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2(E),8(Z),11(Z),14(Z)-Eicosatetraenoic acid

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Angiotensin-converting Enzyme (ACE) (1) Biochemical Assay Reagents (3) Endogenous Metabolite (1) Isotope-Labeled Compounds (1)
By Research Areas:	Cardiovascular Disease (2) Inflammation/Immunology (1) Metabolic Disease (5)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Amino Acid Derivatives Hydroxycarboxylic Acid Receptor (HCAR) Free Fatty Acid Receptor Fatty Acid Synthase (FASN) Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-167560

*2(E),8(Z),11(Z),14(Z)-Eicosatetraenoic* acid**	Biochemical Assay Reagents
2(E),8(Z),11(Z),14(Z)-Eicosatetraenoic acid is a kind of biochemical reagent.

HY-165965

*5-Hydroxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic* acid,methyl ester**	Others	Metabolic Disease
5-Hydroxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid,methyl ester is an ester product.

HY-165948

*14(S),15(S)-Dihydroxy-5(Z),8(Z),10(E),12(E)-eicosatetraenoic* acid**	Others	Metabolic Disease
14(S),15(S)-Dihydroxy-5(Z),8(Z),10(E),12(E)-eicosatetraenoic acid is an ester product.

HY-165944

*14(R),15(S)-Dihydroxy-5(Z),8(Z),10(E),12(E)-eicosatetraenoic* acid**	Others	Metabolic Disease
14(R),15(S)-Dihydroxy-5(Z),8(Z),10(E),12(E)-eicosatetraenoic acid is an ester product.

HY-113453A

11-S-Hydroxyeicosatetraenoic acid 11(S)-Hydroxy-5(Z),8(Z),12(E),14(Z)-Eicosatetraenoic acid	Others	Metabolic Disease
11-S-Hydroxyeicosatetraenoic acid (11(S)-Hydroxy-5(Z),8(Z),12(E),14(Z)-eicosatetraenoic acid) is an ester product.

HY-125122

Mulberrofuran A	Others	Inflammation/Immunology
Mulberrofuran A is a natural product, that can be isolated from the root bark of mulberry tree. Mulberrofuran A inhibits the formations of 12-hydroxy-,8,10-heptadecatrienoic acid (HHT) and thromboxane B2 (cyclooxygenase products), but it increases the formation of 12-hydroxy-5,8,10,14-eicosatetraenoic acid (12-HETE) (12-lipoxygenase product) .

HY-130309

(±)8(9)-EpETE (±)8,9-EEQ; (±)8,9-epoxy Eicosatetraenoic acid	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Eicosapentaenoic acid (EPA) is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±)17(18)-EpETE, relaxes vascular and airway smooth muscle by activating large conductance Ca ²⁺-activated K ⁺ (BKCa) channels by directly interacting with BKα channel subunits. (±)8(9)-EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo.

HY-112653A

(±)8-HETE 8-Hydroxy-5(Z),9(E),11(Z),14(Z)-Eicosatetraenoic acid	Endogenous Metabolite	Metabolic Disease
(±)8-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of Arachidonic acid (HY-109590). The biological activity of (±)8-HETE is likely to resemble that of its constituent enantiomers (8(R)-HETE and 8(S)-HETE).

HY-165024

(±)5(6)-Epete methyl ester (±)5,6-EEQ methyl ester; (±)5,6-Epoxy Eicosatetraenoic acid methyl ester	Others	Others
(±)5(6)-Epete methyl ester is a derivative of 5(6)-Epete .

HY-120978

Omega-3 arachidonic acid methyl ester ω-3 Arachidonic acid methyl ester; (all-Z)-8,11,14,17-Eicosatetraenoic acid methyl ester	Biochemical Assay Reagents	Others
omega-3 Arachidonic Acid methyl ester, mainly docosahexaenoic acid, eicosapentaenoic acid and α-Linoleic acid, represented by linoleic acid, is an essential dietary nutrient required for normal growth and development.Omega-3Methyl arachidonic acid is a rare fatty acid Omega-3Neutral fat-soluble form of arachidonic acid. Omega-3Fatty acids, as a group, were associated with reduced inflammation and autoimmune activity, as well as reduced thrombosis and platelet activation.

HY-125140S

ω-3 Arachidonic Acid-d8 8(Z),11(Z),14(Z),17(Z)-Eicosatetraenoic-8,9,11,12,14,15,17,18-d₈ acid	Isotope-Labeled Compounds	Others
ω-3 Arachidonic Acid-d₈ is the deuterium labeled ω-3 Arachidonic Acid[1].

HY-125139

omega-3 Arachidonic acid ethyl ester, in ethanol, 98% ω-3 Arachidonic acid ethyl ester, in ethanol, 98%; (all-Z)-8,11,14,17-Eicosatetraenoic acid ethyl ester, in ethanol, 98%	Biochemical Assay Reagents	Cardiovascular Disease Others
omega-3 Arachidonic acid ethyl ester, in ethanol, 98% is a rare polyunsaturated fatty acid found in very small amounts in dietary sources. Omega-3 fatty acids are known to be essential for the growth and development of infants, and they protect against heart disease, blood clots, high blood pressure, and inflammatory and autoimmune diseases. In human platelet membranes, omega-3 arachidonic acid inhibits arachidonyl-CoA synthetase with a Ki of 14 μM. It also inhibits arachidonoyl-CoA synthetase in calf brain extract with an IC50 of approximately 5 μM. Omega-3 ethyl arachidonate is the more lipophilic form of the free acid.

