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GalNAz

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (1) Endogenous Metabolite (1) PROTAC Linkers (1)
By Research Areas:	Cancer (1) Metabolic Disease (1)
Click Chemistry:	PROTAC Synthesis (1) Azide (3)
Oligonucleotides:	Nucleotides and their Analogs (1)

3

Inhibitors & Agonists

1

Biochemical Assay Reagents

3

Click Chemistry

1

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

2-[(Azidoacety)amino]-2-deoxy-D-galactose N-Azidoacetylgalactosamine; GalNAz	Biochemical Assay Reagents	Others
2-[(Azidoacety)amino]-2-deoxy-D-galactose targets O-GlcNAc-modified proteins. By detecting and targeting O-GlcNAc-modified proteins, 2-[(Azidoacety)amino]-2-deoxy-D-galactose can serve as a chemical tag for intracellular sugar chain metabolism .

Ac4GalNAz	PROTAC Linkers	Cancer
Ac4GalNAz is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . Ac4GalNAz is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Bovin beta-1,4-galactosyltransferase 1 (Y289L) Bovin B4GALT1 (Y289L)	Endogenous Metabolite	Others
Bovin beta-1,4-galactosyltransferase 1 (Y289L) (Bovin B4GALT1 (Y289L)) is a mutated form of bovine-derived galactosyltransferase with a mutation at the Y289L genetic site. Bovin beta-1,4-galactosyltransferase 1 can label O-GlcNAcylated proteins with an N-azidoacetylgalactosamine (GalNAz) group. This labeling method allows for the specific, unbiased, and global labeling of O-GlcNAcylated proteins. After labeling, the appended azide group can react with a wide variety of alkyne-modified chemical probes, facilitating multiple downstream analyses .

Cat. No.	Product Name	Type

2-[(Azidoacety)amino]-2-deoxy-D-galactose N-Azidoacetylgalactosamine; GalNAz	Carbohydrates
2-[(Azidoacety)amino]-2-deoxy-D-galactose targets O-GlcNAc-modified proteins. By detecting and targeting O-GlcNAc-modified proteins, 2-[(Azidoacety)amino]-2-deoxy-D-galactose can serve as a chemical tag for intracellular sugar chain metabolism .

Cat. No.	Product Name		Classification

2-[(Azidoacety)amino]-2-deoxy-D-galactose N-Azidoacetylgalactosamine; GalNAz		Azide
2-[(Azidoacety)amino]-2-deoxy-D-galactose targets O-GlcNAc-modified proteins. By detecting and targeting O-GlcNAc-modified proteins, 2-[(Azidoacety)amino]-2-deoxy-D-galactose can serve as a chemical tag for intracellular sugar chain metabolism .

Ac4GalNAz		Azide PROTAC Synthesis
Ac4GalNAz is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . Ac4GalNAz is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

*UDP-GalNAz* disodium** UDP-N-azidoacetylgalactosamine disodium		Azide
UDP-GalNAz disodium (UDP-N-azidoacetylgalactosamine disodium) is the analogue of UDP-GalNAc. UDP-GalNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor . UDP-GalNAz (disodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No.	Product Name		Classification

*UDP-GalNAz* disodium** UDP-N-azidoacetylgalactosamine disodium		Nucleotides and their Analogs
UDP-GalNAz disodium (UDP-N-azidoacetylgalactosamine disodium) is the analogue of UDP-GalNAc. UDP-GalNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor . UDP-GalNAz (disodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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