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1642300-52-4

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100423
    Eltanexor
    1 Publications Verification

    KPT-8602

    		 CRM1 Cancer
    Eltanexor (KPT-8602) is a second-generation, highly specific and orally active exportin-1 (XPO1) inhibitor with potent anti-leukemic activity. Eltanexor (KPT-8602) inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor (KPT-8602) induces Caspase-dependent apoptosis in a panel of leukemic cell lines .
    Eltanexor

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