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Results for "

Ebola pseudotype virus

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W395779
    EBOV-IN-1

    		Filovirus Infection
    EBOV-IN-1 (com 3.47) is an adamantane dipeptide piperazine and an inhibitor of Ebola virus (EBOV). EBOV-IN-1 targets Niemann-Pick C1 (NPC1) and inhibits its binding to the EBOV glycoprotein (GP) that activates and mediates viral penetration into host cells, thereby inhibiting EBOV infection. EBOV-IN-1 inhibits pseudotyped EBOV infection with an IC50 of 13 nM .
    EBOV-IN-1
  • HY-160877
    EBOV-IN-2

    		Filovirus Infection
    EBOV-IN-2 (Compound 2) is an inhibitor of Ebola virus (EBOV) with IC50 values of 0.37 μM and 2.54 μM against Ebola virus glycoprotein pseudotype virus (pEBOV) and African swine fever virus (ASFV), respectively .
    EBOV-IN-2
  • HY-160883
    EBOV-IN-8

    		Filovirus Infection
    EBOV-IN-8 (Compound 30) inhibits Ebola pseudotyped virus (pEBOV) infection with an IC50 of 62.1% at 10 μM .
    EBOV-IN-8
  • HY-139223
    pEBOV-IN-1

    		Filovirus Infection Inflammation/Immunology
    pEBOV-IN-1 (Comp 2) is a pEBOV inhibitor, with an EC50 value of 0.38 μM. pEBOV: pseudotyped Ebola virus .
    pEBOV-IN-1
  • HY-160879
    EBOV-IN-4

    		Filovirus Infection
    EBOV-IN-4 (compound 12), a benzothiazepine, is a potent Ebola virus (EBOV) inhibitor with 64.9% inhibitory for EBOV-GP-pseudotype virus (pEBOV) with 10 μM. EBOV-IN-4 is inactive with ASFV .
    EBOV-IN-4
  • HY-160882
    EBOV-IN-7

    		Filovirus Infection
    EBOV-IN-7 (compound 26) is an inhibitor of the Ebola virus EBOV with an IC50 of 2.04 μM against EBOV-GP pseudotyped virus (pEBOV). EBOV-IN-7 has inhibitory effects on cancer cells and inhibits the EBOV-GPcl/NPC1 interaction .
    EBOV-IN-7
  • HY-139111
    Oxocarbazate

    		Cathepsin Infection
    Oxocarbazate is an inhibitor of human cathepsin L with the IC50 values of 6.9 nM (human Cathepsin L,0 h) 0.4 nM ((human Cathepsin L,4 h) and 5.07 μM (human cathepsin B), respectively. Oxocarbazate blockes both SARS-CoV (IC50 = 273 nM) and Ebola virus (IC50 = 193 nM) entry into 293T cells .
    Oxocarbazate

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