Cat. No.	Product Name	Type

HY-125139

omega-3 Arachidonic acid ethyl ester, in ethanol, 98% ω-3 Arachidonic acid ethyl ester, in ethanol, 98%; (all-Z)-8,11,14,17-Eicosatetraenoic acid ethyl ester, in ethanol, 98%	Drug Delivery
omega-3 Arachidonic acid ethyl ester, in ethanol, 98% is a rare polyunsaturated fatty acid found in very small amounts in dietary sources. Omega-3 fatty acids are known to be essential for the growth and development of infants, and they protect against heart disease, blood clots, high blood pressure, and inflammatory and autoimmune diseases. In human platelet membranes, omega-3 arachidonic acid inhibits arachidonyl-CoA synthetase with a Ki of 14 μM. It also inhibits arachidonoyl-CoA synthetase in calf brain extract with an IC50 of approximately 5 μM. Omega-3 ethyl arachidonate is the more lipophilic form of the free acid.

omega-3 Arachidonic acid ethyl ester, in ethanol, 98%

ω-3 Arachidonic acid ethyl ester, in ethanol, 98%; (all-Z)-8,11,14,17-Eicosatetraenoic acid ethyl ester, in ethanol, 98%

Drug Delivery

omega-3 Arachidonic acid ethyl ester, in ethanol, 98% is a rare polyunsaturated fatty acid found in very small amounts in dietary sources. Omega-3 fatty acids are known to be essential for the growth and development of infants, and they protect against heart disease, blood clots, high blood pressure, and inflammatory and autoimmune diseases. In human platelet membranes, omega-3 arachidonic acid inhibits arachidonyl-CoA synthetase with a Ki of 14 μM. It also inhibits arachidonoyl-CoA synthetase in calf brain extract with an IC50 of approximately 5 μM. Omega-3 ethyl arachidonate is the more lipophilic form of the free acid.

HY-167560

*2(E),8(Z),11(Z),14(Z)-Eicosatetraenoic* acid**	Drug Delivery
2(E),8(Z),11(Z),14(Z)-Eicosatetraenoic acid is a kind of biochemical reagent.

HY-120978

Omega-3 arachidonic acid methyl ester ω-3 Arachidonic acid methyl ester; (all-Z)-8,11,14,17-Eicosatetraenoic acid methyl ester	Drug Delivery
omega-3 Arachidonic Acid methyl ester, mainly docosahexaenoic acid, eicosapentaenoic acid and α-Linoleic acid, represented by linoleic acid, is an essential dietary nutrient required for normal growth and development.Omega-3Methyl arachidonic acid is a rare fatty acid Omega-3Neutral fat-soluble form of arachidonic acid. Omega-3Fatty acids, as a group, were associated with reduced inflammation and autoimmune activity, as well as reduced thrombosis and platelet activation.

Omega-3 arachidonic acid methyl ester

ω-3 Arachidonic acid methyl ester; (all-Z)-8,11,14,17-Eicosatetraenoic acid methyl ester

Drug Delivery

omega-3 Arachidonic Acid methyl ester, mainly docosahexaenoic acid, eicosapentaenoic acid and α-Linoleic acid, represented by linoleic acid, is an essential dietary nutrient required for normal growth and development.Omega-3Methyl arachidonic acid is a rare fatty acid Omega-3Neutral fat-soluble form of arachidonic acid. Omega-3Fatty acids, as a group, were associated with reduced inflammation and autoimmune activity, as well as reduced thrombosis and platelet activation.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-125139

omega-3 Arachidonic acid ethyl ester, in ethanol, 98% ω-3 Arachidonic acid ethyl ester, in ethanol, 98%; (all-Z)-8,11,14,17-Eicosatetraenoic acid ethyl ester, in ethanol, 98%	Cardiovascular Disease Classification of Application Fields Disease Research Fields	Biochemical Assay Reagents
omega-3 Arachidonic acid ethyl ester, in ethanol, 98% is a rare polyunsaturated fatty acid found in very small amounts in dietary sources. Omega-3 fatty acids are known to be essential for the growth and development of infants, and they protect against heart disease, blood clots, high blood pressure, and inflammatory and autoimmune diseases. In human platelet membranes, omega-3 arachidonic acid inhibits arachidonyl-CoA synthetase with a Ki of 14 μM. It also inhibits arachidonoyl-CoA synthetase in calf brain extract with an IC50 of approximately 5 μM. Omega-3 ethyl arachidonate is the more lipophilic form of the free acid.

HY-125122

Mulberrofuran A	Structural Classification Monophenols Source classification Phenols Morus alba L. Plants Moraceae	Others
Mulberrofuran A is a natural product, that can be isolated from the root bark of mulberry tree. Mulberrofuran A inhibits the formations of 12-hydroxy-,8,10-heptadecatrienoic acid (HHT) and thromboxane B2 (cyclooxygenase products), but it increases the formation of 12-hydroxy-5,8,10,14-eicosatetraenoic acid (12-HETE) (12-lipoxygenase product) .

HY-112653A

(±)8-HETE 8-Hydroxy-5(Z),9(E),11(Z),14(Z)-Eicosatetraenoic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
(±)8-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of Arachidonic acid (HY-109590). The biological activity of (±)8-HETE is likely to resemble that of its constituent enantiomers (8(R)-HETE and 8(S)-HETE).

Cat. No.	Product Name	Chemical Structure

HY-125140S

ω-3 Arachidonic Acid-d8
ω-3 Arachidonic Acid-d₈ is the deuterium labeled ω-3 Arachidonic Acid[1].

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2(E),8(Z),11(Z),14(Z)-Eicosatetraenoic acid

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Natural
Products