glucosidase/PTP1B-IN-1 has potential to reduce the postprandial blood glucose and is used for Type 2 diabetes mellitus .
    α-glucosidase/PTP1B-IN-1

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