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2052301-24-1

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-120084
    BTX161

    		Casein Kinase Cancer
    BTX161, a Thalidomide analog, is a potent CKIα degrader, and belonging to PROTAC related Ligands for E3 Ligase. BTX161 mediates degradation of CKIα better than Lenalidomide in human AML cells and activates DNA damage response (DDR) and p53, while stabilizing the p53 antagonist MDM2 .
    BTX161

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