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10-Hydroxy-4(Z),7(Z),11(E),13(Z),16(Z),19(Z)-docosahexaenoic acid

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-130289
    (±)4-HDHA

    4-Hydroxy docosahexaenoic acid; (±)4-HDoHE

    		 PPAR Metabolic Disease Inflammation/Immunology
    (±)4-HDHA (4-Hydroxy docosahexaenoic acid) is an autoxidation product of Docosahexaenoic acid (HY-B2167) (DHA). (±)4-HDHA is a PPARγ agonist, antidiabetic and anti-inflammatory agent .
    (±)4-HDHA
  • HY-130286
    10-Hydroxy-4(Z),7(Z),11(E),13(Z),16(Z),19(Z)-docosahexaenoic acid

    		Others Metabolic Disease
    10-Hydroxy-4(Z),7(Z),11(E),13(Z),16(Z),19(Z)-docosahexaenoic acid is an ester product.
    10-Hydroxy-4(Z),7(Z),11(E),13(Z),16(Z),19(Z)-docosahexaenoic acid
  • HY-120255A
    17(S)-HDHA

    		PPAR Metabolic Disease
    17(S)-HDHA is a pro-resolving mediator (SPM). 17(S)-HDHA slightly activats PPARγ, PPARα and PPARδ .
    17(S)-HDHA
  • HY-113777
    22-HDHA

    22-Hydroxy docosahexaenoic acid; 22-OH DHA

    		 Others Metabolic Disease
    22-HDHA is an oxidation product of docosahexaenoic acid.1 In vitro, it is formed upon incubation of rat liver microsomes with DHA and NADPH and also by the human cytochrome P450 (CYP) isoform CYP4F3B in BTI-TN-5B1-4 microsomes. Serum levels of 22-HDHA increase following dietary DHA supplementation in humans.
    22-HDHA
  • HY-130239A
    (±)14-HDHA

    (±)14-HDoHE; 14-Hydroxy docosahexaenoic acid; (±)14-HDoHE

    		 Drug Metabolite Neurological Disease
    (±)14-HDHA is the isomer of 14(S)-HDHA (HY-130239). 14(S)-HDHA is an oxygenation product of Docosahexaenoic acid (DHA). 14(S)-HDHA is a marker reflecting activation of a Docosahexaenoic acid carbon 14-lipoxygenation pathway .
    (±)14-HDHA
  • HY-130238
    (±)8-HDHA

    (±)8-HDoHE; 8-Hydroxy docosahexaenoic acid; (±)8-HDoHE

    		 Endogenous Metabolite Metabolic Disease
    (±)8-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. (±)8-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.
    (±)8-HDHA
  • HY-130287
    (±)16-HDHA

    (±)16-HDoHE; 16-Hydroxy docosahexaenoic acid; (±)16-HDoHE

    		 Endogenous Metabolite Metabolic Disease
    (±)16-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. (±)16-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.
    (±)16-HDHA
  • HY-130288
    (±)13-HDHA

    (±)13-HDoHE; 13-Hydroxy docosahexaenoic acid; (±)13-HDoHE

    		 Others Inflammation/Immunology
    (±)13-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. Fresh water hydra is shown to metabolize DHA to 13(R)-HDHA, presumably via the 11R-lipoxygenase activity. (±)13-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.
    (±)13-HDHA
  • HY-120255AS
    17(S)-HDHA-d5

    17(S)-Hydroxy docosahexaenoic acid-d5, 17(S)-HDoHE-d5

    		 Isotope-Labeled Compounds Others
    17(S)-HDHA-d5 is the deuterium labeled 17(S)-HDHA[1].
    17(S)-HDHA-d5

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