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Results for "

AP 24534

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12047
    Ponatinib
    25+ Cited Publications

    AP24534

    		 Bcr-Abl PDGFR VEGFR FGFR Src Autophagy Cancer
    Ponatinib (AP24534) is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively .
    Ponatinib
  • HY-108766
    Ponatinib hydrochloride
    25+ Cited Publications

    AP24534 hydrochloride

    		 Bcr-Abl FGFR PDGFR VEGFR Src Autophagy Infection Cancer
    Ponatinib hydrochloride (AP24534 hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively .
    Ponatinib hydrochloride
  • HY-12047S
    Ponatinib-d8

    AP24534-d8

    		 Bcr-Abl PDGFR VEGFR FGFR Src Autophagy Cancer
    Ponatinib-d8 is a deuterium labeled Ponatinib. Ponatinib (AP24534) is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively.
    Ponatinib-d8
  • HY-12047R
    Ponatinib (Standard)

    		Bcr-Abl PDGFR VEGFR FGFR Src Autophagy Cancer
    Ponatinib (Standard) is the analytical standard of Ponatinib. This product is intended for research and analytical applications. Ponatinib (AP24534) is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively .
    Ponatinib (Standard)

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