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69280-94-0

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-129262
    Deoxypheganomycin D

    		Others Infection
    Deoxypheganomycin D is a specific antimycobacterial inhibitor with activity against the growth of Mycobacterium smegmatis ATCC 607. Deoxypheganomycin D inhibits bacterial growth in a bacteriostatic manner at concentrations up to 7 X 10(-5) M and has no cross-resistance to other antibiotics such as paromomycin, capreomycin, viomycin, streptothricin, kanamycin and streptomycin. Deoxypheganomycin D only partially inhibits the cell growth of M. 607 at 2.8 X 10(-7) M, but has no significant inhibitory effect on DNA, RNA or protein synthesis, while there is a significant reduction in the accumulation of [14C]glycerol-derived radioactive material in the cell wall. Deoxypheganomycin D affects the influx of the amino acid leucine in the presence of 7 X 10(-6) M, while having no effect on the influx of thymidine, whereas the reverse is true for the outflux. The effects of deoxypheganomycin D may be related to cell membrane and specific mycobacterial lipid components .
    Deoxypheganomycin D

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