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Results for "

β-catenin/CBP

" in MedChemExpress (MCE) Product Catalog:
Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-115539
    Windorphen

    		Wnt β-catenin Histone Acetyltransferase Cancer
    Windorphen is a Wnt/β-catenin signal inhibitor that specifically targets the function of the c-terminal transactivation domain of β-catenin-1 but not β-catenin-2. Windorphen selectively targets p300, disrupting the association of the mammalian β-catenin with p300 but not CBP .
    Windorphen
  • HY-111386
    E-7386

    		Epigenetic Reader Domain Cancer
    E-7386 is an orally active CBP/beta-catenin modulator.
    E-7386
  • HY-112045
    Foscenvivint
    1 Publications Verification

    PRI-724

    		 Wnt Cancer
    PRI-724 is a selective inhibitor of the CBP/β-catenin interaction.
    Foscenvivint
  • HY-10593
    IQ 1

    		Wnt Others
    IQ 1 is a Wnt/β-catenin/CBP signalling sustainer. IQ 1 maintains long-term expansion of Wnt/β-catenin-driven mouse embryonic stem cells (ESCs) and prevents spontaneous differentiation by enhancing β-catenin/CBP-mediated transcription and preventing conversion to β-catenin/p300-mediated transcription. IQ-1 regulates Wnt signalling by interacting with PR72/130. IQ 1 can be used in study of ESCs expansion .
    IQ 1
  • HY-14428
    ICG-001
    45+ Cited Publications

    		 β-catenin Apoptosis Cancer
    ICG-001 is an inhibitor of β-catenin/TCF mediated transcription. ICG-001 works by specifically binding to cyclic AMP response element-binding protein with an IC50 of 3 μM. ICG-001 selectively blocks the β-catenin/CBP interaction without interfering with the β-catenin/p300 interaction.
    ICG-001

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